ChemistrySelect,
Journal Year:
2025,
Volume and Issue:
10(13)
Published: April 1, 2025
Abstract
The
use
of
Schiff
bases
especially
in
chemistry,
medicine,
pharmacy,
and
various
industries
has
increased
the
importance
these
compounds.
their
derivatives
show
important
bioactive
properties
a
wide
range.
Compounds
containing
phenol
its
molecular
structures
have
potential
to
capture
free
radicals
associated
with
diseases.
In
this
study,
five
new
(13–17)
having
piperidine
rings
groups,
which
be
used
as
antioxidants,
were
synthesized
for
first
time
using
microwave
energy.
antioxidant
effects
compounds
syntheses
(7–12)
obtained
inhibitory
abilities
against
some
metabolic
enzymes
including
acetylcholinesterase
(AChE)
human
carbonic
anhydrases
I
II
(hCAs
hCAs
II)
determined.
addition
experimental
findings,
docking
studies
performed
order
provide
ideas
on
structure‐based
drug
design
(PDB
ID:
4EY6).
light
results
obtained,
it
is
thought
that
study
will
useful
guide
food,
medical,
pharmaceutical
future.
ChemistrySelect,
Journal Year:
2025,
Volume and Issue:
10(13)
Published: April 1, 2025
Abstract
The
use
of
Schiff
bases
especially
in
chemistry,
medicine,
pharmacy,
and
various
industries
has
increased
the
importance
these
compounds.
their
derivatives
show
important
bioactive
properties
a
wide
range.
Compounds
containing
phenol
its
molecular
structures
have
potential
to
capture
free
radicals
associated
with
diseases.
In
this
study,
five
new
(13–17)
having
piperidine
rings
groups,
which
be
used
as
antioxidants,
were
synthesized
for
first
time
using
microwave
energy.
antioxidant
effects
compounds
syntheses
(7–12)
obtained
inhibitory
abilities
against
some
metabolic
enzymes
including
acetylcholinesterase
(AChE)
human
carbonic
anhydrases
I
II
(hCAs
hCAs
II)
determined.
addition
experimental
findings,
docking
studies
performed
order
provide
ideas
on
structure‐based
drug
design
(PDB
ID:
4EY6).
light
results
obtained,
it
is
thought
that
study
will
useful
guide
food,
medical,
pharmaceutical
future.
