Raphanus sativus functional potential: Impact of the analytical extraction technique on the bioaccessibility interpretation

Food Safety and Health, Journal Year: 2023, Volume and Issue: 1(1), P. 93 - 101

Published: July 1, 2023

Abstract Radishes ( Raphanus sativus L.) are cruciferous vegetables with remarkable nutraceutical properties given their distinctive isothiocyanates (ITCs) profile. These compounds formed after glucosinolates‐Myrosinase enzymolysis. Although it is important to characterize radishes' ITCs levels, also necessary evaluate the bioactive compounds' physiological fate radishes ingestion. To do so, extraction techniques should adapt such conditions of high aqueous environment. In this work, we studied bioaccessibility and indole‐3‐carbinol (I3C) in taproots considering analytical implications biological process. Results showed that indole profiles radish's aqueous‐myrosinase hydrolysis followed by Dispersive Liquid‐Liquid Microextraction were distinctively different from other reports. After vitro digestion, raphasatin highest despite its low quantitative yields. Notably, I3C S‐Sulforaphene become promising phytochemicals, due considerable remaining amounts digestion.

Language: Английский

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Chia Phenolic Extract Appear to Improve Small Intestinal Functionality, Morphology, Bacterial Populations, and Inflammation Biomarkers In Vivo (Gallus gallus)

Nutrients, Journal Year: 2023, Volume and Issue: 15(16), P. 3643 - 3643

Published: Aug. 19, 2023

Phenolic compounds can act as a substrate for colonic resident microbiota. Once the metabolites are absorbed and distributed throughout body, they have diverse effects on gut. The objective of this study was to evaluate intra-amniotic administration chia phenolic extract intestinal inflammation, barrier, brush border membrane functionality, microbiota, morphology in vivo (

Language: Английский

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Functional properties of chia (Salvia hispanica L.) flour, its hydrolyzed protein and phenolic extract on microbiota and gut health in vivo

Published: Dec. 19, 2023

Chia has a composition with potential to promote changes in the intestinal tissue that favor its functionality, morphology, and microbiota. Objective: evaluate functional properties of chia flour, hydrolyzed protein phenolics on microbiota gut health vivo. Methodology: four experimental trials were conducted. First experiment: 32 male Wistar rats received following diets (5 weeks): standard (SD), SD+chia, high-fat diet (HFD), or HFD+chia. Second 64 female fed either SD HFD (7 weeks). Then, underwent ovariectomy (OVX) while surgery without removal ovary (SHAM). After 3-week recovery period, divided into eight groups (8 SD, HFD, HFD+chia, for both OVX SHAM groups. Intestinal microbiota, short-chain fatty acids (SCFA), IgA production, pH, histomorphometry, brush border membrane functionality analyzed. systematic review was conducted according PRISMA guidelines, answer question: “How does food derived bioactive peptides can impact inflammatory mediators vivo?”. The third fourth experiments ovo. Third 45 fertile eggs (Gallus gallus) five receiving different treatments: not injected; 18MΩH20; 10mg/mL (1%); protein+106 CFU Lacticaseibacillus paracasei 106 paracasei. Fourth 27 three groups: 18MΩH 20; (1%) phenolic extract. Upon hatching, animals euthanized analysis composition, gene expression related inflammation, barrier proteins. Results: Paper 1: flour consumption increased SCFA production improved circular muscle layer. Diversity abundance bacteria affected, but richness increased. Proteins associated downregulated. 2: In rats, intake acetic butyric decreased cecum content layers crypt thickness, diversity, Ap Si. 3: group propionic acid pH cecal content, reducing concentration HFD+chia group. Nevertheless, it microbial diversity. SD+chia Si Sglt1 Pept1. 4: highlighted positive effects inflammation health. 5: downregulated Tnf-α, Ocln, Muc2, Ap, reduced Bifidobacterium, Lactobacillus morphology. 6: extract Tnf-α expression, E. coli populations Paneth cell diameter, depth crypt, maintained villus height. Conclusion: be considered biological improve demonstrated fractions seed. Key words: Microbiota; Morphology; Short Chain Fatty Acids; Functionality; Intra-Amniotic Administration; paracasei; Brush Border Membrane; Ovariectomy.

Language: Английский

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Antioxidant Properties of Orange Peel and Their Implications for Health: A Comprehensive Review

Journal of Food Chemistry and Nanotechnology, Journal Year: 2023, Volume and Issue: 9

Published: Nov. 15, 2023

Despite being historically relegated as a by-product, orange peel (OP) has gained prominence source of beneficial phytochemicals, such flavonoids, phenolic acids, carotenoids, and limonoids.These compounds collectively confer potent free radical scavenging capabilities, offering robust protection against oxidative stress-induced cellular damage.For instance, OP been considered tale cultural significance for its outstanding properties.Besides, contains great variety antioxidants nutrients that contribute to health-promoting benefits.The present study addresses various methodologies employed in the evaluation antioxidant capability, while also addressing factors influencing bioavailability absorption.Additionally, we underscore diverse health implications associated with consumption OP-derived antioxidants, encompassing their potential mitigate stress-related disorders.Moreover, this work presents methods assessing capacity OP.Specifically, review brings together several essential aspects from perspective.This mainly includes OP, cardiovascular dermatological well-being, bolstering immune system, protecting neurological functions, potentially contributing prevention cancer maintenance gastrointestinal health.Finally, practical dietary suggestions integrating due attention safety considerations.In nutshell highlights incorporation derived OPs into contemporary healthcare approaches promote improved overall health.

Language: Английский

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