Grape Pomace as a Source of Phenolics for the Inhibition of Starch Digestion Enzymes: A Comparative Study and Standardization of the Efficacy DOI Creative Commons
P.S.C. Sri Harsha, Vera Lavelli

Foods, Journal Year: 2024, Volume and Issue: 13(24), P. 4103 - 4103

Published: Dec. 18, 2024

The increase in the incidence of hyperglycemia and diabetes poses challenge finding cost-effective natural inhibitors starch digestion enzymes. Among compounds, phenolics have been considered as promising candidates. aims this study were follows: (a) to investigate effectiveness inhibition different winemaking byproducts towards intestinal brush border α-glucosidase pancreatic α-amylase vitro; (b) calculate an efficacy index relative standard acarbose for phenolic pool byproducts, well isolated compounds pools plants studied literature, order rank with respect reference drug other alternatives. red grape skins showed highest inhibitory activities both α-amylase, which were, on average, 4.9 2.6 µg equivalents/µg total (µg Ac eq/µg GAE), respectively. A correlation was observed between contents their effectiveness, is useful standardizing extracts obtained from processes. In general, activity higher than those namely anthocyanins monomeric polymeric flavanols flavonols, probably due synergistic effects among compounds. Hence, bioactive fractions could be produced focus functionality rather purity, line principles sustainable processing. Based developed compare phenolic-rich literature enzyme inhibitors, proved

Language: Английский

Exploring the Biological Value of Red Grape Skin: Its Incorporation and Impact on Yogurt Quality DOI Creative Commons
Eugenia Covaliov, Tatiana Capcanari, Vladislav Reșitca

et al.

Foods, Journal Year: 2024, Volume and Issue: 13(20), P. 3254 - 3254

Published: Oct. 13, 2024

The study was conducted to the sustainability and enhanced nutrition gains obtained from incorporating grape skin powder (GSP) extracted both Fetească Neagră Rară varieties into yogurt. Grape skins are major leftovers wineries, having high amounts of phenolic compounds dietary fiber responsible for their ability improve characteristics food. research aimed evaluate effect GSP addition at varying concentrations (0.5%, 1.0%, 1.5%) on yogurt's physicochemical properties, antioxidant activity, color parameters, sensory attributes. Analysis revealed that increased total content activity; however, showed greater improvements, with TPC reaching 1.52 mg GAE/100 g DPPH inhibition up 26.63%. Although slightly lower, rose 1.43 18.93% enhancing these parameters conversely. Color changes were observed in fortified yogurts where lightness decreased (

Language: Английский

Citations

0
Grape Pomace as a Source of Phenolics for the Inhibition of Starch Digestion Enzymes: A Comparative Study and Standardization of the Efficacy DOI Creative Commons
P.S.C. Sri Harsha, Vera Lavelli

Foods, Journal Year: 2024, Volume and Issue: 13(24), P. 4103 - 4103

Published: Dec. 18, 2024

The increase in the incidence of hyperglycemia and diabetes poses challenge finding cost-effective natural inhibitors starch digestion enzymes. Among compounds, phenolics have been considered as promising candidates. aims this study were follows: (a) to investigate effectiveness inhibition different winemaking byproducts towards intestinal brush border α-glucosidase pancreatic α-amylase vitro; (b) calculate an efficacy index relative standard acarbose for phenolic pool byproducts, well isolated compounds pools plants studied literature, order rank with respect reference drug other alternatives. red grape skins showed highest inhibitory activities both α-amylase, which were, on average, 4.9 2.6 µg equivalents/µg total (µg Ac eq/µg GAE), respectively. A correlation was observed between contents their effectiveness, is useful standardizing extracts obtained from processes. In general, activity higher than those namely anthocyanins monomeric polymeric flavanols flavonols, probably due synergistic effects among compounds. Hence, bioactive fractions could be produced focus functionality rather purity, line principles sustainable processing. Based developed compare phenolic-rich literature enzyme inhibitors, proved

Language: Английский

Citations

0