Current advances in the biosynthesis and sustainable production strategies of carotenoids and their multifaceted applications in the food industry: A comprehensive review

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 105864 - 105864

Published: Jan. 1, 2025

Language: Английский

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Bee Pollen Phytochemicals and Nutrients as Unequaled Pool of Epigenetic Regulators: Implications for Age-Related Diseases

Foods, Journal Year: 2025, Volume and Issue: 14(3), P. 347 - 347

Published: Jan. 21, 2025

Bee pollen is characterized by an exceptional diversity and abundance of micronutrients bioactive phytochemicals. This richness remains very sparsely investigated, but accumulating evidence strongly supports a promising future for bee in human nutrition medicine. Epigenetic regulation among the most compelling biomedical topics that remain completely untapped derivative research. In our current research, we identified numerous ubiquitous compounds are consistently present this matrix, regardless its botanical geographical origins, have been well studied documented as epigenetic regulators recent years. Given relative newness both research studies within nutritional, pharmaceutical, medical sciences, review aims to bridge these valuable fields advance related experimental investigations. To best knowledge, first work has aimed comprehensively investigate modulatory potential compounds. Our findings also unveiled several intriguing phenomena, such dual effect same compound depending on cellular context or some cross-generational heritability traits. Although whole extract still lacking, study clearly indicates avenue worth further We hope constitutes foundational cornerstone investigations

Language: Английский

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Broccoli: A Multi-Faceted Vegetable for Health: An In-Depth Review of Its Nutritional Attributes, Antimicrobial Abilities, and Anti-inflammatory Properties

Antibiotics, Journal Year: 2023, Volume and Issue: 12(7), P. 1157 - 1157

Published: July 7, 2023

Broccoli, Brassica oleracea var. italica, has recently gained considerable attention due to its remarkable nutritional composition and numerous health benefits. In this review, the aspects of broccoli are examined, highlighting rich nutrient content essential bioactive compounds. The cruciferous vegetable is a source several important nutrients, including fiber, vitamins (A, C, K), minerals (calcium, potassium, iron), antioxidants. It also been shown contain compounds such as glucosinolates, sulforaphane, indole-3-carbinol, all which have significant health-promoting effects. These chemicals known potent antioxidant, anti-inflammatory, anticancer This review article aims comprehensively examine diverse spectrum nutrients contained in explore medicinal potential promote human health.

Language: Английский

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Carotenoids: Dietary sources, health functions, biofortification, marketing trend and affecting factors – A review

Journal of Agriculture and Food Research, Journal Year: 2023, Volume and Issue: 14, P. 100834 - 100834

Published: Oct. 27, 2023

Nutritional deficiency is becoming a universal problem, resulting in poor health, low worker productivity, high rates of mortality and morbidity. Large-scale dietary improvements are needed to deliver healthy, sustainable diet the increasing world population. Fruits vegetables as well their valorized wastes industrial by-products constitute major sources bioactive compounds, including carotenoids. Carotenoids lipophilic pigments that occur widely nature distributed plants, fish, birds, algae, archaea, yeasts, fungi, bacteria, invertebrate animals (such insects, mites, aphids). The most significant aspects carotenoids human antioxidant provitamin A activities, also color they impart our food. researched diets commonly occurring blood β-carotene, β-cryptoxanthin, lycopene, lutein α-carotene, with β-carotene comprising portion pro-vitamin A. Phytoene phytofluene recently increasingly topical diet. Genotype, environment, climate, post-harvest handling processing among factors affecting Thus, this review, results from several studies on recent developments carotenoid sources, marketability, biofortification, new insights for valorization food agro-industrial by-products, health effects concentrations compositions critically pinpointed briefly discussed. Lastly, research needs, mainly crop waste valorization, therapeutic properties highlighted so enhance production nutritional values potentially benefits.

Language: Английский

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Nutritional Benefits of Lycopene and Beta‐Carotene: A Comprehensive Overview

Food Science & Nutrition, Journal Year: 2024, Volume and Issue: 12(11), P. 8715 - 8741

Published: Oct. 16, 2024

Certain carotene components, such as lycopene and beta-carotene, are found in tomatoes, carrots, sweet potatoes, etc. good for human health. It gives plants their distinctive red color. A class of lipid-soluble natural pigments known carotenoids is the precursor vitamin vital antioxidant defense against peroxides cells tissues. This review provides an overview current state knowledge research on sources, structures, physiochemical properties, absorption metabolism, functional advantages, prevention many diseases associated with beta-carotene. These antioxidants have been linked to a lower risk cardiovascular disease cancer, they also help draw pollinators flowers. Carrots potatoes rich sources which strengthens immune system improves eye The vivid color reproductive organs, including flowers fruits, caused by carotenoid, secondary metabolite that produced plastids. other health advantages attributed lycopene. When ingested through food or supplements, beta-carotene manage prevent number diseases, metabolic, inflammatory, cardiovascular, hepatic, ophthalmic, skeletal, infertility disorders. main point toxicity uncommon, these generally accepted be safe at different doses. Including nutrients your diet can improve general provide illness prevention.

Language: Английский

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Bioactivity and Bioavailability of Carotenoids Applied in Human Health: Technological Advances and Innovation

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(14), P. 7603 - 7603

Published: July 11, 2024

This article presents a groundbreaking perspective on carotenoids, focusing their innovative applications and transformative potential in human health medicine. Research jointly delves deeper into the bioactivity bioavailability of revealing therapeutic uses technological advances that have to revolutionize medical treatments. We explore pioneering which carotenoids are used treat chronic diseases such as cancer, cardiovascular disease, age-related macular degeneration, offering novel protective mechanisms benefits. Our study also shows cutting-edge innovations carotenoid extraction bioavailability, including development supramolecular carriers advanced nanotechnology, dramatically improve absorption efficacy these compounds. These not only ensure consistent quality but tailor therapies each patient's needs, paving way for personalized By integrating latest scientific discoveries techniques, this research provides prospective clinical establishing new benchmark future studies field. findings underscore importance optimizing extraction, administration, bioactivity, methods develop more effective, targeted, treatments, thus visionary insight modern practices.

Language: Английский

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High-Altitude Medicinal Plants as Promising Source of Phytochemical Antioxidants to Combat Lifestyle-Associated Oxidative Stress-Induced Disorders

Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(8), P. 975 - 975

Published: July 23, 2024

Oxidative stress, driven by reactive oxygen, nitrogen, and sulphur species (ROS, RNS, RSS), poses a significant threat to cellular integrity human health. Generated during mitochondrial respiration, inflammation, UV exposure pollution, these damage cells contribute pathologies like cardiovascular issues, neurodegeneration, cancer, metabolic syndromes. Lifestyle factors exert substantial influence on oxidative stress levels, with mitochondria emerging as pivotal players in ROS generation equilibrium. Phytochemicals, abundant plants, such carotenoids, ascorbic acid, tocopherols polyphenols, offer diverse antioxidant mechanisms. They scavenge free radicals, chelate metal ions, modulate signalling pathways mitigate damage. Furthermore, plants thriving high-altitude regions are adapted extreme conditions, synthesize secondary metabolites, flavonoids phenolic compounds bulk quantities, which act form robust defence against including radiation temperature fluctuations. These promising sources for drug development, offering innovative strategies manage stress-related ailments enhance Understanding harnessing the potential of phytochemicals from represent crucial steps combating stress-induced disorders promoting overall wellbeing. This study offers comprehensive summary production physio-pathological aspects lifestyle-induced explores antioxidants. Additionally, it presents an appraisal medicinal antioxidants, highlighting their development creation therapeutic approaches.

Language: Английский

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Element and carotenoid contents in the oyster Crassostrea gigas (Thunberg, 1793) with different shell pigmentation intensities

Aquaculture International, Journal Year: 2025, Volume and Issue: 33(2)

Published: Jan. 2, 2025

Language: Английский

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Impact of Ketogenic and Mediterranean Diets on Gut Microbiota Profile and Clinical Outcomes in Drug-Naïve Patients with Diabesity: A 12-Month Pilot Study

Metabolites, Journal Year: 2025, Volume and Issue: 15(1), P. 22 - 22

Published: Jan. 6, 2025

Background/Objectives: Managing type 2 diabetes mellitus (T2DM) and obesity requires a multidimensional, patient-centered approach including nutritional interventions (NIs) physical activity. Changes in the gut microbiota (GM) have been linked to metabolic alterations typical of T2DM obesity, they are strongly influenced by diet. However, few studies evaluated effects on GM very-low-calorie ketogenic diet (VLCKD) patients with T2DM, especially mid-term long-term. This longitudinal study is aimed at evaluating long-term impact VLCKD Mediterranean (MD) anthropometric, metabolic, lifestyle parameters 11 (diabesity). extends previously published results short-term (three months) these NIs same patients. Methods: At baseline, were randomly assigned either (KETO group) or (MEDI group). After two months, KETO group gradually shifted (VLCKD-MD), according current guidelines. From fourth month until end both groups followed similar MD. Previous showed that had more beneficial than MD several variables for 3 months NI. In this study, analyses extended six (T6) twelve (T12) NI comparing data prospectively against baseline (T0). The analysis was performed through next-generation sequencing. Results: Improvements anthropometric pronounced T6, particularly body mass index (−5.8 vs. −1.7 kg/m2; p = 0.006) waist circumference (−15.9 −5.2 cm; 0.011). significant improvement HbA1c (6.7% 5.5% 0.02) triglyceride (158 95 mg/dL 0.04) values compared T0 observed only group, which maintained achieved T3. VLCKD-MD phenotype. A substantial positive modulatory effect up sixth due progressive increase bacterial markers human health. month, most health decreased, though still increased baseline. Among them, Verrucomicrobiota phylum identified as main biomarker together its members Verrucomicrobiae, Akkermansiaceae, Verrucomicrobiales, Akkermansia T6 Conclusions: Both dietary approaches ameliorated status, but VLCKD, support MD, has shown greater improvements parameters, well profile,

Language: Английский

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Harnessing the power of nutritional antioxidants against adrenal hormone imbalance-associated oxidative stress

Frontiers in Endocrinology, Journal Year: 2023, Volume and Issue: 14

Published: Nov. 30, 2023

Oxidative stress, resulting from dysregulation in the secretion of adrenal hormones, represents a major concern human health. The present review comprehensively examines various categories endocrine within glands, encompassing glucocorticoids, mineralocorticoids, and androgens. Additionally, comprehensive account hormone disorders, including insufficiency, Cushing’s syndrome, tumors, is presented, with particular emphasis on their intricate association oxidative stress. also delves into an examination nutritional antioxidants, namely vitamin C, E, carotenoids, selenium, zinc, polyphenols, coenzyme Q10, probiotics, elucidates role mitigating adverse effects stress arising imbalances levels. In conclusion, harnessing power antioxidants has potential to help caused by imbalance hormones. This could lead new research therapeutic interventions.

Language: Английский

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