Antimicrobial Potential of the Microalgae Extracts DOI Open Access
А. П. Лыков,

Alexei Salmin,

Р. Г. Геворгиз

et al.

Published: July 24, 2023

Microalgae are a source of carotenoids, phycocyanin, phenol, amino acids, polyunsaturated fatty sulfated polysaccharides, pigments, and other bioactive molecules with antimicrobial, antioxidant, antiviral, antitumor, anti-inflammatory, fat-burning properties. The increasing incidence infectious processes, including tuberculosis, caused by antimicrobial resistant strains microorganisms necessitates the search for alternative sources compounds activity, microalgae. In this study, properties marine freshwater microalgae extracts were evaluated against Gram-positive (Staphylococcus aureus, Enterococcus faecalis, Streptococcus pyogenes) Gram-negative (Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa), Mycobacterium tuberculosis strain H37Rv smegmatis. Water, dimethyl sulfoxide, ethanol used as extractants. obtained extract exhibited cytotoxicity splenocytes and, to lesser extent, peritoneal macrophages CBA mice. bacteriostatic effect bacteria mycobacteria was demonstrated MTT test. addition, activation bacterial mycobacterial growth observed in number cases high levels medium. an expression model mice, decrease load lungs spleen observed. Thus, have moderate weak activity.

Language: Английский

Effects of Microalgae as Biostimulants on Plant Growth, Content of Antioxidant Molecules and Total Antioxidant Capacity in Chenopodium quinoa Exposed to Salt Stress DOI Creative Commons

Sofia Fiorentino,

Lorenza Bellani, Marco Santin

et al.

Plants, Journal Year: 2025, Volume and Issue: 14(5), P. 781 - 781

Published: March 4, 2025

Chenopodium quinoa Willd. is a halophytic plant valued for its nutritional and nutraceutical properties, as well adaptability to diverse soil climatic conditions. Biostimulant application enhances quality resilience under adverse environmental The effects of microalgae extracts (Ettlia pseudoalveolaris Chlorella vulgaris) salt stress (NaCl 100, 200, 300 mM) were evaluated on 7-day-old seedlings two varieties, ‘Tunkahuan’ ‘Regalona’. analysis focused the content antioxidant molecules (total phenolics flavonoids), total capacity (measured by DPPH, 2,2-Diphenyl-1-picrylhydrazyl, FRAP, Ferric Reducing Antioxidant Power, assays), reactive oxygen species (ROS), levels lutein, β-carotene, chlorophyll b. Microalgae treatments significantly increased in both varieties. highest activity, measured DPPH assay, was observed ‘Regalona’, while dose-dependent increase capacity, FRAP evident treated with Ettlia. ROS level reduced Ettlia but not Pigment higher concentrations decreased addition biostimulants. These findings suggest that bioactive compounds, improving salinity resistance increasing value sprouts.

Language: Английский

Citations

0
A Spotlight on the Potential of Microscopic Motile Algae as Novel Sources for Modern Cosmetic Products DOI Creative Commons
Maya Stoyneva‐Gärtner, Blagoy Uzunov, Georg Gärtner

et al.

Cosmetics, Journal Year: 2024, Volume and Issue: 11(4), P. 115 - 115

Published: July 9, 2024

The recognition and use of algae in the very trend-driven cosmetic industry is progressively increasing. Up to now, main focus was on large seaweeds a limited number microalgae. However, motile microalgae, flagellates, remain underscored this aspect, although some them are utilized commercially. Flagellates from different taxonomic groups occupy various habitats contain bioactive high-value multifunctional compounds, which novel. Moreover, they may simultaneously produce substances, together with development downstream processing technologies, makes promising source for modern biotechnology. present review covers data 411 strains, 251 species 110 genera 6 phyla, oriented generally towards less explored flagellates. It demonstrates their great potential as bearers interesting novel compounds that can be beneficially applied cosmetics. Safety aspects both sources products also discussed. Considering gaps knowledge, necessity expand research well-known yet unexplored microalgae shown, encouraging upstreaming processes, including phycoprospecting. Last but not least, paper outlines role living culture collections using good expertise before running biochemical tests, cultivation, bioengineering experiments.

Language: Английский

Citations

2
Processed microalgae: green gold for tissue regeneration and repair DOI Creative Commons
Sheng Liu,

Ling Shi,

Hailong Luo

et al.

Theranostics, Journal Year: 2024, Volume and Issue: 14(13), P. 5235 - 5261

Published: Jan. 1, 2024

As novel biomedical materials, microalgae have garnered significant interest because of their ability to generate photosynthetic oxygen, antioxidant activity, and favorable biocompatibility. Many studies concentrated on the hypoxia-alleviating effects within tumor microenvironments. However, recent findings indicate that can significantly increase regeneration various tissues organs. To augment microalgae's therapeutic efficacy mitigate limitations imposed by immune clearance, it is essential process through processing strategies. This review examines common microalgal species in applications, such as

Language: Английский

Citations

2
Study of the Antimicrobial Potential of the Arthrospira platensis, Planktothrix agardhii, Leptolyngbya cf. ectocarpi, Roholtiella mixta nov., Tetraselmis viridis, and Nanofrustulum shiloi against Gram-Positive, Gram-Negative Bacteria, and Mycobacteria DOI Creative Commons
А. П. Лыков,

Alexei Salmin,

Р. Г. Геворгиз

et al.

Marine Drugs, Journal Year: 2023, Volume and Issue: 21(9), P. 492 - 492

Published: Sept. 14, 2023

The incidence of diseases brought on by resistant strains micro-organisms, including tuberculosis, is rising globally as a result the rapid rise in pathogenic micro-organism resistance to antimicrobial treatments. Secondary metabolites with potential for antibacterial activity are produced cyanobacteria and microalgae. In this study, gram-positive (S. aureus, E. faecalis) gram-negative (K. pneumoniae, A. baumannii, P. aeruginosa) bacteria were isolated from pulmonary tuberculosis patients receiving long-term antituberculosis therapy. extracts Leptolyngbya cf. ectocarpi, Planktothrix agardhii, Arthrospira platensis, Rohotiella mixta sp. nov., Nanofrustulum shiloi, Tetraselmis (Platymonas) viridis Rouchijajnen was evaluated. On mouse splenocytes peritoneal macrophages, microalgae had inhibitory effects. vitro studies have shown that suppress growth mycobacteria. At same time, it has been demonstrated cyanobacterial microalgal can encourage bacterial test tube. Additionally, enhanced fucoxanthin fraction significantly reduced development vitro. experiment simulate mycobacterial load internal organs considerably decreased fucoxanthin. According information gathered, sources compounds be used manufacturing pharmaceutical raw materials.

Language: Английский

Citations

5
Chlamydomonas agloeformis from the Ecuadorian Highlands: Nutrients and Bioactive Compounds Profiling and In Vitro Antioxidant Activity DOI Creative Commons
Teresa Grande, Andrea Vornoli, Valter Lubrano

et al.

Foods, Journal Year: 2023, Volume and Issue: 12(17), P. 3147 - 3147

Published: Aug. 22, 2023

Green microalgae are single-celled eukaryotic organisms that, in recent years, becoming increasingly important the nutraceutical, cosmetic, and pharmaceutical fields because of their high content bioactive compounds. In this study, a particular green microalga was isolated from freshwater highland lakes Ecuador morphologically molecularly identified as Chlamydomonas agloeformis (ChA), it studied for nutritional nutraceutical properties. The phenolic composition fatty acids profile lyophilized cells were determined. methanolic extract analyzed compounds antioxidant capacity by means vitro tests. Finally, Human Microvascular Endothelial Cells (HMEC-1) exploited to explore ChA reduce endothelial damage induced oxidized LDL-mediated oxidative stress. showed good ability thanks polyphenolic observed decrease HMEC-1 also probably due present extract. Based on outcomes our assays, demonstrated be promising source possessing exceptional capacities which make prospective functional food.

Language: Английский

Citations

4
Cryptophytes as potential source of natural antimicrobials for food preservation DOI Creative Commons
Maryam Abidizadegan, Elina Peltomaa, Polina Ilina

et al.

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: Sept. 25, 2024

Cryptophytes are a promising source of bioactive compounds that have not been fully explored. This research investigated the antimicrobial activity total phenolic (TPC) and exopolysaccharides (EPS) extracted from several cryptophytes against range harmful foodborne bacteria fungi. To measure minimum inhibitory concentration (MIC) value, broth microdilution method was used. In antibacterial evaluation TPC, MIC ranged between 31.25 500 μg/mL, while for antifungal test, it varied to 125 μg/mL. test EPS, values 1,000 whereas in susceptibility 62.5 The most resistant pathogen TPC Escherichia coli , Campylobacter jejuni susceptible. case Salmonella Typhimurium, Aspergillus versicolor exhibited highest susceptibility. Overall, terms activity, more effective than EPS. Finally, tolerance level (TL) EPS ≤4 all tested samples, indicating their bactericidal/fungicidal mechanism action. conclusion, isolated demonstrated remarkable properties ability eradicate pathogens, could be considered as natural preservatives food industry.

Language: Английский

Citations

0
Antimicrobial Potential of the Microalgae Extracts DOI Open Access
А. П. Лыков,

Alexei Salmin,

Р. Г. Геворгиз

et al.

Published: July 24, 2023

Microalgae are a source of carotenoids, phycocyanin, phenol, amino acids, polyunsaturated fatty sulfated polysaccharides, pigments, and other bioactive molecules with antimicrobial, antioxidant, antiviral, antitumor, anti-inflammatory, fat-burning properties. The increasing incidence infectious processes, including tuberculosis, caused by antimicrobial resistant strains microorganisms necessitates the search for alternative sources compounds activity, microalgae. In this study, properties marine freshwater microalgae extracts were evaluated against Gram-positive (Staphylococcus aureus, Enterococcus faecalis, Streptococcus pyogenes) Gram-negative (Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa), Mycobacterium tuberculosis strain H37Rv smegmatis. Water, dimethyl sulfoxide, ethanol used as extractants. obtained extract exhibited cytotoxicity splenocytes and, to lesser extent, peritoneal macrophages CBA mice. bacteriostatic effect bacteria mycobacteria was demonstrated MTT test. addition, activation bacterial mycobacterial growth observed in number cases high levels medium. an expression model mice, decrease load lungs spleen observed. Thus, have moderate weak activity.

Language: Английский

Citations

1