Do Novel Nonexercise and Nondrug Treatments Improve Global Cognition in Parkinson's Disease Patients? A Systematic Review and Bayesian Analysis DOI Open Access
Yingle Tang,

Peikun He,

Yanyi Li

et al.

European Journal of Neuroscience, Journal Year: 2025, Volume and Issue: 61(3)

Published: Jan. 31, 2025

ABSTRACT This Bayesian network meta‐analysis method was used to assess the effect of novel treatments on global cognition in patients with Parkinson's disease (PD). We searched randomized controlled trials from PubMed, Cochrane Library, Web Science and Embase investigate for PD until April 10, 2024. Effect size measures were standardized mean differences 95% confidence intervals. included 13 studies investigating traditional paper‐and‐pencil cognitive training, modified training (MCT), repetitive transcranial magnetic stimulation (rTMS), rTMS plus MCT, Mediterranean diet, speech therapy, direct current (tDCS) tDCS MCT. Comparisons between control group revealed following findings: diet (1.25, 0.74–1.76), MCT (0.82, 0.13–1.52), (0.42, 0.08–0.76) (0.34, 0.03–0.66) exhibited statistically significant improvements PD, while remaining did not reveal differences. To conclude, rTMS, MCTs could effectively improve PD.

Language: Английский

Cellular ROS and Antioxidants: Physiological and Pathological Role DOI Creative Commons
Andrey V. Kozlov, Sabzali Javadov, Natascha Sommer

et al.

Antioxidants, Journal Year: 2024, Volume and Issue: 13(5), P. 602 - 602

Published: May 14, 2024

Reactive oxygen species (ROS) are highly reactive derivatives that include free radicals such as superoxide anion radical (O2•−) and hydroxyl (HO•), well non-radical molecules hydrogen peroxide (H2O2), peroxynitrite (ONOO−), hypochlorous acid (HOCl) [...]

Language: Английский

Citations

50
Do Novel Nonexercise and Nondrug Treatments Improve Global Cognition in Parkinson's Disease Patients? A Systematic Review and Bayesian Analysis DOI Open Access
Yingle Tang,

Peikun He,

Yanyi Li

et al.

European Journal of Neuroscience, Journal Year: 2025, Volume and Issue: 61(3)

Published: Jan. 31, 2025

ABSTRACT This Bayesian network meta‐analysis method was used to assess the effect of novel treatments on global cognition in patients with Parkinson's disease (PD). We searched randomized controlled trials from PubMed, Cochrane Library, Web Science and Embase investigate for PD until April 10, 2024. Effect size measures were standardized mean differences 95% confidence intervals. included 13 studies investigating traditional paper‐and‐pencil cognitive training, modified training (MCT), repetitive transcranial magnetic stimulation (rTMS), rTMS plus MCT, Mediterranean diet, speech therapy, direct current (tDCS) tDCS MCT. Comparisons between control group revealed following findings: diet (1.25, 0.74–1.76), MCT (0.82, 0.13–1.52), (0.42, 0.08–0.76) (0.34, 0.03–0.66) exhibited statistically significant improvements PD, while remaining did not reveal differences. To conclude, rTMS, MCTs could effectively improve PD.

Language: Английский

Citations

1