Extraction and purification, pharmacological action, synthesis and product development of salidroside: a review DOI
Yaxiao Liu, Linwei Dan, Jiamei Tang

et al.

Medicinal Chemistry Research, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 8, 2024

Language: Английский

Salidroside Improves Oocyte Competence of Reproductively Old Mice by Enhancing Mitophagy DOI Creative Commons
Jingkai Gu, Renwu Hua,

Huayan Wu

et al.

Aging Cell, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 9, 2025

ABSTRACT The decline of oocyte quality with advanced maternal age has a detrimental effect on female fertility. However, there is limited knowledge therapeutic options and their mechanisms to improve in reproductively older women. In this study, we demonstrated that supplementation salidroside improves the old mice. Salidroside improved maturation, fertilization, developmental competence oocytes from mice by maintaining normal spindle/chromosome structure mitochondrial function. Oocyte transcriptomic micro‐proteomic analysis revealed restores enhancing mitophagy Our studies provide new theoretical foundation for utilizing females context natural fertility or assisted reproduction.

Language: Английский

Citations

0
Effects of Chlorogenic Acid on In Vitro Maturation and Vitrification Cryopreservation of Sheep Oocytes DOI Creative Commons
Tao Hong, Yukun Zhao, Qiang Zhang

et al.

Veterinary Sciences, Journal Year: 2025, Volume and Issue: 12(1), P. 62 - 62

Published: Jan. 16, 2025

Chlorogenic acid (CGA) has strong antioxidant properties. In order to improve the low maturation rate and poor vitrification freezing effect of sheep oocytes caused by oxidative stress. this study, from 200 2-3-year-old Kazakh were collected, different concentrations CGA added medium solution study effects on rate, cleavage blastocyst reactive oxygen species (ROS) glutathione (GSH) levels, mitochondrial membrane potential, expression levels oxidation apoptosis-related genes in oocytes. The results showed that adding 40 μmol/L oocyte vitro significantly increased oocytes, 50 cryopreservative rates mature activated parthenogenetic activation after freezing. During reduced level ROS (Caspase-3 Bax/Bcl-2), (GSH), anti-apoptosis-related (SOD-2 GPX-3). addition, anti-apoptotic gene (AKT) anti-stress (FOXO) during conclusion, improves quality embryos sheep. These provide a basis for production establishment germplasm resource bank.

Language: Английский

Citations

0
Salidroside: Diverse Synthetic Pathways and Recent Advances in Pharmacological Effects Across Multiple Systems DOI
Min Zhao,

Liuxiang Feng,

Wenhua Li

et al.

Pharmacological Research - Natural Products, Journal Year: 2025, Volume and Issue: unknown, P. 100176 - 100176

Published: Feb. 1, 2025

Language: Английский

Citations

0
Integrated metabolomics and transcriptomics reveal the hormesis-like effects of polyethylene microplastics on Pisum sativum L DOI Creative Commons
Zhuang Xiong, Na Zhang, Han Li

et al.

Environmental Technology & Innovation, Journal Year: 2024, Volume and Issue: 37, P. 103972 - 103972

Published: Dec. 14, 2024

Language: Английский

Citations

2
Extraction and purification, pharmacological action, synthesis and product development of salidroside: a review DOI
Yaxiao Liu, Linwei Dan, Jiamei Tang

et al.

Medicinal Chemistry Research, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 8, 2024

Language: Английский

Citations

1