
BMC Veterinary Research, Journal Year: 2025, Volume and Issue: 21(1)
Published: May 22, 2025
Language: Английский
BMC Veterinary Research, Journal Year: 2025, Volume and Issue: 21(1)
Published: May 22, 2025
Language: Английский
Antioxidants, Journal Year: 2025, Volume and Issue: 14(3), P. 370 - 370
Published: March 20, 2025
Korean mistletoe (Viscum album var. coloratum, KML) offers remarkable therapeutic potential for a variety of diseases. This study aims to evaluate the effects and molecular mechanisms KML ethanol extracts (KMLE), focusing on intestinal barrier function tight junctions (TJs) in an interleukin (IL)-6-induced Caco-2 cell monolayer model dextran sodium sulfate (DSS)-induced ulcerative colitis (UC) mouse model. KMLE is non-cytotoxic cells demonstrated strong antioxidant activity. alleviated significant dysfunction protected junction proteins (TJPs) vitro. Furthermore, clinical symptoms histopathological damage, upregulated TJPs, suppressed inflammatory cytokines vivo. Additionally, six bioactive compounds were identified by liquid chromatography-tandem mass spectrometry (LC-MS/MS). In conclusion, ameliorated vitro These findings underscore as agent UC, providing insights into through anti-inflammatory properties its ability restore TJ integrity.
Language: Английский
Citations
1World s Poultry Science Journal, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 36
Published: Feb. 28, 2025
Language: Английский
Citations
0Poultry Science, Journal Year: 2025, Volume and Issue: unknown, P. 105293 - 105293
Published: May 1, 2025
Language: Английский
Citations
0BMC Veterinary Research, Journal Year: 2025, Volume and Issue: 21(1)
Published: May 22, 2025
Language: Английский
Citations
0