Evaluation of leucomethylene blue as a probe for assessing antioxidant activity reveals a potential application in the assessment of male fertility DOI Creative Commons
R. John Aitken, A. L. Wilkins, N. A. Harrison

et al.

Advances in Redox Research, Journal Year: 2025, Volume and Issue: 14, P. 100121 - 100121

Published: Feb. 14, 2025

Language: Английский

A Comparative Analysis of the Antioxidant Profiles Generated by the RoXstaTM System for Diverse Biological Fluids Highlights the Powerful Protective Role of Human Seminal Plasma DOI Creative Commons
R. John Aitken, A. L. Wilkins, N. A. Harrison

et al.

Antioxidants, Journal Year: 2025, Volume and Issue: 14(1), P. 90 - 90

Published: Jan. 14, 2025

(1) Background: The RoXstaTM system has been developed as a rapid, effective means of profiling different types antioxidant activity. purpose this study was to examine its performance utilizing diverse array biological fluids including semen, blood plasma, serum, urine, saliva, follicular fluid and plant extracts. (2) Methods: used assess the ability suppress free radical formation well scavenge variety toxic oxygen metabolites radicals both hydrogen organic peroxides. (3) Results: Human semen shown have significantly (p < 0.001) more peroxide scavenging power than any other tested (10–14 mM vitamin C equivalent compared with 1–2 for serum or plasma), while urine particularly in preventing 0.001). powerful properties human were reside within seminal plasma (SP) fraction, rather spermatozoa, be resistant snap freezing liquid nitrogen. Moreover, comparative studies demonstrated that SP exhibited higher levels potential species examined (stallion, bull, dog) intense activity reflected relative vulnerability spermatozoa attack. (4) Conclusions: provides valuable information on profile complex fluids, supporting diagnostic role conditions associated oxidative stress. Based results secured study, is identified rich source antioxidants capable peroxides, keeping high susceptibility peroxide-mediated damage.

Language: Английский

Citations

1

Evaluation of leucomethylene blue as a probe for assessing antioxidant activity reveals a potential application in the assessment of male fertility DOI Creative Commons
R. John Aitken, A. L. Wilkins, N. A. Harrison

et al.

Advances in Redox Research, Journal Year: 2025, Volume and Issue: 14, P. 100121 - 100121

Published: Feb. 14, 2025

Language: Английский

Citations

0