Protective Role of Physical Activity and Antioxidant Systems During Spermatogenesis DOI Creative Commons
Cristina Antinozzi, Luigi Di Luigi,

Laura Sireno

et al.

Biomolecules, Journal Year: 2025, Volume and Issue: 15(4), P. 478 - 478

Published: March 25, 2025

Oxidative stress is a significant factor that contributes to male infertility and sperm dysfunction. In this condition, an increase in ROS production exceeds the body's antioxidant defenses, resulting decline spermatozoa quality fertilizing capacity. Furthermore, excessive has been linked promotion of genomic damage, lipid peroxidation, inflammation, altered enzyme activity, ultimately, irreversible alterations, cell death, seminal parameters associated with infertility. It established physical activity (PA), acting on inflammatory improving defense, can alleviate negative effects caused by free radicals, offering numerous health benefits positively influencing quality. The objective review highlight mechanisms production, physiological pathophysiological roles relation reproductive system, recent knowledge impact some protocols PA these systems molecular involved.

Language: Английский

Protective Role of Physical Activity and Antioxidant Systems During Spermatogenesis DOI Creative Commons
Cristina Antinozzi, Luigi Di Luigi,

Laura Sireno

et al.

Biomolecules, Journal Year: 2025, Volume and Issue: 15(4), P. 478 - 478

Published: March 25, 2025

Oxidative stress is a significant factor that contributes to male infertility and sperm dysfunction. In this condition, an increase in ROS production exceeds the body's antioxidant defenses, resulting decline spermatozoa quality fertilizing capacity. Furthermore, excessive has been linked promotion of genomic damage, lipid peroxidation, inflammation, altered enzyme activity, ultimately, irreversible alterations, cell death, seminal parameters associated with infertility. It established physical activity (PA), acting on inflammatory improving defense, can alleviate negative effects caused by free radicals, offering numerous health benefits positively influencing quality. The objective review highlight mechanisms production, physiological pathophysiological roles relation reproductive system, recent knowledge impact some protocols PA these systems molecular involved.

Language: Английский

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