Current Topics in Medicinal Chemistry,
Journal Year:
2024,
Volume and Issue:
24(5), P. 416 - 436
Published: Jan. 26, 2024
P-coumaric
acid
is
an
important
phenolic
compound
that
mainly
found
in
fruits,
vegetables,
grains,
and
fungi
also
abundant
Chinese
herbal
medicines.
In
this
review,
the
pharmacological
research
progress
of
p-coumaric
recent
years
was
reviewed,
with
emphasis
on
its
role
mechanism
oxidative
stress-related
diseases,
such
as
inflammation,
cardiovascular
diabetes,
nervous
system
diseases.
Studies
have
shown
has
a
positive
effect
prevention
treatment
these
diseases
by
inhibiting
stress.
addition,
anti-tumor,
antibacterial,
anti-aging
skin
other
effects.
This
review
will
provide
reference
inspiration
for
further
effects
acid.
Dose-Response,
Journal Year:
2023,
Volume and Issue:
21(1)
Published: Jan. 1, 2023
Colorectal
cancer
is
considered
the
second
most
deadly
in
world.
Studies
have
indicated
that
diet
can
prevent
risk
of
developing
colorectal
cancer.
Recently,
there
has
been
an
increasing
interest
polyphenols
due
to
their
plausible
effect
on
prevention
and
treatment.
p-Coumaric
acid
(p-CouA),
a
phenolic
compound,
cinnamic
derivative
found
several
fruits,
vegetables,
herbs.
A
growing
body
evidence
suggests
p-CouA
may
be
effective
agent
for
preventing
managing
In
this
current
review,
we
briefly
highlight
bioavailability
p-CouA.
We
also
provide
up-to-date
overview
molecular
mechanisms
underlying
its
anticancer
effects,
focusing
anti-inflammatory
antioxidant
potentials,
apoptosis
induction,
cell
cycle
blockade.
Finally,
discuss
impact
clonogenicity
multidrug
resistance
cells.
Frontiers in Microbiology,
Journal Year:
2023,
Volume and Issue:
14
Published: Feb. 14, 2023
Biofuels
and
other
biologically
manufactured
sustainable
goods
are
growing
in
popularity
demand.
Carbohydrate
feedstocks
required
for
industrial
fermentation
processes
have
traditionally
been
supplied
by
plant
biomass,
but
the
large
quantities
to
produce
replacement
commodity
products
may
prevent
long-term
feasibility
of
this
approach
without
alternative
strategies
sugar
feedstocks.
Cyanobacteria
under
consideration
as
potential
candidates
production
carbohydrate
feedstocks,
with
potentially
lower
land
water
requirements
relative
plants.
Several
cyanobacterial
strains
genetically
engineered
export
significant
sugars,
especially
sucrose.
Sucrose
is
not
only
naturally
synthesized
accumulated
cyanobacteria
a
compatible
solute
tolerate
high
salt
environments,
also
an
easily
fermentable
disaccharide
used
many
heterotrophic
bacteria
carbon
source.
In
review,
we
provide
comprehensive
summary
current
knowledge
endogenous
sucrose
synthesis
degradation
pathways.
We
summarize
genetic
modifications
that
found
increase
secretion.
Finally,
consider
state
synthetic
microbial
consortia
rely
on
sugar-secreting
strains,
which
co-cultivated
alongside
microbes
able
directly
convert
sugars
into
higher-value
compounds
(e.g.,
polyhydroxybutyrates,
3-hydroxypropionic
acid,
or
dyes)
single-pot
reaction.
recent
advances
reported
such
cyanobacteria/heterotroph
co-cultivation
perspective
future
developments
likely
realize
their
bioindustrial
potential.
Oxygen,
Journal Year:
2024,
Volume and Issue:
4(1), P. 1 - 19
Published: Jan. 22, 2024
A
member
of
the
Verbenaceae
family,
Aloysia
citrodora,
or
lemon
verbena,
is
a
medicinal
herb
with
antioxidant
compounds.
The
aim
this
study
was
to
develop
green,
optimized
method
for
bioactive
compound
(carotenoids,
ascorbic
acid,
and
polyphenols)
extraction
from
verbena
leaves
through
response
surface
methodology
(RSM).
recovery
shown
be
significantly
affected
by
technique
(both
pulsed
electric
field
ultrasound-assisted
extraction),
along
an
solvent,
based
on
partial
least
squares
analysis.
Consequently,
maximum
polyphenol
yield
required
double-assisted
relatively
low
duration
(60
min)
at
high
temperature
(80
°C),
moderate-polarity
solvent
(50%
v/v
ethanol).
With
method,
total
content
(TPC)
measured
175.03
mg
gallic
acid
equivalents/g,
whereas
chromatographic
analysis
revealed
that
verbascoside
most
prevalent
(132.61
mg/g).
optimum
extract
provided
capacity
measurements
FRAP
(1462.17
μmol
equivalents
(AAE)/g),
DPPH
(1108.91
AAE/g),
H2O2
(1662.93
AAE/g).
Total
carotenoids
were
499.61
μg/g,
8.36
μg/g.
Correlation
analyses
negative
correlation
latter
color
coordinates.
This
highlights
potential
used
in
pharmaceutical
food
industries.
Current Topics in Medicinal Chemistry,
Journal Year:
2024,
Volume and Issue:
24(5), P. 416 - 436
Published: Jan. 26, 2024
P-coumaric
acid
is
an
important
phenolic
compound
that
mainly
found
in
fruits,
vegetables,
grains,
and
fungi
also
abundant
Chinese
herbal
medicines.
In
this
review,
the
pharmacological
research
progress
of
p-coumaric
recent
years
was
reviewed,
with
emphasis
on
its
role
mechanism
oxidative
stress-related
diseases,
such
as
inflammation,
cardiovascular
diabetes,
nervous
system
diseases.
Studies
have
shown
has
a
positive
effect
prevention
treatment
these
diseases
by
inhibiting
stress.
addition,
anti-tumor,
antibacterial,
anti-aging
skin
other
effects.
This
review
will
provide
reference
inspiration
for
further
effects
acid.
