Critical Reviews in Immunology,
Journal Year:
2023,
Volume and Issue:
44(3), P. 13 - 23
Published: Dec. 8, 2023
This
study
aimed
to
construct
a
blood
diagnostic
model
for
pancreatic
cancer
(PC)
using
miRNA
signatures
by
combination
of
machine
learning
and
biological
experimental
verification.
Gene
expression
profiles
patients
with
PC
transcriptome
normalization
data
were
obtained
from
the
Expression
Omnibus
(GEO)
database.
Using
random
forest
algorithm,
lasso
regression
multivariate
cox
analyses,
classifier
differentially
expressed
miRNAs
was
identified
based
on
algorithms
functional
properties.
Next,
ROC
curve
analysis
used
evaluate
predictive
performance
model.
Finally,
we
analyzed
two
specific
in
Capan-1,
PANC-1,
MIA
PaCa-2
cells
qRT-PCR.
Integrated
microarray
revealed
that
33
common
exhibited
significant
differences
between
tumor
normal
groups
(P
value
<
0.05
|logFC|
>
0.3).
Pathway
showed
related
P00059
p53
pathway,
hsa04062
chemokine
signaling
cancer-related
pathways
including
PC.
In
ENCORI
database,
hsa-miR-4486
hsa-miR-6075
algorithm
introduced
as
major
markers
diagnosis.
Further,
receiver
operating
characteristic
achieved
area
under
score
80%,
showing
good
sensitivity
specificity
two-miRNA
signature
Additionally,
genes
expressions
three
all
up-regulated
summary,
these
findings
suggest
miRNAs,
hsa-miR-6075,
could
serve
valuable
prognostic
Diagnostics,
Journal Year:
2023,
Volume and Issue:
13(7), P. 1353 - 1353
Published: April 5, 2023
Cancer
is
a
problematic
global
health
issue
with
an
extremely
high
fatality
rate
throughout
the
world.
The
application
of
various
machine
learning
techniques
that
have
appeared
in
field
cancer
diagnosis
recent
years
has
provided
meaningful
insights
into
efficient
and
precise
treatment
decision-making.
Due
to
rapid
advancements
sequencing
technologies,
detection
based
on
gene
expression
data
improved
over
years.
Different
types
affect
different
parts
body
ways.
affects
mouth,
lip,
upper
throat
known
as
oral
cancer,
which
sixth
most
prevalent
form
worldwide.
India,
Bangladesh,
China,
United
States,
Pakistan
are
top
five
countries
highest
rates
cavity
disease
lip
cancer.
major
causes
excessive
use
tobacco
cigarette
smoking.
Many
people's
lives
can
be
saved
if
(OC)
detected
early.
Early
identification
could
assist
doctors
providing
better
patient
care
effective
treatment.
OC
screening
may
advance
implementation
artificial
intelligence
(AI)
techniques.
AI
provide
assistance
oncology
sector
by
accurately
analyzing
large
dataset
from
several
imaging
modalities.
This
review
deals
during
early
stages
for
proper
OC.
Furthermore,
performance
evaluations
DL
ML
models
been
carried
out
show
model
overcome
difficult
challenges
associated
cancerous
lesions
mouth.
For
this
review,
we
followed
rules
recommended
extension
scoping
reviews
meta-analyses
(PRISMA-ScR).
Examining
reference
lists
chosen
articles
helped
us
gather
more
details
subject.
Additionally,
discussed
AI's
drawbacks
its
potential
research
There
methods
reducing
risk
factors,
such
alcohol,
well
immunization
against
HPV
infection
avoid
or
lessen
burden
disease.
officious
preventing
diseases
include
training
programs
patients
facilitating
via
high-risk
populations
Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: Aug. 16, 2024
As
the
burgeoning
field
of
Artificial
Intelligence
(AI)
continues
to
permeate
fabric
healthcare,
particularly
in
realms
patient
surveillance
and
telemedicine,
a
transformative
era
beckons.
This
manuscript
endeavors
unravel
intricacies
recent
AI
advancements
their
profound
implications
for
reconceptualizing
delivery
medical
care.
Through
introduction
innovative
instruments
such
as
virtual
assistant
chatbots,
wearable
monitoring
devices,
predictive
analytic
models,
personalized
treatment
regimens,
automated
appointment
systems,
is
not
only
amplifying
quality
care
but
also
empowering
patients
fostering
more
interactive
dynamic
between
healthcare
provider.
Yet,
this
progressive
infiltration
into
sphere
grapples
with
plethora
challenges
hitherto
unseen.
The
exigent
issues
data
security
privacy,
specter
algorithmic
bias,
requisite
adaptability
regulatory
frameworks,
matter
acceptance
trust
solutions
demand
immediate
thoughtful
resolution
.The
importance
establishing
stringent
far-reaching
policies,
ensuring
technological
impartiality,
cultivating
confidence
paramount
ensure
that
AI-driven
enhancements
service
provision
remain
both
ethically
sound
efficient.
In
conclusion,
we
advocate
an
expansion
research
efforts
aimed
at
navigating
ethical
complexities
inherent
technology-evolving
landscape,
catalyzing
policy
innovation,
devising
applications
are
clinically
effective
earn
populace.
By
melding
expertise
across
disciplines,
stand
threshold
wherein
AI's
role
unimpeachable
conducive
elevating
global
health
quotient.
Biomedicines,
Journal Year:
2023,
Volume and Issue:
11(6), P. 1612 - 1612
Published: June 1, 2023
Oral
cancer
(OC)
is
one
of
the
most
common
forms
head
and
neck
continues
to
have
lowest
survival
rates
worldwide,
even
with
advancements
in
research
therapy.
The
prognosis
OC
has
not
significantly
improved
recent
years,
presenting
a
persistent
challenge
biomedical
field.
In
field
oncology,
artificial
intelligence
(AI)
seen
rapid
development,
notable
successes
being
reported
times.
This
systematic
review
aimed
critically
appraise
available
evidence
regarding
utilization
AI
diagnosis,
classification,
prediction
oral
using
histopathological
images.
An
electronic
search
several
databases,
including
PubMed,
Scopus,
Embase,
Cochrane
Library,
Web
Science,
Google
Scholar,
Saudi
Digital
was
conducted
for
articles
published
between
January
2000
2023.
Nineteen
that
met
inclusion
criteria
were
then
subjected
critical
analysis
utilizing
QUADAS-2,
certainty
assessed
GRADE
approach.
models
been
widely
applied
diagnosing
cancer,
differentiating
normal
malignant
regions,
predicting
patients,
grading
OC.
used
these
studies
displayed
an
accuracy
range
from
89.47%
100%,
sensitivity
97.76%
99.26%,
specificity
ranging
92%
99.42%.
models’
abilities
diagnose,
classify,
predict
occurrence
outperform
existing
clinical
approaches.
demonstrates
potential
deliver
superior
level
precision
accuracy,
helping
pathologists
improve
their
diagnostic
outcomes
reduce
probability
errors.
Considering
advantages,
regulatory
bodies
policymakers
should
expedite
process
approval
marketing
products
application
scenarios.
Frontiers in Microbiology,
Journal Year:
2024,
Volume and Issue:
15
Published: April 17, 2024
Introduction
Antimicrobial
resistance
(AMR)
is
a
global
health
problem
that
requires
early
and
effective
treatments
to
prevent
the
indiscriminate
use
of
antimicrobial
drugs
outcome
infections.
Mass
Spectrometry
(MS),
more
particularly
MALDI-TOF,
have
been
widely
adopted
by
routine
clinical
microbiology
laboratories
identify
bacterial
species
detect
AMR.
The
analysis
AMR
with
deep
learning
still
recent,
most
models
depend
on
filters
preprocessing
techniques
manually
applied
spectra.
Methods
This
study
propose
neural
network,
MSDeepAMR,
learn
from
raw
mass
spectra
predict
MSDeepAMR
model
was
implemented
for
Escherichia
coli,
Klebsiella
pneumoniae,
Staphylococcus
aureus
under
different
antibiotic
profiles.
Additionally,
transfer
test
performed
benefits
adapting
previously
trained
external
data.
Results
showed
good
classification
performance
resistance.
AUROC
above
0.83
in
cases
studied,
improving
results
previous
investigations
over
10%.
adapted
improved
up
20%
when
compared
only
Discussion
demonstrate
potential
their
MS
allow
extrapolation
de
used
need
do
not
capacity
an
extensive
sample
collection.
Current Oncology,
Journal Year:
2024,
Volume and Issue:
31(9), P. 5255 - 5290
Published: Sept. 6, 2024
Artificial
intelligence
(AI)
is
revolutionizing
head
and
neck
cancer
(HNC)
care
by
providing
innovative
tools
that
enhance
diagnostic
accuracy
personalize
treatment
strategies.
This
review
highlights
the
advancements
in
AI
technologies,
including
deep
learning
natural
language
processing,
their
applications
HNC.
The
integration
of
with
imaging
techniques,
genomics,
electronic
health
records
explored,
emphasizing
its
role
early
detection,
biomarker
discovery,
planning.
Despite
noticeable
progress,
challenges
such
as
data
quality,
algorithmic
bias,
need
for
interdisciplinary
collaboration
remain.
Emerging
innovations
like
explainable
AI,
AI-powered
robotics,
real-time
monitoring
systems
are
poised
to
further
advance
field.
Addressing
these
fostering
among
experts,
clinicians,
researchers
crucial
developing
equitable
effective
applications.
future
HNC
holds
significant
promise,
offering
potential
breakthroughs
diagnostics,
personalized
therapies,
improved
patient
outcomes.
Expert Systems,
Journal Year:
2024,
Volume and Issue:
42(1)
Published: Jan. 9, 2024
Abstract
The
most
prevalent
type
of
cancer
worldwide
is
mouth
cancer.
Around
2.5%
deaths
are
reported
annually
due
to
oral
in
2023.
Early
diagnosis
squamous
cell
carcinoma
(OSCC),
a
cavity
cancer,
essential
for
treating
and
recovering
patients.
A
few
computerized
techniques
exist
but
focused
on
traditional
machine
learning
methods,
such
as
handcrafted
features.
In
this
work,
we
proposed
fully
automated
architecture
based
Self‐Attention
convolutional
neural
network
Residual
Network
information
fusion
optimization.
the
framework,
augmentation
process
performed
training
testing
samples,
then
two
developed
deep
models
trained.
self‐attention
MobileNet‐V2
model
trained
using
an
augmented
dataset.
parallel,
DarkNet‐19
same
dataset,
whereas
hyperparameters
have
been
initialized
whale
optimization
algorithm
(WOA).
Features
extracted
from
deeper
layers
both
fused
canonical
correlation
analysis
(CCA)
approach.
CCA
approach
further
optimized
improved
WOA
version
named
Quantum
that
removes
irrelevant
features
selects
only
important
ones.
final
selected
classified
networks
wide
networks.
experimental
dataset
includes
sets:
100×
400×.
Using
sets,
method
obtained
accuracy
98.7%
96.3%.
Comparison
conducted
with
state‐of‐the‐art
(SOTA)
shows
significant
improvement
precision
rate.
2022 6th International Conference on Intelligent Computing and Control Systems (ICICCS),
Journal Year:
2023,
Volume and Issue:
unknown, P. 1252 - 1257
Published: May 17, 2023
Accuracy
is
among
the
most
important
factors
in
a
disease
diagnosis.
It
essential
to
select
characteristics
that
you
find
pertinent
for
highest
accuracy.
This
study
aims
more
accurately
predict
presence
of
primary
stage
squamous
cell
carcinoma
using
fewer
indicators.
Stages
oral
cancer
were
first
demonstrated
be
predicted
by
25
features.
The
variety
features
are
obtained
from
various
patient
records
indirectly
decreased
this
through
combination
unified
medical
system
hybrid
selection
techniques
identify
useful
identification
cancer.
Hybrid
feature
has
been
used
condense
qualities
into
14
diagnosis
patients
with
then
four
classifiers:
Updatable
Naive
Bayes,
Multilayer
Perceptrons,
K-Nearest
Neighbor,
and
Support
Vector
Machines.
Also,
data
show
that,
after
adding
development
decisions
SMOTE
during
preprocessing
phases,
support
vector
machine's
performance
surpasses
other
machine
learning
techniques.
Pharmaceutics,
Journal Year:
2024,
Volume and Issue:
16(2), P. 260 - 260
Published: Feb. 9, 2024
The
use
of
data-driven
high-throughput
analytical
techniques,
which
has
given
rise
to
computational
oncology,
is
undisputed.
widespread
machine
learning
(ML)
and
mathematical
modeling
(MM)-based
techniques
widely
acknowledged.
These
two
approaches
have
fueled
the
advancement
in
cancer
research
eventually
led
uptake
telemedicine
care.
For
diagnostic,
prognostic,
treatment
purposes
concerning
different
types
research,
vast
databases
varied
information
with
manifold
dimensions
are
required,
indeed,
all
this
can
only
be
managed
by
an
automated
system
developed
utilizing
ML
MM.
In
addition,
MM
being
used
probe
relationship
between
pharmacokinetics
pharmacodynamics
(PK/PD
interactions)
anti-cancer
substances
improve
treatment,
also
refine
quality
existing
models
incorporated
at
steps
development
related
routine
patient
This
review
will
serve
as
a
consolidation
benefits
special
focus
on
area
prognosis
anticancer
therapy,
leading
identification
challenges
(data
quantity,
ethical
consideration,
data
privacy)
yet
fully
addressed
current
studies.