Current Microbiology, Journal Year: 2024, Volume and Issue: 81(8)
Published: July 2, 2024
Language: Английский
Molecules, Journal Year: 2025, Volume and Issue: 30(3), P. 622 - 622
Published: Jan. 31, 2025
Citri grandis Exocarpium (Chinese name Huajuhong, HJH) is a traditional Chinese medicinal herb widely used in medicines and foods China due to its efficacy treating coughs excessive phlegm. This study employed HS-SPME-GC-MS analyze the volatile compounds HJH samples from different regions, with aim of distinguishing Huazhou those other origins exploring their potential relationship ecological factors. A multidimensional strategy was utilized relationships between oils, climatic factors, soil elements, examining how responded From 47 batches across various eight significantly were identified, serving as chemical markers for Huazhou. The findings elucidate impact factors on HJH, highlighting environmental relating authenticity results indicate that shaped by unique environments
Language: Английский
Citations
1
Food Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 143938 - 143938
Published: March 1, 2025
Language: Английский
Citations
1
Separations, Journal Year: 2025, Volume and Issue: 12(1), P. 9 - 9
Published: Jan. 5, 2025
Essential oils (EOs) have unique properties, such as antibacterial, antioxidant, and antiviral activities, which are beneficial in various industries, including cosmetics, food, pharmaceuticals. In this study, the antioxidant antimicrobial activities of Pentacalia vaccinioides EOs obtained from leaves flowers (fresh dried plant material) were evaluated using hydrodistillation (HD), steam distillation (SD), simultaneous distillation–extraction (SDE), solid-phase microextraction (SPME) techniques. Antimicrobial activity (minimum inhibitory concentration, MIC) capacity (half-maximal IC50) determined. The identification quantification compounds present conducted by gas chromatography coupled to mass spectrometry (GC-MS). main secondary metabolites identified most samples different extraction techniques included phenol (~18%), 1S-α-pinene (~15%), β-phellandrene (~13%), β-pinene (~12%), 4-terpineol (~10%), γ-terpinene trans-nerolidol (~8%), limonene β-thujene (~6%). HD, SD, SDE exhibited activity, with IC50 values between 621.7 696.6 µg/mL. Additionally, demonstrated bactericidal against Bacillus subtilis Staphylococcus aureus, MIC 5.0 45 µg/mL, respectively. Escherichia coli Pseudomonas aeruginosa did not show susceptibility EOs. This study constitutes first evaluation EOs, demonstrating their bioactive potential relevance method. findings highlight species a promising source natural for therapeutic preservative applications, depending on type material technique used. Future research should investigate how microclimatic conditions development affect chemical composition elucidate molecular mechanisms behind observed bioactivities better understand cellular actions. Furthermore, applications hydrolates pharmaceutical food along exploration extraction-derived hydrolates, offers avenue maximize utility.
Language: Английский
Citations
0
Molecules, Journal Year: 2025, Volume and Issue: 30(3), P. 511 - 511
Published: Jan. 23, 2025
Mentha asiatica Boriss., a species native to Central Asia, has garnered significant attention for its diverse phytochemical profile and antimicrobial potential. This review synthesizes current knowledge on the activities of M. asiatica, focusing essential oils other bioactive constituents. The study contextualizes importance natural antimicrobials in era rising antibiotic resistance highlights plant’s traditional use ethnomedicine. main methodologies explored include gas chromatography–mass spectrometry (GC–MS) characterization various vitro assays assess efficacy against bacterial fungal pathogens. demonstrate broad spectrum activity, attributed compounds such as menthol, menthone, carvone. Other phytochemicals, including sesquiterpenes terpenoids, also contribute bioactivity. underscores potential source novel agents calls further research into mechanisms action, bioavailability, safety profiles. findings position promising candidate developing plant-based formulations, addressing critical needs healthcare food preservation.
Language: Английский
Citations
0
Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(2), P. 167 - 167
Published: Jan. 27, 2025
Background/Objectives: This study aimed to develop cinnamon bark essential oil (CEO), orange peel oil(OEO) and the combination of these two oils (OEO-CEO) loaded PLGA nanoparticles prevent dental caries investigate their effectiveness in silico vitro methods. Methods: EO were produced by single emulsion method. Detailed characterization studies performed using different methods, controlled release profile was obtained. The antibacterial activity developed formulations investigated on S. mutans L. casei strains Additionally, interaction mechanisms EOs with DNA evaluated. Results: Our findings showed that average droplet size EO-loaded varied between 243.1 ± 0.60 nm 219 4.49 nm, while PdI values 0.069 0.039 0.032 0.01. In addition, had high encapsulation efficiency (85.14% 66.28%) released active ingredient a continuous manner. Ames test genotoxicity eliminated due tests OEO-CEO-loaded effective mutans. also supported studies. Finally, it revealed potential as agents interacting DNA. Conclusions: results have be suitable nanoformulation for developing mouthwash or toothpaste prevention treatment caries.
Language: Английский
Citations
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Deleted Journal, Journal Year: 2025, Volume and Issue: 67(1)
Published: Feb. 1, 2025
Language: Английский
Citations
0
Industrial Biotechnology, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 14, 2025
Citations
0
Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(2), P. 255 - 255
Published: Feb. 14, 2025
Background/Objectives: Drug repurposing explores new applications for approved medications, such as simvastatin (SV), a lipid-lowering drug that has shown anticancer potential but is limited by solubility and side effects. This study aims to enhance SV delivery efficacy against lung cancer cells using bioactive lipid nanoparticles formulated with plant-derived monoterpenes both nanostructuring agents molecules. Methods: Lipid were produced ultrasonication characterized morphology, size, zeta potential, polydispersity index (PDI). Monoterpenes (linalool-LN-, limonene, 1,8-cineole) or Crodamol® used liquid lipids. Encapsulation efficiency (EE), release profiles, stability, biocompatibility, protein adsorption, cytotoxicity, effects evaluated. Results: The exhibited high size: 94.2 ± 0.9-144.0 2.6 nm, PDI < 0.3, potential: -4.5 0.7 -16.3 0.8 mV. of in all formulations enhanced cytotoxicity A549 cells, NLC/LN/SV showing the highest activity being chosen further investigation. Sustained over 72 h EE > 95% was observed NLC/LN/SV. SAXS/WAXS analysis revealed LN altered crystallographic structure nanoparticles. demonstrated excellent biocompatibility developed thin serum corona vitro. Cellular studies showed efficient uptake G0/G1 arrest, mitochondrial hyperpolarization, reactive oxygen species production, cell death compared free SV. more effectively inhibited migration than Conclusions: represents promising nanocarrier repurposing, combining activity, sustained stability therapy.
Language: Английский
Citations
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South African Journal of Botany, Journal Year: 2025, Volume and Issue: 179, P. 112 - 123
Published: Feb. 18, 2025
Language: Английский
Citations
0
Plants, Journal Year: 2025, Volume and Issue: 14(5), P. 705 - 705
Published: Feb. 25, 2025
Citrus x limonia is an aromatic species, known locally in Ecuador as limón mandarina or chino. In the present study, chemical composition and biological activity of essential oil isolated from this species were determined. The was extracted through hydrodistillation. enantiomeric distribution determined by gas chromatography. Antimicrobial using broth microdilution method against tree Gram-positive cocci, a bacillus, four Gram-negative bacilli, fungus, yeast. antioxidant ABTS (2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)) DPPH (2,2-diphenyl-1-picrylhydrazyl) methods. spectrophotometric used to determine anticholinesterase activity. oil, thirty-nine compounds identified, which represented 99.35% total composition. Monoterpene hydrocarbons most representative group terms number (thirteen) relative abundance (91.39%). main constituents found be limonene (57.38 ± 1.09%), γ-terpinene (13.01 0.37%), β-pinene (12.04 0.63%). Five pairs enantiomers identified fruits limonia. presented minimum inhibitory concentration 4000 μg/mL Aspergillus niger. weak per method, with SC50 1.26 mg/mL. Additionally, exhibited moderate activity, IC50 203.9 1.03 µg/mL. This study provides first comprehensive analysis activities
Language: Английский
Citations
0