Nanomaterial-Based Molecular Imaging in Cancer: Advances in Simulation and AI Integration
Biomolecules,
Journal Year:
2025,
Volume and Issue:
15(3), P. 444 - 444
Published: March 20, 2025
Nanomaterials
represent
an
innovation
in
cancer
imaging
by
offering
enhanced
contrast,
improved
targeting
capabilities,
and
multifunctional
modalities.
Recent
advancements
material
engineering
have
enabled
the
development
of
nanoparticles
tailored
for
various
techniques,
including
magnetic
resonance
(MRI),
computed
tomography
(CT),
positron
emission
(PET),
ultrasound
(US).
These
nanoscale
agents
improve
sensitivity
specificity,
enabling
early
detection
precise
tumor
characterization.
Monte
Carlo
(MC)
simulations
play
a
pivotal
role
optimizing
nanomaterial-based
modeling
their
interactions
with
biological
tissues,
predicting
contrast
enhancement,
refining
dosimetry
radiation-based
techniques.
computational
methods
provide
valuable
insights
into
nanoparticle
behavior,
aiding
design
more
effective
agents.
Moreover,
artificial
intelligence
(AI)
machine
learning
(ML)
approaches
are
transforming
enhancing
image
reconstruction,
automating
segmentation,
improving
diagnostic
accuracy.
AI-driven
models
can
also
optimize
MC-based
accelerating
data
analysis
through
predictive
modeling.
This
review
explores
latest
imaging,
highlighting
synergy
between
nanotechnology,
MC
simulations,
innovations.
By
integrating
these
interdisciplinary
approaches,
future
technologies
achieve
unprecedented
precision,
paving
way
diagnostics
personalized
treatment
strategies.
Language: Английский
Smart biomaterials in healthcare: Breakthroughs in tissue engineering, immunomodulation, patient-specific therapies, and biosensor applications
Applied Physics Reviews,
Journal Year:
2025,
Volume and Issue:
12(1)
Published: March 1, 2025
Smart
biomaterials
have
significantly
impacted
human
healthcare
by
advancing
the
development
of
medical
devices
designed
to
function
within
tissue,
mimicking
behavior
natural
tissues.
While
intelligence
has
evolved
from
inert
active
over
past
few
decades,
smart
take
this
a
step
further
making
their
surfaces
or
bulk
respond
based
on
interactions
with
surrounding
tissues,
imparting
outcomes
similar
tissue
functions.
This
interaction
helps
in
creating
stimuli-responsive
biomaterials,
which
can
be
useful
engineering,
regenerative
medicine,
autonomous
drug
delivery,
orthopedics,
and
much
more.
Traditionally,
material
engineering
focused
refining
static
properties
accommodate
them
body
without
evoking
an
immune
response,
was
major
obstacle
unrestricted
operation.
review
highlights
explains
various
approaches
currently
under
research
for
developing
that
tune
responses
bodily
factors
like
temperature,
pH,
ion
concentration
external
magnetism,
light,
conductivity.
Applications
soft
hard
4D
printing,
scaffold
design
are
also
discussed.
The
advanced
application
microfluidics,
organ-on-a-chip
models,
extensively
benefits
intrinsic
discussed
below.
elaborates
how
biomaterial
could
revolutionize
biosensor
applications,
thereby
improving
patient
care
quality.
We
delineate
limitations
key
challenges
associated
providing
insights
into
path
forward
outlining
future
directions
next-generation
will
facilitate
clinical
translation.
Language: Английский
Bio-Hybrid Films from Chirich Tuber Starch: A Sustainable Approach with Machine Learning-Driven Optimization
Sustainability,
Journal Year:
2025,
Volume and Issue:
17(5), P. 1935 - 1935
Published: Feb. 24, 2025
This
study
investigates
the
potential
of
Chirich
(Asphodelus
aestivus)
tuber,
one
Turkey’s
natural
resources,
for
sustainable
bio-hybrid
film
production.
Bio-hybrid
films
developed
from
tuber
starch
in
composite
form
with
polyvinyl
alcohol
(PVOH)
were
thoroughly
examined
their
physical,
mechanical,
and
barrier
properties.
During
production
process,
twin-screw
extrusion
hydraulic
hot
pressing
methods
employed;
films’
optical,
chemical,
performances
analyzed
through
FT-IR
spectroscopy,
water
vapor
permeability,
solubility,
mechanical
tests.
To
evaluate
durability
against
environmental
factors
model
properties,
advanced
computational
algorithms
such
as
Gradient
Boosting
Regression
(GBR),
Random
Forest
(RFR),
AdaBoost
(ABR)
utilized.
The
results
showed
that
GBR
algorithm
achieved
highest
accuracy
99.92%
R2
presented
most
robust
terms
sensitivity
to
factors.
indicate
tuber-based
exhibit
significantly
enhanced
strength
performance
compared
conventional
corn
starch-based
biodegradable
polymers.
These
superior
properties
make
them
particularly
suitable
industrial
applications
food
packaging
medical
materials,
where
durability,
moisture
resistance,
gas
characteristics
are
critical.
Moreover,
biodegradability
integration
into
circular
economy
frameworks
underscore
sustainability,
offering
a
viable
alternative
petroleum-derived
plastics.
incorporation
ML-driven
optimization
not
only
facilitates
precise
property
prediction
but
also
enhances
scalability
By
introducing
an
innovative,
data-driven
approach
material
design,
this
contributes
advancement
bio-based
polymers
applications,
supporting
global
efforts
mitigate
plastic
waste
promote
environmentally
responsible
manufacturing
practices.
Language: Английский
Analyzing the effects of recycled aggregates on the workability and mechanical characteristics of concrete through mixture design and optimization techniques
Messaouda Bensmail,
No information about this author
Rebih Zaitri,
No information about this author
Mostefa Hani
No information about this author
et al.
World Journal of Engineering,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 27, 2025
Purpose
This
paper
aims
to
report
the
results
of
an
experimental
program
using
a
statistical
modeling
technique
enhance
formulation
ordinary
concrete
with
recycled
aggregates
(RCA)
derived
from
demolition
trash
in
Biskra
region,
Algeria.
Design/methodology/approach
The
valorized
materials
consist
coarse
dry
and
presaturated
(SRCA),
available
two
granular
fractions
(3
/
8
mm
16
mm),
obtained
through
crushing
screening
operations.
These
partially
substitute
natural
(NCA).
A
three-factor
design
was
used
evaluate
effects
RCA,
SRCA
NCA
on
fresh
hardened
properties
conventional
concrete.
research
effectively
created
recognized
mathematical
models
that
most
accurately
describe
findings.
Findings
demonstrate
notably
improves
workability
due
its
presaturation,
which
reduces
water
absorption
elevates
availability
free
water.
In
contrast,
mechanical
strength
(compressive
at
14
28
days)
is
highest
when
content
maximal
(100%),
but
increasing
proportion
RCA
leads
progressive
reduction
strength.
Furthermore,
flexural
days
increases
higher
aggregates;
but,
days,
deflection
more
pronounced
combinations
high
concentration
NCA.
Originality/value
optimization
validation
confirmed
predicted
values
error
margin
under
8%,
emphasizing
feasibility
as
sustainable
construction
material.
findings
offer
significant
insights
into
effective
utilization
design,
enabling
their
incorporation
practical
applications
while
maintaining
structural
performance
sustainability.
Language: Английский
3D‐Printed Scaffolds for Cranial Bone Regeneration: A Systematic Review of Design, Materials, and Computational Optimization
Elnaz Khorasani,
No information about this author
Bahman Vahidi
No information about this author
Biotechnology and Bioengineering,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 27, 2025
ABSTRACT
Cranial
bone
defects
from
trauma,
congenital
conditions,
or
surgery
are
challenging
to
treat
due
the
skull's
limited
regeneration.
Traditional
methods
like
autografts
and
allografts
have
drawbacks,
including
donor
site
issues
poor
integration.
3D‐printed
scaffolds
provide
a
patient‐specific
alternative,
improving
regeneration
This
review
evaluates
advancements
in
for
cranial
regeneration,
focusing
on
fabrication
techniques,
material
innovations,
structural
optimization
while
assessing
their
preclinical
clinical
potential.
A
systematic
literature
search
(2014–2024)
was
conducted
using
PubMed
other
databases.
Studies
addressing
scaffold
properties
such
as
porosity,
pore
interconnectivity,
mechanical
stability
were
included,
non‐cranial
studies
excluded.
Advances
3D
printing
enabled
with
optimized
architecture
enhance
support,
nutrient
transport.
Bioceramics,
polymers,
composites
mimic
native
properties,
bioactive
coatings
further
improve
osteogenesis.
However,
translation
insufficient
customization
remain
challenges.
Further
trials
crucial
overcoming
barriers
fabrication,
bridging
gap
between
research
applications.
Language: Английский
BAYESIAN NEURAL NETWORKS FOR PROBABILISTIC MODELING OF THERMAL DYNAMICS IN MULTISCALE TISSUE ENGINEERING SCAFFOLDS
Journal of Thermal Biology,
Journal Year:
2025,
Volume and Issue:
130, P. 104134 - 104134
Published: May 1, 2025
Language: Английский
Economic, technological and environmental drivers of the circular economy in the European Union: a panel data analysis
Environmental Sciences Europe,
Journal Year:
2025,
Volume and Issue:
37(1)
Published: May 24, 2025
Language: Английский
Integration of AI-Based Nano Synergy in Bayesian Uncertainty Quantification for Advanced Engineering Design
S. N. Deepa,
No information about this author
Dr.Meenakshipatil,
No information about this author
Padmini Kaji
No information about this author
et al.
Nanotechnology Perceptions,
Journal Year:
2024,
Volume and Issue:
unknown, P. 77 - 89
Published: Dec. 1, 2024
The
advancement
in
artificial
intelligence
and
nanotechnology
has
provided
new
solutions
for
tackling
problems
enhanced
engineering
design.
This
research
focuses
on
both
AI
assisted
observational
methodologies
Bayesian
uncertainty
quantification
(BUQ)
improving
the
predictive
models,
material
properties,
design
procedures.
Four
complex
techniques
of
estimating
managing
are
following:
Neural
Networks
(BNN),
Gaussian
Processes
(GP),
Monte
Carlo
Dropout
(MCD),
Ensemble
Learning
(EL).
Numerical
studies
revealed
that
forecast
accuracy
proposed
framework
is
94.6%
with
BNN
93.1%
GP,
which
makes
excellent
improvements
over
prior
arts
up
to
15%
quantification.
Besides,
computational
resources
less
by
20%
EL
compared
standalone
approaches,
while
incorporation
nanoscale
information
increase
AT
RT
17%.
To
demonstrate
AI-driven
BUQ
addresses
limitations
existing
a
comparative
discussion
provided.
results
reinforce
its
viability
providing
sustainable
efficient
under
conditions
risk.
work
may
be
used
as
platform
subsequent
synergies
between
AI,
nanotechnology,
advanced
materials
systems
drive
progress
well
Language: Английский