Frontiers in Chemistry,
Journal Year:
2025,
Volume and Issue:
12
Published: Jan. 15, 2025
Microorganisms
are
becoming
resistant
to
drugs
and
antimicrobials,
making
it
a
significantly
critical
global
issue.
Nosocomial
infections
resulting
in
alarmingly
increasing
rates
of
morbidity
mortality.
Plant
derived
compounds
hold
numerous
antimicrobial
properties,
them
very
capable
source
counteract
microbial
strains.
Syzygium
aromaticum
(Clove)
extract
has
been
proven
by
studies
contain
active
ingredients
that
demonstrate
antibacterial,
antifungal,
antioxidant,
insecticidal
properties.
It
also
used
historically
for
its
pain
relief
especially
tooth
ache.
Clove
nanoparticle
synthesis
is
promising
method
combining
therapeutics
with
metals
at
nanoscale.
Such
nanostructured
systems
combination
the
heterocyclic
antibiotic
clarithromycin
could
potentiate
action
plant
extracts,
decrease
drug
side
effects
improve
activity.
In
this
study,
clove
(C)
was
successfully
synthesize
silver
nanoparticles
(AgNP)
create
AgNPC
AgNPCA
(A
=
clarithromycin).
The
two
underwent
different
analytical
methods
consisting
SEM,
EDS,
DLS,
UV-vis,
FTIR
XRD.
These
were
against
variety
10
pathogens
exhibited
good
intermediate
antibacterial
resulted
better
properties
smaller
size.
This
study
demonstrates
potential
mediated
AgNP
without
clarithromycin.
ABSTRACT
Phytochemicals
are
bioactive
compounds
found
in
plants
that
play
a
key
role
promoting
health
and
preventing
diseases.
Present
fruits,
vegetables,
grains,
seed
oils,
these
considered
safe
for
consumption
due
to
the
co‐evolution
adaptation
between
mammals
plants.
Due
their
wide‐ranging
biological
effects,
they
have
attracted
considerable
research
interest.
This
comprehensive
review
explores
mechanisms
of
action,
benefits,
applications
dietary
phytochemicals,
with
particular
focus
on
groups
such
as
polyphenols,
flavonoids,
carotenoids.
Research
shows
phytochemicals
interact
nuclear
membrane
receptors,
influence
metabolic
pathways,
affect
epigenetic
modifications.
Our
highlights
broad
range
activities
compounds,
including
antioxidant,
antibacterial,
anti‐inflammatory,
anti‐diabetic,
anticancer
all
which
contribute
health‐promoting
properties.
Clinical
evidence
supports
prevention
management
diseases
cardiovascular
disorders,
conditions,
cancer,
diets
rich
being
linked
lower
risk
disease.
also
at
cutting
edge
food
preservation,
supplements,
emerging
medical
treatments.
Additionally,
we
identified
advancements
extraction
identification
techniques,
particularly
metabolomics,
further
enhance
areas.
Despite
promising
challenges
bioavailability,
regulatory
barriers,
need
robust
clinical
trials
persist.
However,
innovative
delivery
systems
like
nanoparticles,
liposomes,
encapsulation
offer
potential
solutions
bioavailability
by
improving
absorption
stability.
The
concludes
emphasizing
personalized
nutrition
combination
therapies
benefits
while
stressing
methods,
trials,
bioavailability.
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(9), P. 4949 - 4949
Published: May 1, 2024
Antimicrobial
resistance
(AMR)
poses
an
emanating
threat
to
humanity’s
future.
The
effectiveness
of
commonly
used
antibiotics
against
microbial
infections
is
declining
at
alarming
rate.
As
a
result,
morbidity
and
mortality
rates
are
soaring,
particularly
among
immunocompromised
populations.
Exploring
alternative
solutions,
such
as
medicinal
plants
iodine,
shows
promise
in
combating
resistant
pathogens.
Such
antimicrobials
could
effectively
inhibit
proliferation
through
synergistic
combinations.
In
our
study,
we
prepared
formulation
consisting
Aloe
barbadensis
Miller
(AV),
Thymol,
iodine
(I2),
polyvinylpyrrolidone
(PVP).
Various
analytical
methods
including
SEM/EDS,
UV-vis,
Raman,
FTIR,
XRD
were
carried
out
verify
the
purity,
composition,
morphology
AV-PVP-Thymol-I2.
We
evaluated
inhibitory
effects
this
10
selected
reference
strains
using
impregnated
sterile
discs,
surgical
sutures,
gauze
bandages,
face
masks,
KN95
masks.
antimicrobial
properties
AV-PVP-Thymol-I2
assessed
disc
diffusion
comparison
with
two
common
antibiotics.
25-month-old
exhibited
slightly
lower
zones,
indicating
changes
sustained-iodine-release
reservoir.
Our
findings
confirm
potent
antifungal
antibacterial
agent
strains,
demonstrating
strong
action
on
cotton
These
results
enable
potential
use
promising
wound
spray-on
contact-killing
agent.
Medicinski Glasnik,
Journal Year:
2025,
Volume and Issue:
22(1)
Published: Jan. 17, 2025
<p><strong>Aim</strong>
Magnetic
fields
affect
all
living
things,
which
is
why
they
are
the
subject
of
extensive
research
around
world.
The
aim
this
study
was
to
investigate
effects
different
levels
static
magnetic
field
on
chemical
behaviours
aqueous
extract
<em>Syzygium
aromaticum</em>
L
and
their
effect
selective
oral
pathogenic
bacteria.&nbsp;<br
/><strong>Methods</strong>
This
utilized
locally
manufactured
dipolar
with
strengths
between
1200
3200
Gauss,
measured
by
a
Sylocimol
Residence
magnetizer.
Gram
positive
G
(+)
<em>Streptococcus
viridans</em>
negative
(G-)
<em>Porphyromonas
gingivalis</em>
strains
were
used
in
studies
antimicrobial
properties
<em>S.
extract.
Tests
carried
out
using
clove
essential
component
(eugenol)
its
functionalized
evaluate
various
bacterial
inhibitions
establish
whether
there
synergistic
subjected
field.&nbsp;<br
/><strong>Results</strong>
Polyphenol
extraction
increased
eugenol
content.
analytical
method's
reliability
confirmed
chromatograms
acetate
standards,
demonstrating
good
separation
compounds.
selectivity
method
guaranteed
purity
index
peaks.
showed
properties.
activity
against
two
strains.
Cell
viability
changed
at
intensities,
inhibition
zone
for
<em>P.
significantly
due
prolonged
exposure.
&nbsp;<br
/><strong>Conclusion</strong>
magnetized
inhibits
both
(-)
bacteria
when
combined
extract.</p>
Biotech Studies,
Journal Year:
2025,
Volume and Issue:
34(1), P. 34 - 51
Published: Feb. 11, 2025
This
study
examined
the
antioxidant
capacities
of
rosemary
and
thyme
leaf
powders
their
impact
on
lipid
oxidation
in
minced
beef
during
refrigerated
storage.
Five
types
were
prepared:
Control
(meat
without
additives),
TLP
0.2
+
0.2%
powder),
0.4
0.4%
RLP
powder)
(Meat
stored
at
4oC
for
seven
days.
Results
revealed
that
exhibited
higher
(P
<
0.05)
phenol
(398.75
mg
GAE/g),
flavonoid
(172.30
QE/g)
vitamin
C
(82.05
mg/g)
contents
than
(297.61
mgGAE/g,
65.72
mgQE/g
52.56
mg/g,
respectively).
Extracts
demonstrated
antiradical
activity
TLP.
During
day
zero
storage,
there
was
no
significant
effect
beef.
However,
three,
both
significantly
reduced
control
group.
Also
seven,
greatly
>
compared
to
Thus,
application
could
serve
as
effective
preservatives,
inhibiting
meat
products.
JSFA reports,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 21, 2025
Abstract
Background
This
study
is
devoted
to
determining
the
chemical
composition
of
essential
oils
obtained
from
13
wild
populations
thyme
(
Thymus
vulgaris
L.)
and
14
winter
savory
Satureja
montana
Solsonès
region
Catalonia,
Spain.
The
were
by
hydrodistillation
using
a
Clevenger
apparatus,
volatile
compounds
identified
gas
chromatography
coupled
with
mass
spectrometry.
Results
Twenty‐six
detected
in
samples,
including
linalool,
(Z)‐sabinene
hydrate,
terpinen‐4‐ol,
α‐terpenyl
acetate.
In
contrast,
19
carvacrol,
ρ‐cymene,
γ‐terpinene
as
major
components.
results
facilitated
comparative
analyses
among
enabling
assessment
differences
related
geographical
location
growing
conditions.
Significant
variability
profile
samples
was
observed,
underscoring
influence
several
factors.
Notably,
observed
increase
linalool
content
northwestern
areas
region,
evident
both
thyme,
attributed
discernible
position
or
climatic
division
effect.
For
instance,
ranged
3.9%
southern
high
75.8%
certain
northern
populations.
Similarly,
varied
significantly,
reaching
up
36.7%
some
compared
lower
values
such
9.6%.
Conclusion
information
holds
significance
for
selection
suitable
prospective
applications
pharmaceutical,
cosmetic,
gastronomic
industries.
