Three-Dimensional Bioprinting: A Comprehensive Review for Applications in Tissue Engineering and Regenerative Medicine

Bioengineering, Journal Year: 2024, Volume and Issue: 11(8), P. 777 - 777

Published: July 31, 2024

Since three-dimensional (3D) bioprinting has emerged, it continuously to evolved as a revolutionary technology in surgery, offering new paradigms for reconstructive and regenerative medical applications. This review highlights the integration of 3D printing, specifically bioprinting, across several surgical disciplines over last five years. The methods employed encompass recent literature focusing on innovations applications 3D-bioprinted tissues and/or organs. findings reveal significant advances creation complex, customized, multi-tissue constructs that mimic natural tissue characteristics, which are crucial interventions patient-specific treatments. Despite technological advances, paper introduces discusses challenges remain, such vascularization bioprinted tissues, with host tissue, long-term viability concludes while holds substantial promise transforming practices enhancing patient outcomes, ongoing research, development, clear regulatory framework essential fully realize potential future clinical

Language: Английский

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Advancements in 3D printing techniques for biomedical applications: a comprehensive review of materials consideration, post processing, applications, and challenges

Discover Materials, Journal Year: 2024, Volume and Issue: 4(1)

Published: Oct. 3, 2024

Language: Английский

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Regenerative Medicine in Plastic Surgery: The Role of Stem Cells and Bioprinting

Regenesis repair rehabilitation., Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

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Advances in Bioprinting with a Focus on Self-Healing Hydrogels Bio-inks for Soft Tissue Regeneration: Innovations, Applications, and Future Perspectives

Materials Today Communications, Journal Year: 2025, Volume and Issue: unknown, P. 112094 - 112094

Published: March 1, 2025

Language: Английский

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Using ChatGPT to Write a Literature Review on Autologous Fat Grafting

Journal of Plastic Reconstructive & Aesthetic Surgery, Journal Year: 2025, Volume and Issue: 105, P. 292 - 304

Published: April 17, 2025

Language: Английский

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Acellular Scaffolds for Muscle Regeneration: Advances and Challenges

Advances in Wound Care, Journal Year: 2025, Volume and Issue: unknown

Published: May 9, 2025

Significance: Volumetric muscle loss is defined as composite of mass. Severe injuries result in permanent functional impairment. Treatment options are limited. Tissue engineering techniques utilizing scaffolds offer promise a potential therapy. Recent Advances: Emerging strategies, including bioactive molecules and growth factors biocompatible scaffolds, may promote regeneration following severe injury. In this context, can act drug-delivery device, provide guidance to cells supporting matrix, slowly release healing. Critical Issues: Scaffolds engraftment ability tissue injured beds remain Tuning optimizing scaffold fiber diameter, alignment, cellular cues, factor delivery, porosity will be important reconstituting skeletal loss. Future Directions: Our mechanistic understanding interactions between biomimetic host still evolving, future research identify regeneration.

Language: Английский

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A comprehensive review of the educational, clinical and rehabilitative applications of 3D printing technology in hand surgery

Plastic and Aesthetic Research, Journal Year: 2024, Volume and Issue: 11(3)

Published: Aug. 29, 2024

With the rapid development of 3D printing (3DP) technology in both educational and perioperative settings, a thorough evaluation latest literature is warranted. This semi-systematic review explores current educational, clinical, rehabilitative applications 3DP hand surgery. In student trainee education improved with use inexpensive, accessible models for anatomy surgical simulation, demonstrating an enhanced understanding spatial relationships increased confidence skills. Patient consent can be patient-specific models. Studies showed that led to higher patient comprehension satisfaction during consenting process. Patient-specific also offer more comprehensive preoperative planning, cutting guides facilitate precise techniques. Clinical outcomes indicated reduced operative times radiation exposure, along accuracy. Additionally, enables creation cost-effective implants precisely conform each patient's anatomy. For purposes, make splints have potential reduce costs improve compliance. Preliminary data comfort functional 3D-printed splints. Overall, mixed on benefits surgery; however, many studies show promising results. As becomes streamlined equipment less expensive, its will continue expand, future research needed. Future should focus long-term clinical cost-effectiveness fully ascertain efficacy value

Language: Английский

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Fabrication Method for Shape-Controlled 3D Tissue Using High-Porosity Porous Structure

Bioengineering, Journal Year: 2024, Volume and Issue: 11(2), P. 160 - 160

Published: Feb. 5, 2024

Shape-controlled 3D tissues resemble natural living in human and animal bodies are essential materials for developing improving technologies regenerative medicine, drug discovery, biological robotics. In previous studies, shape-controlled were fabricated using scaffold structures or bioprinting techniques. However, controlling the shape of without leaving non-natural inside tissue efficiently fabricating them remains challenging. this paper, we propose a novel method free flexible high-porosity porous structure (HPPS). The HPPS consisted micromesh with pore sizes 14.87 ± 1.83 μm, lattice widths 2.24 0.10 thicknesses 9.96 0.92 porosity 69.06 3.30%, an I-shaped microchamber depth 555.26 11.17 μm. U-87 glioma cells cultured 48 h. After cultivation, was released within few seconds while maintaining its I-shape. Specific chemicals, such as proteolytic enzymes, not used. Moreover, viability composed above 90%. Therefore, proposed fabrication is recommended applying significant stresses to cells.

Language: Английский

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3D bioprinting: a review and potential applications for Mohs micrographic surgery

Archives of Dermatological Research, Journal Year: 2024, Volume and Issue: 316(5)

Published: May 2, 2024

Language: Английский

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APLICAÇÕES DA TECNOLOGIA 3D NA CIRURGIA PLÁSTICA RECONSTRUTIVA

International Journal of Health Management Review, Journal Year: 2024, Volume and Issue: 10(1), P. e357 - e357

Published: Aug. 16, 2024

Introdução: A tecnologia tridimensional (3D) tem desempenhado um papel crescente na cirurgia plástica reconstrutiva, oferecendo uma variedade de ferramentas e técnicas inovadoras para melhorar os resultados cirúrgicos. Essas aplicações incluem desde o planejamento pré-operatório até a simulação procedimentos fabricação dispositivos médicos personalizados. Objetivos: Este estudo visa explorar as diversas formas como 3D está sendo utilizada destacando seus benefícios desafios, além investigar da reconstrutiva identificar desafios limitações associados à integração desse tipo prática clínica. Métodos: Foi conduzida revisão literatura científica atual sobre uso focalizando últimos três anos. pesquisa foi utilizando base dados MEDLINE, acessada por meio plataforma PubMed, descritores em inglês garantir inclusão estudos globais análise final. dos incluiu síntese informações diferentes dessa tecnologia, suas vantagens limitações. Resultados: As analisadas incluíram imagens tridimensionais preciso, complexos modelos impressos enxertos próteses personalizadas. O cirúrgico assistido pode precisão estéticos, reduzindo tempo riscos pacientes. observado também que impressão facilitado criação sob medida, promovendo abordagem mais individualizada eficaz reconstrução. Conclusão: desempenhando cada vez importante significativas termos cirúrgico, Entretanto, custos, acesso com sistemas saúde ainda precisam ser discutidos. desenvolvimento contínuo adoção generalizada dessas inovações têm potencial pacientes submetidos esse cirurgia, qual anseia modernas.

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