Clinical application and original scientific justification for the rehabilitation of patients with mandibular bone atrophy (reference review)
Oral and General Health,
Journal Year:
2025,
Volume and Issue:
5(3), P. 105 - 121
Published: Jan. 2, 2025
In
presenting
the
following
justifications,
we
assert
that
tooth
loss
is
primary
etiological
factor
in
development
of
jawbone
atrophy,
which
influences
topographic
features
canal
system,
with
potential
degenerative
changes
its
morphological
variants.
Using
bibliosemantic
method,
a
comprehensive
analysis
anatomical
variability
left
and
right
mandibular
canals
bone
atrophy
caused
by
masticatory
teeth
was
conducted
presented
this
manuscript.
The
findings
have
not
only
theoretical
significance
but
also
practical
importance
for
clinical
dentistry,
as
they
may
serve
basis
developing
new,
effective
methods
to
predict
treat
pathological
conditions
tissue,
specifically
restoration
properties.
Language: Английский
Exploring the link between genetic disorders and early-onset periodontal disease
Ola Jamal Balkhair,
No information about this author
Rasha Ahmed Badahdah,
No information about this author
Abdulaziz Alajmi
No information about this author
et al.
International Journal of Community Medicine and Public Health,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 29, 2025
Periodontal
disease
is
a
complex,
multifactorial
condition
characterized
by
chronic
inflammation
and
progressive
destruction
of
the
tooth-supporting
structures.
Among
its
various
forms,
early-onset
periodontitis
particularly
aggressive
often
associated
with
genetic
predispositions.
Genetic
epigenetic
factors
play
pivotal
roles
in
shaping
host
susceptibility
to
this
influencing
immune
responses,
inflammatory
regulation,
tissue
homeostasis.
Single-nucleotide
polymorphisms
(SNPs)
genes
encoding
cytokines,
such
as
interleukin-1β
tumor
necrosis
factor-alpha,
are
linked
heightened
amplifying
damage
accelerating
progression.
Additionally,
like
TLR2
TLR4
impair
microbial
recognition,
promoting
dysbiosis.
Epigenetic
modifications,
including
DNA
methylation
histone
acetylation,
further
modulate
gene
expression,
contributing
dynamic
interplay
between
predispositions
environmental
smoking
or
poor
oral
hygiene.
Emerging
research
has
also
highlighted
markers
human
leukocyte
antigen
(HLA)
alleles
matrix
metalloproteinase
(MMP)
variants
predictors
severity
therapeutic
outcomes.
These
insights
have
driven
development
targeted
therapies,
inhibitors
pro-inflammatory
mediators,
MMP
inhibitors,
potential
miRNA-based
interventions.
High-throughput
technologies,
genome-wide
association
studies
(GWAS),
expanded
understanding
pathways
involved
periodontal
disease.
advances
enable
earlier
detection
personalized
treatment
strategies,
offering
mitigate
progression
reduce
burden
severe
periodontitis.
The
integration
into
clinical
practice
marks
significant
step
toward
precision
medicine,
providing
framework
for
tailored
prevention
interventions
aimed
at
improving
patient
Future
must
continue
explore
these
mechanisms
uncover
novel
biomarkers
refine
approaches
Language: Английский
Bone Metabolism and Dental Implant Insertion as a Correlation Affecting on Marginal Bone Remodeling: Texture Analysis and the New Corticalization Index, Predictor of Marginal Bone Loss—3 Months of Follow-Up
Journal of Clinical Medicine,
Journal Year:
2024,
Volume and Issue:
13(11), P. 3212 - 3212
Published: May 30, 2024
Background/Objectives:
The
general
condition
of
implantology
patients
is
crucial
when
considering
the
long-
and
short-term
survival
dental
implants.
aim
research
was
to
evaluate
correlation
between
new
corticalization
index
(CI)
patients’
condition,
its
impact
on
marginal
bone
loss
(MBL)
leading
implant
failure,
using
only
radiographic
(RTG)
images
a
pixel
level.
Method:
Bone
near
neck
examined,
texture
features
were
analyzed.
Statistical
analysis
includes
simple
regression
where
coefficient
(CC)
R2
calculated.
Detected
relationships
assumed
be
statistically
significant
p
<
0.05.
Statgraphics
Centurion
version
18.1.12
(Stat
Point
Technologies,
Warrenton,
VA,
USA)
used
conduct
statistical
analyses.
Results:
revealed
MBL
after
3
months
BMI,
PTH,
TSH,
Ca2+
level
in
blood
serum,
phosphates
vitamin
D.
A
also
observed
CI
D,
LDL,
HDL,
triglycerides
day
surgery.
After
observation
period,
correlated
with
triglycerides.
Conclusion:
results
confirm
that
corresponds
MBL.
patient’s
has
an
metabolism
around
Implant
insertion
should
considered
if
patient
not
stable.
However,
yet
been
fully
investigated.
Further
studies
are
necessary
check
categorize
Language: Английский
Nonlinear Finite Element Analysis of Bone–Implant Contact in Three Short Dental Implant Models with Varying Osseointegration Percentages
Oral,
Journal Year:
2024,
Volume and Issue:
4(4), P. 505 - 524
Published: Oct. 22, 2024
Objectives:
Dental
implants
have
become
a
cornerstone
of
restorative
dentistry,
providing
long-lasting
method
for
tooth
replacement.
The
degree
osseointegration
has
significant
effect
on
biomechanical
stability
at
the
bone–implant
contact
(BIC),
determining
continued
efficacy
these
implants.
However,
exact
consequences
changing
levels
different
implant
designs,
especially
in
bones
with
variable
densities,
are
not
well
known.
Methods:
This
study
used
3D
finite
element
analysis
(FEA)
to
look
performance
three
short
dental
implants:
BioMet
3iT3,
Straumann®
Standard
Plus
Short-Regular
Neck
(SPS-RN),
and
Short-Wide
(SPS-WN).
paper
tested
four
stages
osseointegration:
25%,
50%,
75%,
100%
both
high-density
(bone
type
III)
low-density
IV)
cancellous
bone.
It
also
created
examined
realistic
CAD
models
under
static
occlusal
loading
conditions
assess
stress
distribution
major
strains
contact.
Results:
discovered
that
as
increases,
von
Mises
principal
go
down
significantly
all
types.
SPS-WN
had
lowest
strain
values,
bone
low
density.
These
reductions
demonstrate
increased
mechanical
interface
becomes
more
capable
dispersing
stresses,
minimizing
potential
localized
deformation
resorption.
Conclusions:
results
highlight
importance
achieving
optimum
reduce
increase
lifespan
performed
better
tests
than
others,
when
were
ideal.
makes
it
great
choice
clinical
applications
need
long-term
success.
Language: Английский
Nonlinear Finite Element Analysis of Bone-Implant Contact in Three Short Dental Implant Models with Varying Osseointegration Percentages
Published: Aug. 29, 2024
Background/Objectives:
Dental
implants
have
become
a
cornerstone
of
restorative
dentistry,
providing
long-lasting
method
for
tooth
replacement.
The
level
osseointegration
has
big
impact
on
the
biomechanical
stability
at
bone-implant
contact
(BIC),
which
determines
how
long
these
will
work.
However,
exact
consequences
changing
levels
different
implant
designs,
especially
in
bones
with
variable
densities,
are
not
well
known.
Three
short
dental
were
tested
this
study:
BioMet
3iT3,
Straumann®
Standard
Plus
Short
Regular
Neck
(SPS-RN),
and
Short-Wide
(SPS-WN).
3D
finite
element
analysis
(FEA)
was
used
to
look
they
worked
biomechanically.
This
paper
tests
four
stages
osseointegration:
25%,
50%,
75%,
100%
both
high-density
(Bone
Type
III)
low-density
IV)
cancellous
bone.
It
also
created
examined
realistic
CAD
models
under
static
occlusal
loading
conditions
assess
stress
distribution
major
strains
contact.;
Results:
study
discovered
that
as
osteointegration
increases,
von
Mises
principal
go
down
significantly
all
types.
SPS-WN
had
lowest
strain
values,
bone
low
density.
These
reductions
demonstrate
increased
mechanical
inter-face
becomes
more
capable
dispersing
stresses,
minimizing
potential
localized
deformation
resorption.;
Conclusions:
results
highlight
importance
achieving
optimum
reduce
increase
lifespan
implants.
type
performed
better
than
others,
when
ideal.
makes
it
great
choice
clinical
applications
need
long-term
success.Keywords:
x
Language: Английский