Advances in medical diagnosis, treatment, and care (AMDTC) book series,
Journal Year:
2024,
Volume and Issue:
unknown, P. 265 - 290
Published: Dec. 17, 2024
Synthetic
biology
and
artificial
intelligence
are
ushering
in
a
new
era
of
healthcare.
In
the
specific
context
bioengineering,
organoids,
brain-computer
interfaces,
ethical
considerations
particularly
salient.
Challenges
such
as
data
inadequacy,
unintended
bias
can
undermine
reliability
fairness
decision
making.
Additionally,
cultural
barriers
concerns
related
to
nonmaleficence,
autonomy,
justice
must
be
carefully
considered.
To
fully
realize
benefits
this
technological
synergy,
multidisciplinary
approach
is
necessary,
involving
scientists,
engineers,
ethicists,
policymakers.
Transparent
accountable
AI
systems
essential
mitigate
biases,
protect
privacy,
avoid
consequences.
By
proactively
addressing
developing
robust
regulatory
frameworks,
we
harness
power
these
technologies
for
betterment
humanity.
Journal of Materials Science,
Journal Year:
2024,
Volume and Issue:
59(31), P. 14095 - 14140
Published: July 30, 2024
Abstract
Electrospun
nanofibers
have
gained
prominence
as
a
versatile
material,
with
applications
spanning
tissue
engineering,
drug
delivery,
energy
storage,
filtration,
sensors,
and
textiles.
Their
unique
properties,
including
high
surface
area,
permeability,
tunable
porosity,
low
basic
weight,
mechanical
flexibility,
alongside
adjustable
fiber
diameter
distribution
modifiable
wettability,
make
them
highly
desirable
across
diverse
fields.
However,
optimizing
the
properties
of
electrospun
to
meet
specific
requirements
has
proven
be
challenging
endeavor.
The
electrospinning
process
is
inherently
complex
influenced
by
numerous
variables,
applied
voltage,
polymer
concentration,
solution
flow
rate,
molecular
weight
polymer,
needle-to-collector
distance.
This
complexity
often
results
in
variations
nanofibers,
making
it
difficult
achieve
desired
characteristics
consistently.
Traditional
trial-and-error
approaches
parameter
optimization
been
time-consuming
costly,
they
lack
precision
necessary
address
these
challenges
effectively.
In
recent
years,
convergence
materials
science
machine
learning
(ML)
offered
transformative
approach
electrospinning.
By
harnessing
power
ML
algorithms,
scientists
researchers
can
navigate
intricate
space
more
efficiently,
bypassing
need
for
extensive
experimentation.
holds
potential
significantly
reduce
time
resources
invested
producing
wide
range
applications.
Herein,
we
provide
an
in-depth
analysis
current
work
that
leverages
obtain
target
nanofibers.
examining
work,
explore
intersection
ML,
shedding
light
on
advancements,
challenges,
future
directions.
comprehensive
not
only
highlights
processes
but
also
provides
valuable
insights
into
evolving
landscape,
paving
way
innovative
precisely
engineered
various
Graphical
abstract
Macromolecular Rapid Communications,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 2, 2025
Abstract
Electrospinning
is
increasingly
used
as
a
staple
technology
for
the
fabrication
of
nano‐
and
micro‐fibers
different
materials.
Most
processes
utilize
direct
current
(DC)
electrospinning,
multitude
DC‐electrospinning
tools
ranging
from
research
to
commercial
production
systems
currently
available.
Yet,
there
are
numerous
studies
performed
on
electrospinning
techniques
utilizing
non‐DC,
periodic
electric
fields,
or
alternating
(AC)
electrospinning.
Those
demonstrate
strong
potential
AC‐electrospinning
sustainable
various
nanofibrous
materials
structures.
Although
tremendous
progress
achieved
in
development
over
last
10
years,
this
technique
remains
uncommon.
This
paper
reviews
concepts,
instrumentation,
technology.
The
main
focus
review
most
studied,
“electric
wind”
driven
tentatively
named
field
(AFES).
latter
term
emphasizes
role
AC
field's
confinement
fiber‐generating
electrode
absence
counter
such
an
system.
synopses
AFES
process
parameters,
spinneret
designs,
benefits
obstacles,
advancements
electrospun
nano/micro‐fibrous
materials/structures
their
applications
given,
future
directions
discussed.
Nanomaterials,
Journal Year:
2025,
Volume and Issue:
15(4), P. 290 - 290
Published: Feb. 13, 2025
Gum
Arabic
(GA),
or
acacia
gum,
refers
to
the
dried
exudate
produced
by
certain
Acacia
trees.
GA
is
composed
mainly
of
a
mixture
polysaccharides
and
glycoproteins,
with
proportions
that
can
slightly
differ
from
one
species
another.
It
commonly
utilized
in
food
pharmaceutical
industries
as
stabilizer
an
emulsifier
owing
its
biocompatibility,
hydrophilicity,
antibacterial
properties.
In
addition,
be
manipulated
it
possesses
many
functional
groups
used
grafting,
cross-linking,
chemical
modifications
add
new
feature
developed
material.
this
review,
we
highlight
recent
GA-based
formulations,
including
nanoparticles,
hydrogels,
nanofibers,
membranes,
scaffolds,
their
possible
applications
tissue
regeneration,
cancer
therapy,
wound
healing,
biosensing,
bioimaging,
packaging,
antimicrobial
antifouling
membranes.
Frontiers in Cardiovascular Medicine,
Journal Year:
2025,
Volume and Issue:
12
Published: Feb. 27, 2025
Despite
advancements
in
surgical
techniques,
many
patients
born
with
congenital
heart
defects
(CHD)
require
repeated
reinterventions
due
to
the
limitations
of
materials
used
cardiac
surgery
(CCS).
Traditional
biogenic
polymers,
such
as
bovine
or
equine
pericardium,
are
prone
calcification,
have
limited
durability,
and
fail
adapt
growth
infants.
This
study
aims
address
these
challenges
by
investigating
bacterial
cellulose
(BC)
a
promising
material
for
CCS.
Variability
patch
quality
from
previous
studies
was
addressed
refining
production
protocol
taking
advantage
optical
density
(OD)
measurements.
After
72
h
incubation,
patches
were
harvested
tested
mechanically
burst
pressure
uniaxial
strain
testing.
BC's
biomechanical
properties
further
explored
modifying
nutrient
concentrations,
creating
different
media
groups
(N10,
N30,
N50).
Hybrid
combining
BC
electrospun
polyurethane
(ESP-PU)
developed
using
specially
designed
3D-printed
flask
ensure
uniform
coating
integration.
The
initial
concentration
significantly
influenced
yield
rate,
static
cultures
outperforming
shaken
ones.
Nutrient-enriched
N50)
produced
greater
elasticity
strength
compared
standard
C-Medium,
stiffness
correlating
concentration.
Inflation
tests
showed
that
N10
N30
samples
withstood
higher
pressures
than
N50,
which,
despite
being
stiffer,
performed
worse
under
rapid
inflation.
All
samples,
however,
maintained
above
physiological
levels.
Scanning
electron
microscopy
analysis
confirmed
effective
PU
fibres
without
altering
fibre
orientation
activity.
demonstrated
resistance
1,400
mmHg.
can
be
tailored,
combination
ESP-PU,
an
innovative
hybrid
produced,
positioning
biomaterial
future
CCS
implant
development.
BioTech,
Journal Year:
2025,
Volume and Issue:
14(1), P. 23 - 23
Published: March 19, 2025
Ischemic
heart
disease
(IHD)
is
the
leading
cause
of
mortality
worldwide,
underscoring
urgent
need
for
innovative
therapeutic
strategies.
The
cardiac
extracellular
matrix
(ECM)
undergoes
extreme
transformations
during
IHD,
adversely
influencing
heart's
structure,
mechanics,
and
cellular
signaling.
Researchers
investigating
regenerative
capacity
diseased
have
turned
their
attention
to
exploring
modulation
ECM
improve
outcomes.
In
this
review,
we
thoroughly
examine
current
state
knowledge
regarding
its
potential
in
ischemic
myocardium.
We
begin
by
providing
an
overview
fundamentals
ECM,
focusing
on
structural,
functional,
regulatory
mechanisms
that
drive
modulation.
Subsequently,
ECM's
interactions
within
both
chronically
acutely
infarcted
myocardium,
emphasizing
key
components
roles
modulating
angiogenesis.
Finally,
discuss
recent
ECM-based
approaches
biomedical
engineering,
different
types
scaffolds
as
delivery
tools
compositions,
conclude
with
future
directions
research.
By
harnessing
these
emerging
therapies,
aim
contribute
development
novel
modalities
IHD.
Journal of Applied Polymer Science,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 3, 2025
ABSTRACT
Electrospinning
has
been
studied
to
deposit
polylactic
acid
(PLA)
nanofibers
on
complex
coronary
stent
geometries.
The
rheological
properties
of
PLA
with
two
molecular
weights
were
analyzed
in
various
solvents,
including
chloroform,
acetone,
dichloromethane,
and
dimethylformamide,
determine
the
entanglement
concentration.
High
weight
dissolved
a
2:1
v/v
chloroform:
acetone
was
suitable
form
bead‐free
uniform
morphology.
A
response
surface
methodology
implemented
evaluate
electrospinning
parameters
(concentration,
flow
rate,
voltage).
thin
film
mat
examined
by
scanning
electron
microscopy
(SEM)
size
fibers
fiber
diameter
distribution.
concentration
8%
w/v,
voltage
15
kV,
rate
0.02
mL/min
produced
an
average
around
491
±
150
nm
flat
surface.
Additionally,
deposited
geometry
using
rotary
motor,
resulting
measuring
approximately
817
388
nm.
Advanced Science,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 7, 2025
Abstract
The
incidence
and
burden
of
skin
wounds,
especially
chronic
complex
have
a
profound
impact
on
healthcare.
Effective
wound
healing
strategies
require
multidisciplinary
approach,
advances
in
materials
science
bioengineering
paved
the
way
for
development
novel
dressing.
In
this
context,
electrospun
nanofibers
can
mimic
architecture
natural
extracellular
matrix
provide
new
opportunities
healing.
Inspired
by
bioelectric
phenomena
human
body,
nanofibrous
scaffolds
with
electroactive
characteristics
are
gaining
widespread
attention
gradually
emerging.
To
end,
review
first
summarizes
basic
process
healing,
causes
current
status
clinical
treatment,
highlighting
urgency
importance
dressings.
Then,
biological
effects
electric
fields,
preparation
materials,
manufacturing
techniques
(EEN)
discussed.
latest
progress
EEN
enhancing
is
systematically
reviewed,
mainly
including
treatment
monitoring.
Finally,
scaffold
to
enhance
emphasized,
challenges
prospects
summarized.
Royal Society of Chemistry eBooks,
Journal Year:
2024,
Volume and Issue:
unknown, P. 214 - 250
Published: Nov. 15, 2024
The
development
of
biocompatible
nanofibres
through
electrospinning
is
a
promising
method
for
engineers
in
the
biomedical
field.
existing
coating
technologies
medical
field
have
various
limitations,
and
more
investigations
are
needed
to
improve
their
biocompatibility,
controlled
release
properties,
mechanical
strength.
Designing
new
materials
that
can
interact
efficiently
with
biological
systems
offer
numerous
functional
advantages
major
challenge
device
manufacturing
tissue
engineering.
This
chapter
reviews
approaches
used
create
nanofibres,
including
design,
fabrication
functionalization.
applications
these
coatings
also
reviewed.
Furthermore,
we
discuss
methods,
used,
key
parameters
impact
fibre
morphology
physiochemical
properties.
Moreover,
incorporation
bioactive
elements
drugs
into
therapeutic
explored.
biologically
friendly
be
an
effective
approach
improving
coatings.
Such
enhance
properties
such
as
drug
delivery,
regeneration,
implant
integration,
offering
enormous
potential
patient
welfare.
Future
research
areas
include
investigating
use
advanced
procedures
enhanced
control
over
nanofibre
composition
design
fabrication.
Bioengineering,
Journal Year:
2024,
Volume and Issue:
11(6), P. 549 - 549
Published: May 29, 2024
Cardiovascular
disease
(CVD)
is
one
of
the
leading
causes
death
globally.
Currently,
clinical
diagnosis
CVD
primarily
relies
on
electrocardiograms
(ECG),
which
are
relatively
easier
to
identify
compared
other
diagnostic
methods.
However,
ensuring
accuracy
ECG
readings
requires
specialized
training
for
healthcare
professionals.
Therefore,
developing
a
system
based
ECGs
can
provide
preliminary
results,
effectively
reducing
workload
staff
and
enhancing
diagnosis.
In
this
study,
deep
neural
network
with
cross-stage
partial
cross-attention-based
transformer
used
develop
an
ECG-based
decision
system.
To
accurately
represent
characteristics
ECG,
employed
extract
embedding
features.
This
capture
leverage
information
from
different
stages,
feature
extraction
process.
distill
features,
model,
known
its
robust
scalability
that
enables
it
process
data
sequences
lengths
complexities,
meaningful
resulting
in
more
accurate
outcomes.
The
experimental
results
showed
challenge
scoring
metric
proposed
approach
0.6112,
outperforms
others.
useful
