Impact of Convulsive Maternal Seizures on Fetus Dynamics DOI Open Access
Milan Toma, Jonathan Mayer,

Molly Bekbolatova

et al.

International Journal for Numerical Methods in Biomedical Engineering, Journal Year: 2024, Volume and Issue: 41(1)

Published: Dec. 25, 2024

ABSTRACT The study findings demonstrate that the amniotic fluid plays an important role in protecting fetus during convulsive maternal seizures. was found to be effective buffer, significantly reducing transfer of kinetic energy these events. This highlights sufficient protection provided by such circumstances. research conducted using a model simulates complex interactions between pregnant woman's anatomy, uterus, and immersed fluid. Key parameters as speed, acceleration, Euler angles were captured sensors used input for computational simulations. results showed oscillatory movement, which is characteristic seizure, placenta exhibit variable kinematics relative uterus. Despite variations, significant protective buffer. discovery seizures provides valuable insights obstetricians. It can help managing patient care pregnancy complications, emphasizing importance fetal protection.

Language: Английский

A biomechanical comparative study of passive stomach tissue from pigs and humans DOI Creative Commons
Clarissa S. Holzer-Stock, Anna Pukaluk, Christian Viertler

et al.

Acta Biomaterialia, Journal Year: 2025, Volume and Issue: unknown

Published: May 1, 2025

Language: Английский

Citations

0
Post-Trauma Fetal Care Using Computational Analysis in Prenatal Surgical Guidance DOI Creative Commons

Atieh Dehghani Ashkezari,

Molly Bekbolatova,

Jonathan Mayer

et al.

Surgeries, Journal Year: 2024, Volume and Issue: 5(3), P. 682 - 693

Published: Aug. 17, 2024

The purpose of this research is to explore the biomechanical consequences maternal injuries on fetal movements. Additionally, aims comprehend relationship between these and movement within amniotic sac understand extent which fluid can provide protection during severe injuries. focus potential impact could have surgical procedures preventative strategies. Using advanced computational simulations, study investigates how various influence behavior subsequent stress exerted development. findings suggest that induce stress, primarily affecting posterior regions fetus umbilical cord, depending boundary initial conditions. This associated with displacement sac. While provides a certain level protection, its limitations become apparent These insights implications for field surgery, particularly procedures. They underscore need improved protective measures development personalized obstetric neonatal care Moreover, highlights simulations in aiding surgeons. more accurate understanding critical areas procedures, thereby enhancing precision safety operations.

Language: Английский

Citations

1
Implications of compressive loading of the stomach wall: Interplay between mechanical deformation and microstructure DOI Creative Commons
Clarissa S. Holzer-Stock, Anna Pukaluk, Christian Viertler

et al.

Acta Biomaterialia, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

Citations

1
Mechanoadaptive Bioelectronics for Deep Tissue Sensing DOI Open Access
Xueyang Ren,

Yuehui Yuan,

Jianqing Li

et al.

Chinese Journal of Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 20, 2024

Comprehensive Summary Deep‐tissue physiological signals are critical for accurate disease diagnosis. Current clinical equipment, however, often falls short of enabling continuous, long‐term monitoring. Wearable and implantable flexible electronics offer a promising avenue addressing this limitation, allowing in vivo signal collection paving the way early diagnosis personalized treatment. A major challenge lies ensuring that these devices seamlessly integrate with diverse microenvironments throughout human body. Mechanoadaptive bioelectronics is emerging as key solution to optimize acquisition device robustness. This review provides comprehensive overview characteristics various organs types they generate. Furthermore, it explores recent advancements mechanoadaptive bioelectronics, systematically categorizes their strategies, underscores potential revolutionize healthcare. Finally, we delve into ongoing challenges field highlight directions advance adaptability further. Key Scientists In 2017, researchers developed an ionic skin enhanced mechanical compatibility through strain‐hardening properties. [1] Three years later, neural interface platform called adaptive self‐healing electronic epineurium (A‐SEE) was reported. [2] minimized stress on tissue by dynamically relaxing stress. 2021, hydrogel hybrid probe tracking isolated neuroelectric activity, optogenetics, behavioral studies circuits. also utilized hydration‐induced softening minimize foreign body response. [3] same year, shape‐adaptive imager Kirigami design proposed. [4] following morphing (MorphE) reported, which exhibited attractive viscoelasticity minimal growing nerve during implantation. [5] 2023, standardized tissue‐electronic developed, can be implanted minimally invasive cardiac procedures rapidly beating heart. [6] Recently, needle‐like microfiber based biphasic liquid metal created. reach target site simply puncturing enable multifunctional sensing. [7] At about time, amalgamated living synthetic components studying treating inflammatory disease. [8] enables real‐time digital updates potentially treatment non‐resolving inflammation, enlightening new generation bioelectronics.

Language: Английский

Citations

1
Effect of Compressive Strain Rates on Viscoelasticity and Water Content in Intact Porcine Stomach Wall Tissues DOI

Vijay Shashank Udayamohan,

Achu G. Byju,

Jason L. Harris

et al.

Journal of Biomechanical Engineering, Journal Year: 2024, Volume and Issue: 147(2)

Published: Nov. 9, 2024

Laparoscopic staplers are used extensively to seal and transect tissue. These devices compress tissue between the stapler jaws achieve a desired compressed thickness in preparation for stapling. The extent rate of compression dependent on surgeon technique, characteristics, type, all which can impact stapling outcomes such as bleeding, staple line leaks, healing. Historically, surgeons have relied their experience, training, tactile feedback from device optimize In recent years, transition electromechanical robotic has greatly impacted available surgeon. This raises new questions about optimal rates resultant forces. study quantifies transmural biomechanics porcine stomach wall. Multirate indentation tests were observe effects viscoelastic behavior during indentation, stress relaxation, unconstrained recovery. Results show that wall demonstrates higher relaxation (88% versus 80%) greater strain recovery (52% 47%) when indented at high (37.5%/s) slow (7.5%/s). Additionally, water content analysis was fluid flow away regions. Unindented regions found compared (78% 75%). data generated this may be enable development constitutive models tissue, turn inform control algorithms drive compressive surgical devices.

Language: Английский

Citations

0
Impact of Convulsive Maternal Seizures on Fetus Dynamics DOI Open Access
Milan Toma, Jonathan Mayer,

Molly Bekbolatova

et al.

International Journal for Numerical Methods in Biomedical Engineering, Journal Year: 2024, Volume and Issue: 41(1)

Published: Dec. 25, 2024

ABSTRACT The study findings demonstrate that the amniotic fluid plays an important role in protecting fetus during convulsive maternal seizures. was found to be effective buffer, significantly reducing transfer of kinetic energy these events. This highlights sufficient protection provided by such circumstances. research conducted using a model simulates complex interactions between pregnant woman's anatomy, uterus, and immersed fluid. Key parameters as speed, acceleration, Euler angles were captured sensors used input for computational simulations. results showed oscillatory movement, which is characteristic seizure, placenta exhibit variable kinematics relative uterus. Despite variations, significant protective buffer. discovery seizures provides valuable insights obstetricians. It can help managing patient care pregnancy complications, emphasizing importance fetal protection.

Language: Английский

Citations

0