Chemosensors, Journal Year: 2025, Volume and Issue: 13(6), P. 194 - 194
Published: May 22, 2025
Titanium dioxide (TiO2) is one of the most widely produced nanomaterials. Many products contain nanoparticles because they have various technological, medical, and economic benefits. However, presence in environment has a negative impact on public health. Due to TiO2 NPs food, food packaging, drinking water, can easily enter human gastrointestinal tract (GIT), which includes environments with different pH values. These changes affect stability, dispersion, toxicity Our experiments aimed monitor effect incubated at similar GIT values DNA structure. damage was monitored using biosensor biosensing approach electrochemical voltammetric detection. Cyclic voltammetry (CV) detected DNA/GCE biosensors up 10%. The best way genotoxicity structure approach, redox indicator current response by differential pulse (DPV) 47.6%. highest observed for guanine residues 8.0. results were confirmed UV–vis spectrophotometry hyperchromic bathochromic spectral shifts.
Language: Английский