Ginger: a total-scale analysis of the scientific literature on a widely used spice and phytotherapeutic DOI
Maima Matin, Andy Wai Kan Yeung, Tanuj Joshi

et al.

Animal Science Papers and Reports, Journal Year: 2024, Volume and Issue: 42(4), P. 349 - 364

Published: Dec. 1, 2024

Abstract Ginger ( Zingiber officinale ) has been utilized for medicinal and culinary purposes thousands of years. Its extensive history showcases diverse uses health benefits. In this study, we conducted a thorough analysis the scientific literature landscape surrounding ginger using bibliometric techniques, aiming to explore recurring topics, trends, influential contributors, main journals publishing ginger-related research. Utilizing Web Science (WoS) Core Collection, identified 9,881 relevant papers published up October 4, 2023. The revealed an exponential growth in both publication citation counts since mid-2000s. Key phytochemical constituents, including gingerols shogaols, emerged as focal points most frequently mentioned medical condition term was ‘Cancer’ (n = 577), followed by ‘Obesity’ 180) ‘COVID’ 176). Journals such Journal Ethnopharmacology Food Chemistry played leading roles sharing articles. Our study offers broad overview research, highlighting significant increase scholarly interest globally. This not only contributes quantitative insights existing but also provides roadmap future investigations on ginger. positions promising candidate addressing contemporary challenges, inviting further exploration clinical studies.

Language: Английский

Unravelling the diversity and utilisation of emerging spices and herbs in Malawi: a pathway to diversified nutrition and community health DOI
Dickson Mgangathweni Mazibuko,

Ruth Nyambura Maru,

Hiroko Gono

et al.

Transactions of the Royal Society of South Africa, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 18

Published: Feb. 6, 2025

Language: Английский

Citations

0
Exploring the innovation landscape of ginger: Insights from patent documentation analysis DOI Creative Commons
Maima Matin, Bhupinder Kapoor,

Monica Gulati

et al.

Current Research in Biotechnology, Journal Year: 2025, Volume and Issue: unknown, P. 100299 - 100299

Published: May 1, 2025

Language: Английский

Citations

0
Ginger (Zingiber officinale) dietary supplementation in mice regulates liver antioxidant defense systems in a dose- and age-dependent DOI Creative Commons
Maima Matin, Kamil Wysocki, Jarosław Olav Horbańczuk

et al.

Frontiers in Pharmacology, Journal Year: 2025, Volume and Issue: 16

Published: May 15, 2025

Introduction Oxidative stress and impaired antioxidant defenses contribute significantly to liver dysfunction, particularly with aging. This study evaluated the dose- age-dependent effects of dietary ginger ( Zingiber officinale ) supplementation on defense systems in mice. Methods Male Swiss Webster mice aged 3, 6, 12 months (n = 48 per age group) received standard feed or supplemented either 0.6% 1.8% dried powder for 3 months. Liver tissue was analyzed multiple parameters, including DPPH radical scavenging activity, total capacity, vitamin C levels, phenolic content, superoxide dismutase (SOD) malondialdehyde (MDA) reduced glutathione (GSH) concentrations. Results The results demonstrated significant declines several parameters control animals, SOD activity. Ginger produced differential based both dose age. While 3-month-old showed decreased supplementation, 6- 12-month-old exhibited increased Higher-dose (1.8%) enhanced GSH levels across all groups, being most pronounced older activity remained unaffected by groups. MDA were mice, smaller, dose-dependent but non-significant reductions Discussion These findings demonstrate that ginger’s are age-dependent, generally stronger beneficial observed at higher doses animals. variations emphasize importance personalized strategies provide a foundation future research into molecular mechanisms underlying effects.

Language: Английский

Citations

0
Bioactive Compounds in Osteoarthritis: Molecular Mechanisms and Therapeutic Roles DOI Open Access
Ahmed Maouche, Karim Boumédiene, Catherine Baugé

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(21), P. 11656 - 11656

Published: Oct. 30, 2024

Osteoarthritis (OA) is the most common and debilitating form of arthritis. Current therapies focus on pain relief efforts to slow disease progression through a combination drug non-drug treatments. Bioactive compounds derived from plants show significant promise due their anti-inflammatory, antioxidant, tissue-protective properties. These natural can help regulate inflammatory processes metabolic pathways involved in OA, thereby alleviating symptoms potentially slowing progression. Investigating efficacy these agents treating osteoarthritis addresses growing demand for health solutions creates new opportunities managing this increasingly prevalent age-related condition. The aim review provide an overview use some bioactive modulating associated pain.

Language: Английский

Citations

1
Phytosome-Encapsulated 6-Gingerol- and 6-Shogaol-Enriched Extracts from Zingiber officinale Roscoe Protect against Oxidative Stress-Induced Neurotoxicity DOI Creative Commons
Nootchanat Mairuae, Parinya Noisa, Nut Palachai

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(24), P. 6046 - 6046

Published: Dec. 22, 2024

The rising prevalence of neurodegenerative disorders underscores the urgent need for effective interventions to prevent neuronal cell death. This study evaluates neuroprotective potential phytosome-encapsulated 6-gingerol- and 6-shogaol-enriched extracts from Zingiber officinale Roscoe (6GS), bioactive compounds renowned their antioxidant anti-inflammatory properties. novel phytosome encapsulation technology employed enhances bioavailability stability these compounds, offering superior therapeutic compared conventional formulations. Additionally, investigates role phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt)-signaling pathway, a key mediator effects 6GS. Neurotoxicity was induced in SH-SY5Y cells (a human neuroblastoma line) using 200 μM hydrogen peroxide (H2O2), following pretreatment with 6GS at concentrations 15.625 31.25 μg/mL. Cell viability assessed via MTT assay alongside evaluations reactive oxygen species (ROS), enzyme activities (superoxide dismutase [SOD], catalase [CAT], glutathione peroxidase [GSH-Px]), oxidative stress markers (malondialdehyde [MDA]), molecular mechanisms involving PI3K/Akt apoptotic factors (B-cell lymphoma-2 [Bcl-2] caspase-3), inflammatory (tumor necrosis factor-alpha [TNF-α]). results demonstrated that significantly improved viability, reduced ROS, MDA, TNF-α, caspase-3 levels, enhanced activities. Furthermore, treatment upregulated PI3K, Akt, Bcl-2 expression while suppressing activation. Activation pathway by led phosphorylated Akt-mediated upregulation Bcl-2, promoting survival attenuating inflammation. Moreover, inhibited ROS generation, further mitigating neurotoxicity. These findings suggest 6GS, which through activation exhibits significant Incorporating into functional foods or dietary supplements could offer promising strategy addressing neuroinflammation associated diseases.

Language: Английский

Citations

1
Ginger: a total-scale analysis of the scientific literature on a widely used spice and phytotherapeutic DOI
Maima Matin, Andy Wai Kan Yeung, Tanuj Joshi

et al.

Animal Science Papers and Reports, Journal Year: 2024, Volume and Issue: 42(4), P. 349 - 364

Published: Dec. 1, 2024

Abstract Ginger ( Zingiber officinale ) has been utilized for medicinal and culinary purposes thousands of years. Its extensive history showcases diverse uses health benefits. In this study, we conducted a thorough analysis the scientific literature landscape surrounding ginger using bibliometric techniques, aiming to explore recurring topics, trends, influential contributors, main journals publishing ginger-related research. Utilizing Web Science (WoS) Core Collection, identified 9,881 relevant papers published up October 4, 2023. The revealed an exponential growth in both publication citation counts since mid-2000s. Key phytochemical constituents, including gingerols shogaols, emerged as focal points most frequently mentioned medical condition term was ‘Cancer’ (n = 577), followed by ‘Obesity’ 180) ‘COVID’ 176). Journals such Journal Ethnopharmacology Food Chemistry played leading roles sharing articles. Our study offers broad overview research, highlighting significant increase scholarly interest globally. This not only contributes quantitative insights existing but also provides roadmap future investigations on ginger. positions promising candidate addressing contemporary challenges, inviting further exploration clinical studies.

Language: Английский

Citations

1