Clinical characteristics of COVID-19 in children: a large multicenter study from Iran DOI Creative Commons

Azin Hajialibeig,

Mohammad Reza Navaeifar,

Amir-Hassan Bordbari

et al.

Frontiers in Pediatrics, Journal Year: 2024, Volume and Issue: 12

Published: July 23, 2024

Introduction During the COVID-19 pandemic, pediatric cases typically exhibit milder symptoms and lower mortality rates. However, delay in vaccination poses major risks for children. This multicenter study aimed to comprehensively analyze demographic characteristics, clinical features, disease severity, risk factors ICU admission Iran. Materials methods observational enrolled children aged 0–21 years with confirmed or probable diagnoses, referred from selected hospitals across 17 counties Mazandaran province, Iran, between February 19 August 14, 2021. Patients were categorized into mild, moderate, severe, critical based on radiographic criteria. Data extracted medical records analyzed using statistical methods. Logistic regression analysis was performed identify associated severity. Results Among 1,031 included study, 61 diagnosed MIS-C. The distribution of patients by severity 156 671 204 severe/critical cases. Age significantly differed groups ( P < 0.001), 55.19% over 5 54% being male. 11.44% had underlying diseases. Fever (71.97%) most common symptom, followed cough (34.43%) dyspnea (24.83%). Within inpatient group, 19.77% required admission, 0.91% mortality, including 3 MIS-C Children diseases, gastrointestinal symptoms, obesity 4.16, 3.10-, 2.17-times higher likelihood respectively. Conclusion Our emphasized importance recognizing symptoms. While fever, cough, prevailed, rates relatively low. comorbidities, obesity, linked stressing early intervention. BMI also impacted rate. Vaccination targeted interventions are essential protecting vulnerable easing healthcare strain.

Language: Английский

Comparison of clinical characteristics and disease burden of febrile seizures in children with and without COVID-19 DOI Creative Commons
Zhongli Jiang,

Cuiyun Fang,

Fengyimei Peng

et al.

BMC Pediatrics, Journal Year: 2024, Volume and Issue: 24(1)

Published: May 13, 2024

Abstract Background Febrile seizures (FS) are the most common seizure disorder in children and a neurologic complication with coronavirus disease 2019 (COVID-19). This study aimed to identify differences clinical characteristics burden between FS without COVID-19. Materials methods We conducted retrospective analysis of medical data at our hospital from December July 2023, focusing on hospitalized patients under age 14 diagnosed who underwent COVID-19 polymerase chain reaction (PCR) testing. Descriptive statistics variance were employed compare non-COVID-19 groups terms burden. Results A total 514 included, 106 testing positive for 408 negative. Patients older (34.87 ± 6.16 vs. 28.61 11.35 months, P < 0.001) had higher proportion males (79.2% 62.3%, = 0.001). The group longer durations (4.57 4.38 3.22 2.91 min, 0.006) more complex (25.5% 15.9%, 0.022). Laboratory tests showed lower lymphocyte counts (1.87 1.48 2.75 1.51 × 103/µL, creatine kinase levels (158.49 82.89 110.89 56.11 U/L, No significant found costs, length hospitalization, intensive care unit admissions. Conclusion Clinicians should be knowledgeable about distinct Despite features, prognosis remains favorable does not require excessive intervention. Ongoing monitoring research needed fully understand impact optimize management strategies.

Language: Английский

Citations

0
Clinical characteristics of COVID-19 in children: a large multicenter study from Iran DOI Creative Commons

Azin Hajialibeig,

Mohammad Reza Navaeifar,

Amir-Hassan Bordbari

et al.

Frontiers in Pediatrics, Journal Year: 2024, Volume and Issue: 12

Published: July 23, 2024

Introduction During the COVID-19 pandemic, pediatric cases typically exhibit milder symptoms and lower mortality rates. However, delay in vaccination poses major risks for children. This multicenter study aimed to comprehensively analyze demographic characteristics, clinical features, disease severity, risk factors ICU admission Iran. Materials methods observational enrolled children aged 0–21 years with confirmed or probable diagnoses, referred from selected hospitals across 17 counties Mazandaran province, Iran, between February 19 August 14, 2021. Patients were categorized into mild, moderate, severe, critical based on radiographic criteria. Data extracted medical records analyzed using statistical methods. Logistic regression analysis was performed identify associated severity. Results Among 1,031 included study, 61 diagnosed MIS-C. The distribution of patients by severity 156 671 204 severe/critical cases. Age significantly differed groups ( P &lt; 0.001), 55.19% over 5 54% being male. 11.44% had underlying diseases. Fever (71.97%) most common symptom, followed cough (34.43%) dyspnea (24.83%). Within inpatient group, 19.77% required admission, 0.91% mortality, including 3 MIS-C Children diseases, gastrointestinal symptoms, obesity 4.16, 3.10-, 2.17-times higher likelihood respectively. Conclusion Our emphasized importance recognizing symptoms. While fever, cough, prevailed, rates relatively low. comorbidities, obesity, linked stressing early intervention. BMI also impacted rate. Vaccination targeted interventions are essential protecting vulnerable easing healthcare strain.

Language: Английский

Citations

0