Nano Biomedicine and Engineering, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 1, 2024
Language: Английский
Clinics and Practice, Journal Year: 2025, Volume and Issue: 15(1), P. 17 - 17
Published: Jan. 14, 2025
Background: Artificial intelligence (AI) has emerged as a transformative technology in healthcare, with its integration into cardiac surgery offering significant advancements precision, efficiency, and patient outcomes. However, comprehensive understanding of AI’s applications, benefits, challenges, future directions is needed to inform safe effective implementation. Methods: A systematic review was conducted following PRISMA guidelines. Literature searches were performed PubMed, Scopus, Cochrane Library, Google Scholar, Web Science, covering publications from January 2000 November 2024. Studies focusing on AI applications surgery, including risk stratification, surgical planning, intraoperative guidance, postoperative management, included. Data extraction quality assessment using standardized tools, findings synthesized narratively. Results: total 121 studies included this review. demonstrated superior predictive capabilities machine learning models outperforming traditional scoring systems mortality complication prediction. Robotic-assisted enhanced precision minimized trauma, while computer vision augmented cognition improved guidance. Postoperative showed potential predicting complications, supporting monitoring, reducing healthcare costs. challenges such data quality, validation, ethical considerations, clinical workflows remain barriers widespread adoption. Conclusions: the revolutionize by enhancing decision making, accuracy, Addressing limitations related bias, regulatory frameworks essential for Future research should focus interdisciplinary collaboration, robust testing, development transparent ensure equitable sustainable surgery.
Language: Английский
Citations
1
Antioxidants, Journal Year: 2025, Volume and Issue: 14(2), P. 183 - 183
Published: Feb. 4, 2025
B-lymphocyte-induced maturation protein 1 (Blimp-1) is a transcription factor that, among other functions, modulates metabolism and helps to regulate antioxidant pathways, which important in the context of chronic inflammatory diseases like diabetes, cardiovascular disease, autoimmune disease. In immune cell function, Blimp-1 has modulatory role orchestration metabolic reprogramming as promoter anti-inflammatory cytokines, including IL-10, responsible for modulating oxidative stress homeostasis. Moreover, also key aspects, such glycolysis fatty acid oxidation, reactive oxygen species levels, well tissue protection. This review depicts an regulator defenses anti-inflammation suggests that could serve therapeutic target dysregulation conditions. The modulation diabetic coronary heart disease atherosclerosis alleviate stress, augment protection tissues, improve outcomes. potential development new treatments these conditions lies synergy between regulation therapies, are future directions may be pursued. emphasizes Blimp-1's emerging importance novel pathogenesis diseases, providing opportunities intervention.
Language: Английский
Citations
0
International Journal of Nanomedicine, Journal Year: 2025, Volume and Issue: Volume 20, P. 3445 - 3470
Published: March 1, 2025
Advances in nanotechnology have opened new avenues for precision therapy, personalized medicine, and multifunctional theranostics atherosclerosis (AS). This review provides a comprehensive overview of the role nanoparticles (NPs) medicine AS, discussing their applications, challenges, future prospects. The first analyzes current treatment landscape AS outlines potential biological targets therapy. Various nanocarriers, including organic, inorganic, hybrid systems, are evaluated therapeutic potential, with focus on targeted drug delivery, anti-inflammatory vascular repair, plaque stabilization, lipid clearance. Additionally, explores NP preparation methods, emphasizing strategies to enhance loading, stability, controlled release. Finally, translational challenges NP-based therapies, biocompatibility, large-scale production, regulatory hurdles, clinical implementation, critically analyzed. Future directions highlight importance interdisciplinary collaboration technological innovation advancing nanoparticle-based AS.
Language: Английский
Citations
0
Published: Jan. 1, 2025
Language: Английский
Citations
0
Nano Biomedicine and Engineering, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 1, 2024
Language: Английский
Citations
2