Non-Thermal Atmospheric Pressure Plasma as an Adjunct to Intestinal Anastomosis: A Pilot Study on Preventing Anastomotic Leaks DOI Creative Commons

Mario Betancourt-Ángeles,

R. López‐Callejas,

Guillermo Berrones-Stringel

et al.

Life, Journal Year: 2024, Volume and Issue: 14(11), P. 1450 - 1450

Published: Nov. 8, 2024

Anastomotic leaks remain a significant challenge in intestinal surgery, often leading to severe complications. This study investigated novel approach enhance anastomotic healing and reduce the risk of by combining traditional suturing stapling techniques with non-thermal atmospheric pressure plasma (NTAPP) application. NTAPP, cold generated through ionization ambient air, has been shown possess antimicrobial, hemostatic, wound-healing properties. NTAPP promotes sterilization, coagulation, tissue regeneration generating reactive oxygen nitrogen species, potentially strengthening union. pilot evaluated efficacy three patients undergoing anastomosis. Following standard surgical procedure, was applied directly site. Postoperative outcomes were monitored for six months, including rates. Preliminary results demonstrated promising outcomes. All exhibited successful sealing anastomosis, no evidence leakage during follow-up period, providing reassurance confidence potential sutures, staples, NTAPP. These findings suggest that can significantly improve safety surgeries reducing incidence leaks. While further research larger sample is necessary confirm these initial findings, this provide strong foundation exploring as valuable adjunct conventional preventing innovative could postoperative complications, patient outcomes, overall quality care surgery.

Language: Английский

Non-Thermal Atmospheric Pressure Plasma as an Adjunct to Intestinal Anastomosis: A Pilot Study on Preventing Anastomotic Leaks DOI Creative Commons

Mario Betancourt-Ángeles,

R. López‐Callejas,

Guillermo Berrones-Stringel

et al.

Life, Journal Year: 2024, Volume and Issue: 14(11), P. 1450 - 1450

Published: Nov. 8, 2024

Anastomotic leaks remain a significant challenge in intestinal surgery, often leading to severe complications. This study investigated novel approach enhance anastomotic healing and reduce the risk of by combining traditional suturing stapling techniques with non-thermal atmospheric pressure plasma (NTAPP) application. NTAPP, cold generated through ionization ambient air, has been shown possess antimicrobial, hemostatic, wound-healing properties. NTAPP promotes sterilization, coagulation, tissue regeneration generating reactive oxygen nitrogen species, potentially strengthening union. pilot evaluated efficacy three patients undergoing anastomosis. Following standard surgical procedure, was applied directly site. Postoperative outcomes were monitored for six months, including rates. Preliminary results demonstrated promising outcomes. All exhibited successful sealing anastomosis, no evidence leakage during follow-up period, providing reassurance confidence potential sutures, staples, NTAPP. These findings suggest that can significantly improve safety surgeries reducing incidence leaks. While further research larger sample is necessary confirm these initial findings, this provide strong foundation exploring as valuable adjunct conventional preventing innovative could postoperative complications, patient outcomes, overall quality care surgery.

Language: Английский

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