Associations of Dietary Index for Gut Microbiota and Flavonoid Intake With Female Infertility in the United States DOI Creative Commons
Di Xiao, Xiang Sun, Weidong Li

et al.

Food Science & Nutrition, Journal Year: 2025, Volume and Issue: 13(4)

Published: March 26, 2025

This study aimed to investigate the associations between a dietary index for gut microbiota (DI-GM), flavonoid intake, and female infertility, while exploring age-specific differences in these relationships identify potential strategies infertility prevention. cross-sectional focused on participants aged 18-45 years, with data obtained from 2017-2018 cycle of National Health Nutrition Examination Survey (NHANES). Weighted multivariable logistic regression models were employed examine DI-GM, self-reported infertility. Age-stratified analyses performed evaluate whether varied across reproductive life stages. Higher DI-GM scores significantly associated reduced risk (aOR = 0.30, 95% CI: 0.13-0.71, p 0.006), strongest protective effects observed women < 35 years (Q3: aOR 0.13, 0.03-0.58, 0.007; Q4: 0.27, 0.09-0.77, 0.015). Beneficial also showed effect 0.75, 0.57-0.98, 0.036). Among ≥ moderate intake (Q2) significant inverse association 0.19, 0.06-0.66, 0.009). Our findings reveal novel evidence that higher are linked lower patterns observed. younger (< years), was years. These underscore personalized targeting composition as cost-effective approaches prevention management different

Language: Английский

Associations of Dietary Index for Gut Microbiota and Flavonoid Intake With Female Infertility in the United States DOI Creative Commons
Di Xiao, Xiang Sun, Weidong Li

et al.

Food Science & Nutrition, Journal Year: 2025, Volume and Issue: 13(4)

Published: March 26, 2025

This study aimed to investigate the associations between a dietary index for gut microbiota (DI-GM), flavonoid intake, and female infertility, while exploring age-specific differences in these relationships identify potential strategies infertility prevention. cross-sectional focused on participants aged 18-45 years, with data obtained from 2017-2018 cycle of National Health Nutrition Examination Survey (NHANES). Weighted multivariable logistic regression models were employed examine DI-GM, self-reported infertility. Age-stratified analyses performed evaluate whether varied across reproductive life stages. Higher DI-GM scores significantly associated reduced risk (aOR = 0.30, 95% CI: 0.13-0.71, p 0.006), strongest protective effects observed women < 35 years (Q3: aOR 0.13, 0.03-0.58, 0.007; Q4: 0.27, 0.09-0.77, 0.015). Beneficial also showed effect 0.75, 0.57-0.98, 0.036). Among ≥ moderate intake (Q2) significant inverse association 0.19, 0.06-0.66, 0.009). Our findings reveal novel evidence that higher are linked lower patterns observed. younger (< years), was years. These underscore personalized targeting composition as cost-effective approaches prevention management different

Language: Английский

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