Gels,
Journal Year:
2024,
Volume and Issue:
10(11), P. 693 - 693
Published: Oct. 25, 2024
Hydrogels
are
known
for
their
high
water
retention
capacity
and
biocompatibility
have
become
essential
materials
in
tissue
engineering
drug
delivery
systems.
This
review
explores
recent
advancements
hydrogel
technology,
focusing
on
innovative
types
such
as
self-healing,
tough,
smart,
hybrid
hydrogels,
each
engineered
to
overcome
the
limitations
of
conventional
hydrogels.
Self-healing
hydrogels
can
autonomously
repair
structural
damage,
making
them
well-suited
applications
dynamic
biomedical
environments.
Tough
designed
with
enhanced
mechanical
properties,
enabling
use
load-bearing
cartilage
regeneration.
Smart
respond
external
stimuli,
including
changes
pH,
temperature,
electromagnetic
fields,
ideal
controlled
release
tailored
specific
medical
needs.
Hybrid
made
from
both
natural
synthetic
polymers,
combine
bioactivity
resilience,
which
is
particularly
valuable
complex
tissues.
Despite
these
innovations,
challenges
optimizing
biocompatibility,
adjusting
degradation
rates,
scaling
up
production
remain.
provides
an
in-depth
analysis
emerging
technologies,
highlighting
transformative
potential
while
outlining
future
directions
development
applications.
Expert Opinion on Drug Delivery,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 29, 2025
Transdermal
patches
offer
a
unique
advantage
by
providing
extended
therapeutic
benefits
while
maintaining
stable
plasma
drug
concentration.
The
efficacy
and
safety
of
depend
significantly
on
their
ability
to
adhere
the
skin,
feature
influenced
various
external
internal
factors.
review
primarily
focuses
fundamental
aspects
adhesion
in
transdermal
patches,
including
basic
information
about
underlying
principles
adhesion,
delivery,
characteristics
pressure
sensitive
adhesives
(PSAs),
issues,
impact
factors,
strategies
improve
patch
relevant
molecular
mechanisms.
development
with
sufficient
for
consistent
delivery
remains
challenging
task.
Challenges
stem
from
complex
interplay
among
PSAs,
permeation
enhancers,
active
pharmaceutical
ingredients
(APIs),
other
excipients
current
compositions,
further
complicated
variations
arising
dermatological
These
intricacies
impede
effectiveness
patches.
Progress
exploration
new
PSA
polymers,
conjunction
innovative
is
crucial
establishing
an
optimal
equilibrium
between
utilization
rate,
drug-loading,
release,
thus
effectively
addressing
challenges
related
adhesion.
Advanced Healthcare Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 3, 2025
Abstract
Skin
photoaging
is
a
problem
worldwide,
clinically
often
accompanied
by
collagen
decline,
increased
wrinkles,
loss
of
skin
elasticity,
structurally
weakened
skin,
and
other
complications,
which
urgently
demand
effective
treatment
strategies.
The
biosafety
efficacy
single‐function
therapies
for
repairing
are
still
challenging
clinical
medicine
today.
At
present,
numerous
studies
report
that
the
wet
adhesive
proteins
driven
from
marine
organisms
play
critical
role
in
biomedical
material
field,
particularly
aquatic
environments.
In
this
study,
natural
recombinant
protein‐based
coating
scallop
byssal
protein
prepared
to
investigate
cellular
mechanism
accelerating
repair
UVB‐induced
mouse
model.
vitro
experiments
demonstrate
safety
its
enhancing
cell
adhesion,
spreading,
proliferation,
migration.
Additionally,
effectively
scavenges
reactive
oxygen
species,
promotes
expression
adhesion
molecules
anti‐apoptotic
proteins,
inhibits
inflammatory
responses.
animal
tests,
exhibited
remarkable
adsorption
properties,
showing
significant
potential
situ
regenerative
therapy,
as
evidenced
ability
protect
against
oxidative
stress.
These
findings
suggest
Sbp9
Δ
provides
simple,
safe,
innovative
strategy
treating
photoaging.
Small Methods,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 5, 2025
Abstract
Intelligent
electronic
skin
aims
to
mimic,
enhance,
and
even
surpass
the
functions
of
biological
skin,
enabling
artificial
systems
sense
environmental
stimuli
interact
more
naturally
with
humans.
In
healthcare,
intelligent
is
revolutionizing
diagnostics
personalized
medicine
by
detecting
early
signs
diseases
programming
exogenous
for
timely
intervention
on‐demand
treatment.
This
review
discusses
latest
progress
in
bioinspired
its
application
healthcare.
First,
strategies
development
simulate
or
human
are
discussed,
focusing
on
basic
characteristics,
as
well
sensing
regulating
functions.
Then,
applications
health
monitoring
wearable
therapies
illustrating
potential
provide
warning
Finally,
significance
bridging
gap
between
emphasized
challenges
future
perspectives
summarized.
Biomimetics,
Journal Year:
2025,
Volume and Issue:
10(2), P. 108 - 108
Published: Feb. 12, 2025
Chronic
wounds
pose
a
significant
healthcare
challenge
due
to
their
risk
of
severe
complications,
necessitating
effective
management
strategies.
Bioresorbable
materials
have
emerged
as
an
innovative
solution,
offering
advantages
such
eliminating
the
need
for
secondary
surgical
removal,
reducing
infection
risks,
and
enabling
time-delayed
drug
delivery.
This
review
examines
recent
advancements
in
bioresorbable
wound
healing
materials,
focusing
on
systematic
systems
incorporating
electrical
stimulation,
delivery
technologies
accelerate
tissue
repair.
The
discussion
encompasses
fundamental
principles
including
resorption
mechanisms
key
properties,
alongside
preclinical
applications
that
demonstrate
practical
potential.
Critical
challenges
impeding
widespread
adoption
are
addressed,
prospects
integrating
these
cutting-edge
into
clinical
practice
outlined.
Together,
insights
underscore
promise
revolutionizing
chronic
care.
Biomimetics,
Journal Year:
2025,
Volume and Issue:
10(5), P. 270 - 270
Published: April 27, 2025
With
the
recent
development
of
advanced
industries,
in
addition
to
simple
abrasions,
demand
for
wound
dressing
is
gradually
increasing
fields
such
as
diabetes
care.
Factors
affecting
healing
include
pH,
temperature,
genetic
factors,
stress,
smoking,
and
obesity,
studies
on
these
are
also
increasing.
In
addition,
hydrogels,
electrospun
nanofibers,
foams,
films,
plant-based
materials,
chitosan,
gelatin,
3D
printing,
chemosensors
However,
although
there
many
data
related
healing,
not
that
have
systematically
divided
them
into
structures,
monitoring
through
a
review
literature.
Therefore,
based
various
wound-healing
materials
were
classified
structures
(films,
gauzes,
nanofibers),
chemical
nature-based
sensors,
literature
was
conducted.
