Composite Nanofiber Membrane-Based Microfluidic Fluorescence Sensors for Sweat Analysis DOI
Xuecui Mei, Lei Zhou, Liang Zhu

et al.

Analytical Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 26, 2024

Microfluidic chips play a crucial role in wearable sensors for sweat collection. However, previously reported microfluidic chips, such as those based on poly(dimethylsiloxane) (PDMS) and paper, encounter accumulation at the skin–sensor interface practical applications, which consequently affects both sensing stability wearing comfort. Herein, we propose composite nanofiber membrane (CNMF)-based chip situ The CNMF with directional water transport capability was integrated patterned PDMS to prepare chips. On one hand, can be automatically transported analysis area along designed pathway. other transfers from hydrophobic close skin hydrophilic membrane, effectively avoiding facilitating comfortable microenvironment. Subsequently, constructed CNMF-based fluorescence sensor of multiple targets human sweat. A portable 3D-printed device employed visual signal output. Results indicated that exhibits excellent reliability collecting analyzing This work provides new insights into construction enhanced

Language: Английский

Recent Advancements in Fused Deposition Modeling DOI Open Access

Umer Raza,

Arslan Ahmed, Saad Waheed

et al.

Polymers for Advanced Technologies, Journal Year: 2025, Volume and Issue: 36(1)

Published: Jan. 1, 2025

ABSTRACT Additive manufacturing (AM) is a continuously growing field composed of numerous part‐building approaches that involve the creation products in layer‐by‐layer fashion. Fused deposition modeling (FDM) three‐dimensional printing or AM technique being adopted on an industrial scale and utilized to make parts for commercial use mainly medical sector these days. It has become need hour study parameters FDM understand print behavior optimize process with better mechanical properties. This review paper provides understanding development optimization various materials like Nylon, polylactic acid (PLA), acrylonitrile butadiene styrene (ABS), polyether ether ketone (PEEK) by utilizing different designs techniques Taguchi response surface methodology. Regarding relevant properties, influence layer thickness, raster angle, build orientations, width, infill density are underlined carefully. The also concludes optimized obtain best properties such as tensile flexural strength PLA, PEEK, ABS. literature up‐to‐date references highlights future recommendations fabricated components.

Language: Английский

Citations

2

Advances in Wearable Biosensors for Healthcare: Current Trends, Applications, and Future Perspectives DOI Creative Commons
Dang-Khoa Vo, Kieu The Loan Trinh

Biosensors, Journal Year: 2024, Volume and Issue: 14(11), P. 560 - 560

Published: Nov. 18, 2024

Wearable biosensors are a fast-evolving topic at the intersection of healthcare, technology, and personalized medicine. These sensors, which frequently integrated into clothes accessories or directly applied to skin, provide continuous, real-time monitoring physiological biochemical parameters such as heart rate, glucose levels, hydration status. Recent breakthroughs in downsizing, materials science, wireless communication have greatly improved functionality, comfort, accessibility wearable biosensors. This review examines present status biosensor with an emphasis on advances sensor design, fabrication techniques, data analysis algorithms. We analyze diverse applications clinical diagnostics, chronic illness management, fitness tracking, emphasizing their capacity transform health facilitate early disease diagnosis. Additionally, this seeks shed light future healthcare wellness by summarizing existing trends new advancements.

Language: Английский

Citations

16

Cortisol: Biosensing and detection strategies DOI

Sesuraj Balasamy,

Raji Atchudan, Sandeep Arya

et al.

Clinica Chimica Acta, Journal Year: 2024, Volume and Issue: 562, P. 119888 - 119888

Published: July 24, 2024

Language: Английский

Citations

10

Recent Studies on Smart Textile-Based Wearable Sweat Sensors for Medical Monitoring: A Systematic Review DOI Creative Commons

Asma Akter,

Md Mehedi Hasan Apu, Yedukondala Rao Veeranki

et al.

Journal of Sensor and Actuator Networks, Journal Year: 2024, Volume and Issue: 13(4), P. 40 - 40

Published: July 11, 2024

Smart textile-based wearable sweat sensors have recently received a lot of attention due to their potential for use in personal medical monitoring. They variety desirable qualities, including low cost, easy implementation, stretchability, flexibility, and light weight. Wearable are approach personalized devices because these features. Moreover, real-time can easily monitor health by analyzing the produced human body. We reviewed most recent advancements from fabrication, materials, disease detection monitoring perspectives. To integrate biosensors with electronics introduce field technology, key chemical constituents sweat, collection technologies, concerns textile substrates elaborated. Perspectives building biosensing systems based on reviewed, as well methods difficulties involved enhancing sweat-sensing performance.

Language: Английский

Citations

8

Development and application of novel biosensors for enhanced detection in medical diagnostics DOI
A.M. Elbasiony, Sarah Alharthi, Mohamed Mohamady Ghobashy

et al.

Microchemical Journal, Journal Year: 2024, Volume and Issue: unknown, P. 111938 - 111938

Published: Oct. 1, 2024

Language: Английский

Citations

6

A physiological perspective of the relevance of sweat biomarkers and their detection by wearable microfluidic technology: A review DOI Creative Commons

Sergi Cinca-Morros,

Sandra García-Rey,

Jesús Álvarez‐Herms

et al.

Analytica Chimica Acta, Journal Year: 2024, Volume and Issue: 1327, P. 342988 - 342988

Published: July 19, 2024

The great majority of published microfluidic wearable platforms for sweat sensing focus on the development technology to fabricate device, integration materials and actuators fluidics within device. However, very few papers have discussed physiological relevance metabolites measured using these novel approaches. In fact, some analytes present in sweat, which serve as biomarkers blood, do not show a correlation with blood levels. This discrepancy can be attributed factors such contamination during measurements, metabolism glands, or challenges obtaining significant samples. objective this review is critical meaningful insight into real applicability potential use improving health sport performance. It also discusses current limitations future microfluidics, aiming provide accurate information about actual needs field. work expected contribute more suitable sports science monitoring, biofluid analysis.

Language: Английский

Citations

5

Biocompatible materials for next-generation biosensors DOI Creative Commons
Gideon Okibe, Humphrey Sam Samuel,

Isah Adeiza Okino

et al.

Discover Chemistry., Journal Year: 2024, Volume and Issue: 1(1)

Published: Oct. 25, 2024

Biosensor is a revolutionary diagnostic tool that harnesses the synergy of biology and technology to detect quantify target analytes, enabling real-time monitoring, early disease diagnosis, innovative applications. Recent advancements in biocompatible materials have brought about significant transformation development biosensors. These tools are essential modern healthcare diagnostics environmental monitoring. This article highlights crucial role enhancing performance safety next-generation Innovative substances such as graphene, hydrogels, nanocomposites been developed, significantly improving sensor functionality compatibility with biological systems. However, challenges associated deploying these include scalability, manufacturing processes, long-term stability. emphasizes transformative potential advancing biosensor technologies expanding their applications across various fields. Detailed analysis illustrates how contribute evolution biosensors, offering more precise, reliable, accessible diagnostics.

Language: Английский

Citations

4

Recent Advancements in Microfluidic Biosensors for Clinical Applications DOI Creative Commons
Haiyan Wang, Wenjuan Wu

iLABMED, Journal Year: 2025, Volume and Issue: unknown

Published: March 10, 2025

ABSTRACT The combination of low‐consumption microfluidic chips and high‐sensitivity biosensors enables rapid accurate detection complex target analytes. This integrated system holds significant potential for applications in disease diagnosis, health monitoring, treatment management. Advances novel biomaterials have led to device integration into wearable implantable systems point‐of‐care testing. Here, we review recent advances clinical detecting nucleic acids, proteins, metabolites, pathogens, cellular components. We outline the prospects devices based on analysis biofluids such as sweat discuss remaining challenges facing application biosensors.

Language: Английский

Citations

0

New Frontiers for the Early Diagnosis of Cancer: Screening miRNAs Through the Lateral Flow Assay Method DOI Creative Commons

Afsaneh Emamiamin,

Seyedeh Rojin Shariati Pour, Thea Serra

et al.

Biosensors, Journal Year: 2025, Volume and Issue: 15(4), P. 238 - 238

Published: April 8, 2025

MicroRNAs (miRNAs), which circulate in the serum and plasma, play a role several biological processes, their levels body fluids are associated with pathogenesis of various diseases, including different types cancer. For this reason, miRNAs considered promising candidates as biomarkers for diagnostic purposes, enabling early detection pathological onset monitoring drug responses during therapy. However, current methods miRNA quantification, such northern blotting, isothermal amplification, RT-PCR, microarrays, next-generation sequencing, limited by reliance on centralized laboratories, high costs, need specialized personnel. Consequently, development sensitive, simple, one-step analytical techniques is highly desirable, particularly given importance diagnosis prompt treatment cases Lateral flow assays (LFAs) among most attractive point-of-care (POC) devices healthcare applications. These systems allow rapid straightforward analytes using low-cost setups that accessible to wide audience. This review focuses LFA-based detecting quantifying cancers, particular emphasis sensitivity enhancements achieved through application labels systems. Early, non-invasive these diseases quantification tailored can significantly reduce mortality, improve survival rates, lower costs.

Language: Английский

Citations

0

Advancements in Wearable and Implantable BioMEMS Devices: Transforming Healthcare Through Technology DOI Creative Commons
Vishnuram Abhinav,

Prithvi Basu,

Saurabh Verma

et al.

Micromachines, Journal Year: 2025, Volume and Issue: 16(5), P. 522 - 522

Published: April 28, 2025

Wearable and implantable BioMEMSs (biomedical microelectromechanical systems) have transformed modern healthcare by enabling continuous, personalized, minimally invasive monitoring, diagnostics, therapy. advanced rapidly, encompassing a diverse range of biosensors, bioelectronic systems, drug delivery platforms, motion tracking technologies. These devices enable non-invasive, real-time monitoring biochemical, electrophysiological, biomechanical signals, offering personalized proactive solutions. In parallel, BioMEMS significantly enhanced long-term targeted delivery, neurostimulation. From continuous glucose intraocular pressure to programmable bioelectric implants for neuromodulation, these are improving precision treatment localized This review explores the materials technologies driving advancements in wearable BioMEMSs, focusing on their impact chronic disease management, cardiology, respiratory care, glaucoma treatment. We also highlight integration with artificial intelligence (AI) Internet Things (IoT), paving way smarter, data-driven Despite potential, face challenges such as regulatory complexities, global standardization, societal determinants. Looking ahead, we explore emerging directions like multifunctional biodegradable power sources, next-generation point-of-care diagnostics. Collectively, position pivotal enablers future patient-centric systems.

Language: Английский

Citations

0