Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 26, 2024
Microfluidic
chips
play
a
crucial
role
in
wearable
sensors
for
sweat
collection.
However,
previously
reported
microfluidic
chips,
such
as
those
based
on
poly(dimethylsiloxane)
(PDMS)
and
paper,
encounter
accumulation
at
the
skin–sensor
interface
practical
applications,
which
consequently
affects
both
sensing
stability
wearing
comfort.
Herein,
we
propose
composite
nanofiber
membrane
(CNMF)-based
chip
situ
The
CNMF
with
directional
water
transport
capability
was
integrated
patterned
PDMS
to
prepare
chips.
On
one
hand,
can
be
automatically
transported
analysis
area
along
designed
pathway.
other
transfers
from
hydrophobic
close
skin
hydrophilic
membrane,
effectively
avoiding
facilitating
comfortable
microenvironment.
Subsequently,
constructed
CNMF-based
fluorescence
sensor
of
multiple
targets
human
sweat.
A
portable
3D-printed
device
employed
visual
signal
output.
Results
indicated
that
exhibits
excellent
reliability
collecting
analyzing
This
work
provides
new
insights
into
construction
enhanced
Sensors & Diagnostics,
Journal Year:
2024,
Volume and Issue:
3(8), P. 1234 - 1246
Published: Jan. 1, 2024
While
point-of-care
(POC)
biosensors
have
enormous
potential
to
help
guide
and
inform
clinical
decisions
at
a
patient's
location,
the
translation
of
fundamental,
applied,
proof-of-concept
into
commercial
products
is
complex.
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(12), P. 6393 - 6393
Published: June 10, 2024
Rich
biological
information
in
sweat
provides
great
potential
for
health
monitoring
and
management.
However,
due
to
the
complexity
of
sweat,
development
environmentally
friendly
green
electronic
products
is
significance
construction
ecological
civilization.
This
study
utilized
a
simple
combination
polystyrene
sulfonate
sodium
(PSS)
filter
paper
(FP)
prepare
cellulose
materials
coated
with
conductive
polymers,
developing
an
electrochemical
sensor
based
on
modified
materials.
The
mechanical
properties
fabricated
PSS/FP
membrane
were
optimized
by
adjusting
feeding
dosage
PSS.
realized
composite
containing
7%
PSS
displayed
good
conductivity
(9.1
×
10−2
S/m),
reducing
electric
resistance
99.2%
compared
original
FP
(6.7
10−4
S/m).
stable
current
simulated
under
different
pH
environments
highly
correlated
values.
Additionally,
when
exposed
varying
ion
concentrations,
signal
changes
real
time
concentration
variations.
response
averages
around
0.3
s.
Biosensors,
Journal Year:
2024,
Volume and Issue:
14(12), P. 584 - 584
Published: Nov. 30, 2024
Hypoxia,
characterized
by
inadequate
tissue
oxygenation,
may
result
in
damage
and
organ
failure
if
not
addressed.
Current
detection
approaches
frequently
prove
insufficient,
depending
on
symptoms
rudimentary
metrics
such
as
which
fail
to
comprehensively
identify
the
onset
of
hypoxia.
The
European
Pressure
Ulcer
Advisory
Panel
(EPUAP)
has
recognized
sweat
lactate
a
possible
marker
for
early
identification
decubitus
ulcers,
nevertheless,
neither
nor
oxygenation
independently
provides
an
appropriate
diagnosis
We
have
fabricated
wearable
device
that
non-invasively
concurrently
monitors
fill
this
gap.
apparatus
comprises
three
essential
components:
(i)
hydrogel-based
colorimetric
biosensor,
(ii)
near-infrared
(NIR)
sensor
assessing
(iii)
integrated
form
factor
enhanced
wearability.
alters
its
hue
upon
interaction
with
sweat,
whereas
NIR
levels
real-time.
underwent
testing
phantom
exhibiting
tissue-mimicking
characteristics
human
post
aerobic
anaerobic
activities.
Moreover,
was
demonstrated
be
capable
real-time
“on-body”
simultaneous
monitoring
spikes
(StO2)
drops,
showed
strong
correlation
during
hypoxia
protocol.
This
innovative
technology
wide
range
potential
applications,
post-operative
care,
sepsis
detection,
athletic
performance
monitoring,
provide
economical
healthcare
solutions
resource-limited
regions.
Royal Society of Chemistry eBooks,
Journal Year:
2024,
Volume and Issue:
unknown, P. 95 - 120
Published: Dec. 20, 2024
Fluorometric
sensors
and
devices
are
important
tools
for
the
detection
measurement
of
biomarkers,
which
indicators
biological
processes
diseases.
These
involve
emission
light
from
fluorescent
molecules
upon
interaction
with
target
biomolecules,
resulting
in
a
measurable
signal.
Fluorescence-based
techniques,
instance,
fluorescence
microscopy,
fluorometry,
resonance
energy
transfer
(FRET),
probes,
enable
researchers
to
study
high
sensitivity
specificity.
offer
numerous
benefits
over
conventional
methods,
like
higher
sensitivity,
selectivity,
versatility,
ability
sense
various
biomarkers
instantaneously.
In
this
chapter,
we
provide
an
overview
recent
developments
fluorometric
biomarker
detection,
including
design
principles,
sensing
mechanisms,
fabrication
techniques
developing
sensors.
The
challenges
future
directions
technology
also
discussed.
This
chapter
highlights
importance
these
advancing
our
understanding
systems
their
potential
improving
healthcare,
food
safety,
environmental
monitoring.
