Dietary Tannic Acid Promotes Growth Performance and Resistance Against Aeromonas hydrophila Infection by Improving the Antioxidative Capacity and Intestinal Health in the Chinese Soft-Shelled Turtle (Pelodiscus sinensis) DOI Creative Commons
Liqin Ji,

Yisen Shangguan,

Chen Chen

et al.

Antioxidants, Journal Year: 2025, Volume and Issue: 14(1), P. 112 - 112

Published: Jan. 20, 2025

To investigate the effect of tannic acid (TA) on growth, disease resistance, and intestinal health Chinese soft-shelled turtles, individual turtles were fed with 0 g/kg (CG), 0.5 g/kg, 1 2 4 TA diets for 98 days. Afterwards, turtles’ resistance was tested using Aeromonas hydrophila. The results showed that 0.5–4 dietary increased growth performance feed utilization (p < 0.05), 2.38 being optimal level specific rate (SGR). addition in mucosal fold height submucosa thickness small intestine, which reached a maximum g/kg. 0.5–2 effectively reduced cumulative mortality had been induced by A. hydrophila, dosage leading to lowest mortality. Additionally, 1–4 improved T-SOD, CAT, GSH-Px activities during infection, while enhanced richness diversity microbiota, example, increasing Actinobacteria but inhibiting Firmicutes. transcriptome demonstrated predominant differentially expressed genes (DEGs) TA2 mainly enriched PPAR signaling pathway (Acsl5, Apoa2, Apoa5, Fabp1, Fabp2, Fabp6); glycine, serine, threonine metabolism (Chdh, Gatm, Shmt1); steroid biosynthesis (Cel, Hsd17b7, Soat2, Sqle). main metabolites (DEMs) discovered means metabolome analysis included cholylhistidine, calcipotriol, 13-O-tetradecanoylphorbol 12-acetate, hexahomomethionine CG vs. TA2. Integrative analyses two omics revealed mitigated inflammation activating regulating lipid via multiple pathways, such as α-linolenic metabolism. In general, inclusion turtle can optimally promote bacterial maintaining improving antioxidant capacity.

Language: Английский

Dietary Tannic Acid Promotes Growth Performance and Resistance Against Aeromonas hydrophila Infection by Improving the Antioxidative Capacity and Intestinal Health in the Chinese Soft-Shelled Turtle (Pelodiscus sinensis) DOI Creative Commons
Liqin Ji,

Yisen Shangguan,

Chen Chen

et al.

Antioxidants, Journal Year: 2025, Volume and Issue: 14(1), P. 112 - 112

Published: Jan. 20, 2025

To investigate the effect of tannic acid (TA) on growth, disease resistance, and intestinal health Chinese soft-shelled turtles, individual turtles were fed with 0 g/kg (CG), 0.5 g/kg, 1 2 4 TA diets for 98 days. Afterwards, turtles’ resistance was tested using Aeromonas hydrophila. The results showed that 0.5–4 dietary increased growth performance feed utilization (p < 0.05), 2.38 being optimal level specific rate (SGR). addition in mucosal fold height submucosa thickness small intestine, which reached a maximum g/kg. 0.5–2 effectively reduced cumulative mortality had been induced by A. hydrophila, dosage leading to lowest mortality. Additionally, 1–4 improved T-SOD, CAT, GSH-Px activities during infection, while enhanced richness diversity microbiota, example, increasing Actinobacteria but inhibiting Firmicutes. transcriptome demonstrated predominant differentially expressed genes (DEGs) TA2 mainly enriched PPAR signaling pathway (Acsl5, Apoa2, Apoa5, Fabp1, Fabp2, Fabp6); glycine, serine, threonine metabolism (Chdh, Gatm, Shmt1); steroid biosynthesis (Cel, Hsd17b7, Soat2, Sqle). main metabolites (DEMs) discovered means metabolome analysis included cholylhistidine, calcipotriol, 13-O-tetradecanoylphorbol 12-acetate, hexahomomethionine CG vs. TA2. Integrative analyses two omics revealed mitigated inflammation activating regulating lipid via multiple pathways, such as α-linolenic metabolism. In general, inclusion turtle can optimally promote bacterial maintaining improving antioxidant capacity.

Language: Английский

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