Symptoms and conventional treatments of Alzheimer's disease DOI
Mehul R. Chorawala, Aayushi C. Shah,

Aanshi J. Pandya

et al.

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 213 - 234

Published: Jan. 1, 2024

Language: Английский

Development of asparagine endopeptidase inhibitors for treating neurodegenerative diseases DOI

Xin Meng,

Bowei Li, Mengmeng Wang

et al.

Trends in Molecular Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

1
Targeting of neuroinflammation by glibenclamide in Covid-19: old weapon from arsenal DOI Creative Commons
Gaber El‐Saber Batiha, Hayder M. Al‐kuraishy, Ali I. Al‐Gareeb

et al.

Inflammopharmacology, Journal Year: 2022, Volume and Issue: 31(1), P. 1 - 7

Published: Nov. 23, 2022

Abstract In coronavirus disease 2019 (Covid-19) era, neuroinflammation may develop due to neuronal tropism of severe acute respiratory syndrome type 2 (SARS-CoV-2) and/or associated immune activation, cytokine storm, and psychological stress. SARS-CoV-2 infection linked storm cause blood–brain barrier (BBB) injury through which activated cells can pass into the brain causing activation glial with subsequent neuroinflammation. Different therapeutic regimens were suggested alleviate Covid-19-induced Since glibenclamide has anti-inflammatory neuroprotective effects, it could be effective in mitigation infection-induced Glibenclamide is a second-generation drug from sulfonylurea family, acts by inhibiting adenosine triphosphate (ATP)-sensitive K channel regulatory subunit 1 receptor (SUR-1) pancreatic β cells. reduces BBB nod-like pyrin 3 (NLRP3) inflammasome, oxidative stress, microglial activation. Therefore, inhibition NLRP3 stress attenuate SARS-CoV-2-mediated

Language: Английский

Citations

37
Benzodiazepines in Alzheimer’s disease: beneficial or detrimental effects DOI
Hayder M. Al‐kuraishy, Ali I. Al‐Gareeb, ‏Hebatallah M. Saad

et al.

Inflammopharmacology, Journal Year: 2022, Volume and Issue: 31(1), P. 221 - 230

Published: Nov. 23, 2022

Language: Английский

Citations

33
The conceivable role of prolactin hormone in Parkinson disease: The same goal but with different ways DOI

Haydar M. Al‐kuraishy,

Majid S. Jabir, Ali I. Al‐Gareeb

et al.

Ageing Research Reviews, Journal Year: 2023, Volume and Issue: 91, P. 102075 - 102075

Published: Sept. 14, 2023

Language: Английский

Citations

23
Symptoms and conventional treatments of Alzheimer's disease DOI
Mehul R. Chorawala, Aayushi C. Shah,

Aanshi J. Pandya

et al.

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 213 - 234

Published: Jan. 1, 2024

Language: Английский

Citations

8