Enhancing chronic low back pain management: an initial neuroimaging study of a mobile interoceptive attention training DOI Creative Commons
Irina A. Strigo,

Sergio Garcia Guerra,

Salvatore Torrisi

et al.

Frontiers in Pain Research, Journal Year: 2024, Volume and Issue: 5

Published: Sept. 30, 2024

Introduction Chronic low back pain (cLBP) poses significant challenges, often addressed through avoidance or distraction. Emerging evidence suggests that mind-body interventions, like our novel Mind Your Pain (MyP) smartphone mobile application, may offer relief. We conducted a single-arm, mixed-methods neuroimaging study to assess the degree which treatment response 8-week intervention, as measured by reduction in Pain, Enjoyment of Life and General Activity Scale (PEG), was associated with enhanced pain-related insula activation over time. Methods Twenty-nine individuals cLBP completed patient-reported assessments, qualitative sensory testing (QST) measures, pre- post-MyP. Functional MRI data during experimental heat on left forearm were collected analyzed, comparing responders (≥50% PEG scores) non-responders. Results MyP led decreases scores overall. Furthermore, exhibited increased key brain regions, including contralateral posterior insula, bilateral ventral anterior cingulate, dorsolateral prefrontal cortex, nucleus accumbens. Although baseline behavioral measures did not differ between two responder groups, neural differences related impact endogenous observed. Discussion appears modify underlying circuitry, suggesting changes interoception serve biomarkers for interventions cLBP. This highlights potential approach management, warranting further investigation.

Language: Английский

Patient Outcomes Improve in a Pragmatic Implementation Pilot Study of Mindful Awareness in Body-Oriented Therapy (MABT) for Chronic Pain DOI
Cynthia Price, Dana Dharmakaya Colgan, Erin Abu-Rish Blakeney

et al.

Global Advances in Integrative Medicine and Health, Journal Year: 2025, Volume and Issue: 14

Published: March 1, 2025

Objectives Non-pharmacologic approaches are now considered best practice for the treatment of chronic pain. The purpose this pilot study was to evaluate patient responses a newly integrated clinic service called Mindful Awareness in Body-oriented Therapy (MABT) at pain clinic. MABT is designed develop interoceptive sensibility improved well-being and emotion regulation. Methods A one-group repeated measures design used examine referral delivery follow-through feasibility change on health outcomes among patients. Upon referral, participants were scheduled program involving eight individual sessions with one massage therapists trained MABT. Measures administered baseline, post-intervention (3 months) 6 month follow-up). Outcome assessed physical mental distress, awareness, emotional well-being. Analyses included descriptive statistics ANOVA. Results Seventy patients referred 41 received least session. Thirty (73%) completed intervention. Statistically and/or clinically significant improvements identified most subscales PROMIS-29 (the primary outcome), including Physical Function, Fatigue, Anxiety, Sleep Disturbance, Social Roles, Pain Interference. Improvements regulation difficulties also demonstrated statistically large effects. Discussion This demonstrates when delivered real-life context. Significant effects response intervention offers promising non-pharmacological approach

Language: Английский

Citations

0

Limbic-Sensorimotor Tug of War for the Hippocampus: Dynamic Functional Connectivity as a Transdiagnostic Vulnerability Marker in Offspring of Emotion Dysregulation Patients DOI Creative Commons
Luigi F. Saccaro, Farnaz Delavari, Ben Meuleman

et al.

Biological Psychiatry Cognitive Neuroscience and Neuroimaging, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

0

Mindful moms: acceptability and impact of co-designed and digitally delivered video meditations for pregnant and parenting women with opioid use disorder DOI Creative Commons
Sarah Lord, Deepika Rao

Annals of Medicine, Journal Year: 2025, Volume and Issue: 57(1)

Published: April 18, 2025

Perinatal opioid use disorder (OUD) remains a public health epidemic. Stress, anxiety and depression are disproportionately high among this population associated with poor recovery outcomes. Mindfulness interventions show promise for supporting women. This paper reports results of pilot study to evaluate initial efficacy acceptability digitally delivered mindfulness meditation videos reduce stress promote women in recovery. Women lived experience OUD were recruited from three outpatient programs that provided care pregnant parenting history rural northern New England (2 maternity settings offered buprenorphine as part their service menu 1 academic substance treatment setting). In pre-post design, participants randomly assigned receive four 16 short videos, each by email survey link over 2-week period per week) Videos co-designed earlier work representative end-users, guided evidence-based interventions. Assessment included the Perceived Stress Scale Attention Awareness Scale. Participants rated video on usefulness, enjoyability, ability lower anxiety, intention future. also open-ended feedback about videos. Data analyzed using descriptive statistics, paired t-tests, generalized linear modeling. A total 20 women, ages 24-36 years, completed study. Most (95%) white non-Hispanic, reflecting region. Marginal mean perceived scores decreased significantly 21.49 19.85 [p = 0.05, d 0.43] increased 3.47 3.76 0.04, 0.45]. Overall, highly acceptable useful majority (80%) indicated meditations Digitally low dose intervention reduced improved mindfulness. Findings inform directions future research larger samples effectiveness accessible digital support strategies broadly implementing intervention.

Language: Английский

Citations

0

Interoceptive posture awareness and accuracy: a novel photographic strategy towards making posture actionable DOI Creative Commons

Steven P. Weiniger,

Nathan D. Schilaty

Frontiers in Neuroscience, Journal Year: 2024, Volume and Issue: 18

Published: April 4, 2024

Interoception, sometimes referred to as the ‘hidden sense,’ communicates state of internal conditions for autonomic energy regulation and is important human motor control well self-awareness. The insula, cortex interoception, integrates senses such hunger, thirst emotions. With input from cerebellum proprioceptive inputs, it creates a vast sensorimotor network essential static posture dynamic movement. humans being bipedal allow improved mobility utilization, greater neuromotor required effectively stabilize four postural zones mass (i.e., head, torso, pelvis, lower extremities) over base support. In state, this that maintains verticality critical, challenging management somatic visceral functions. perspective article, authors promote simple series photographs one integrate more accurate alignment their with respect gravity line by correlating cortical interoception cognitive feedback. Doing focuses on body perception in space compared objective images. Strengthening interoceptive awareness can shift net result each zone during day-to-day movement towards stronger biomechanics serve an individualized strategy optimize function, longevity, rehabilitation.

Language: Английский

Citations

2

EFFECTS OF MINDFULNESS-BASED INTERVENTIONS ON SYMPTOMS AND INTEROCEPTION IN TRAUMA-RELATED DISORDERS AND EXPOSURE TO TRAUMATIC EVENTS: SYSTEMATIC REVIEW AND META-ANALYSIS DOI Creative Commons
Laura Molteni, Corentin J. Gosling, Harry Fagan

et al.

Psychiatry Research, Journal Year: 2024, Volume and Issue: 336, P. 115897 - 115897

Published: April 6, 2024

Interoception is defined as the sense of internal state body. Dysfunctions in interoception are found several mental disorders, including trauma-related conditions. Mindfulness-Based Interventions (MBIs) have been shown to influence interoceptive processes. Randomised controlled trials (RCTs) investigated whether MBIs impact symptoms and patients with disorders. We undertook a systematic review meta-analysis synthesize these data. included RCTs an MBI arm which enrolled adult trauma related-disorders or exposure traumatic experience, addressed changes symptoms. A random-effects multivariate meta-analytic model was performed quantify group differences score change from baseline follow-up. Twelve studies were review, eleven meta-analysis. Overall, showed small moderate positive effects on both Despite high heterogeneity results, sensitivity analyses confirmed robustness findings. conclude that efficacy supported by randomised evidence. However, further research needed understand might underpin effectiveness

Language: Английский

Citations

2

Modulation of posterior default mode network activity during interoceptive attention and relation to mindfulness DOI Creative Commons
Dhakshin Ramanathan, Jason Nan, Gillian Grennan

et al.

Biological Psychiatry Global Open Science, Journal Year: 2024, Volume and Issue: 4(6), P. 100384 - 100384

Published: Aug. 24, 2024

Interoceptive attention to internal sensory signals, such as the breath, is fundamental mindfulness. However, interoceptive can be difficult study with many studies relying on subjective and retrospective measures. Response consistency an established method for evaluating variability of exteroceptive tasks but has rarely been applied task. In this study, we measured response times a breath-monitoring task in individuals across lifespan (15-91 years age, n=324) simultaneous electroencephalography (EEG). We found that breath monitoring was positively correlated attentive performance inhibitory control EEG source reconstruction showed on-task alpha band (8-12 Hz) activity greater than at rest. Low consistency/longer responses were associated elevated brain relative high particularly posterior default mode network (pDMN) regions. pDMN inversely linked functional connectivity fronto-parietal (FPN) cinguloopercular (CON) not rest, suggesting role these frontal networks regulation activity. its precuneus region subjects reporting low mindfulness, adaptively modulated by difficulty independent experiment. Elevated serves objective neural marker responding during attention, scales

Language: Английский

Citations

2

Immediate Effects of Mindful Awareness in Body-Oriented Therapy as an Adjunct to Medication for Opioid Use Disorder DOI Creative Commons
Cynthia Price, Kenneth C. Pike,

Anna Treadway

et al.

Mindfulness, Journal Year: 2024, Volume and Issue: 15(11), P. 2794 - 2811

Published: Nov. 1, 2024

The need for improve medication opioid use disorder (MOUD) treatment outcomes can be limited by co-occurring polysubstance use, mental health, and chronic pain conditions. Interoceptive training may facilitate well-being support MOUD. While effective, This study examined the pre-post effects of mindfulness-based intervention Mindful Awareness in Body-oriented Therapy (MABT) as an adjunct to MABT teaches interoceptive awareness skills promote self-care emotion regulation. Participants stabilized on (OUD) (n = 303) from six community clinics Northwestern United States were recruited randomly assigned plus MOUD or only. In a mixed-methods study, we used intent-to-treat approach (analyzing participants based their group, regardless adherence) examine proportion days abstinent non-prescribed opioids, other substance (primary outcomes) at baseline 3 months post-intervention. Secondary included symptoms health distress, emotional regulation difficulties, physical symptom indicators, awareness, mindfulness skills. Participant experience was collected through post-intervention surveys. Changes assessed using linear mixed models; content analysis analyze qualitative data. Levels overall low did not differ between groups. Significant improvements PTSD symptoms, severity, activity interference, frequency found those who received compared this stable population, improved; however, demonstrated significant positive changes across multiple critical improving treatment. ClinicalTrials.gov identifer: NCT04082637.

Language: Английский

Citations

2

Immediate Effects of Mindful Awareness in Body-oriented Therapy as an Adjunct to Medication for Opioid Use Disorder DOI

Cynthia Price,

Kenneth C. Pike,

Anna Treadway

et al.

Published: July 15, 2024

While effective, medication for opioid use disorder (MOUD) treatment outcomes can be limited by co-occurring polysubstance use, mental health and chronic pain conditions. Interoceptive training may facilitate well-being support MOUD. This study examined the pre-post effects of mindfulness-based intervention Mindful Awareness in Body-oriented Therapy (MABT) as an adjunct to MABT teaches interoceptive awareness skills promote self-care emotion regulation.

Language: Английский

Citations

0

Enhancing chronic low back pain management: an initial neuroimaging study of a mobile interoceptive attention training DOI Creative Commons
Irina A. Strigo,

Sergio Garcia Guerra,

Salvatore Torrisi

et al.

Frontiers in Pain Research, Journal Year: 2024, Volume and Issue: 5

Published: Sept. 30, 2024

Introduction Chronic low back pain (cLBP) poses significant challenges, often addressed through avoidance or distraction. Emerging evidence suggests that mind-body interventions, like our novel Mind Your Pain (MyP) smartphone mobile application, may offer relief. We conducted a single-arm, mixed-methods neuroimaging study to assess the degree which treatment response 8-week intervention, as measured by reduction in Pain, Enjoyment of Life and General Activity Scale (PEG), was associated with enhanced pain-related insula activation over time. Methods Twenty-nine individuals cLBP completed patient-reported assessments, qualitative sensory testing (QST) measures, pre- post-MyP. Functional MRI data during experimental heat on left forearm were collected analyzed, comparing responders (≥50% PEG scores) non-responders. Results MyP led decreases scores overall. Furthermore, exhibited increased key brain regions, including contralateral posterior insula, bilateral ventral anterior cingulate, dorsolateral prefrontal cortex, nucleus accumbens. Although baseline behavioral measures did not differ between two responder groups, neural differences related impact endogenous observed. Discussion appears modify underlying circuitry, suggesting changes interoception serve biomarkers for interventions cLBP. This highlights potential approach management, warranting further investigation.

Language: Английский

Citations

0