Advances in magnetic field approaches for non-invasive targeting neuromodulation DOI Creative Commons
Mozhgan Alipour,

Maryam Abdolmaleki,

Yaser Shabanpour

et al.

Frontiers in Human Neuroscience, Journal Year: 2025, Volume and Issue: 19

Published: April 28, 2025

Neuromodulation, the targeted regulation of nerve activity, has emerged as a promising approach for treating various neurological and psychiatric disorders. While deep brain stimulation shown efficacy, its invasive nature poses substantial risks, including surgical complications high costs. In contrast, non-invasive neuromodulation techniques, particularly those utilizing magnetic fields (MFs), have gained increasing attention safer, more accessible alternatives. Magnetothermal an innovative method that enables precise modulation neuronal ion channels through localized heating induced by interaction MF with biological tissues. This review discusses principles MF-based highlights critical role in synaptic transmission, therapeutic potential these advanced techniques. Additionally, it key challenges such spatial targeting precision, safety considerations, long-term effects exposure on function. The findings presente promise non-invasive, highly strategy conditions epilepsy, movement disorders, neurodegenerative diseases, applications chronic pain management future clinical interventions.

Language: Английский

Artificial intelligence in stroke rehabilitation: From acute care to long-term recovery DOI
Spandana Rajendra Kopalli, Madhu Shukla,

B Jayaprakash

et al.

Neuroscience, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

0
A system generating an impulse magnetic field with a closed magnetic circuit and a thyristor as a switching element DOI
A. Skumiel, R. Wojciechowski

Journal of Magnetism and Magnetic Materials, Journal Year: 2025, Volume and Issue: unknown, P. 173003 - 173003

Published: March 1, 2025

Language: Английский

Citations

0
Therapeutic potential and mechanisms of repetitive transcranial magnetic stimulation in Alzheimer’s disease: a literature review DOI Creative Commons
Xinlei Zhang, Lingling Zhu, Yuan Li

et al.

European journal of medical research, Journal Year: 2025, Volume and Issue: 30(1)

Published: April 4, 2025

Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder, affecting tens of millions worldwide with projections indicating increasing prevalence in coming decades. Characterized by progressive cognitive decline, AD manifests varying degrees executive, language, and visuospatial impairments that worsen over time, eventually leading to severe psychiatric symptoms, mobility difficulties, sleep disturbances, incontinence. While pharmacological treatments remain primary intervention approach, their efficacy often diminishes time may produce significant adverse effects. Repetitive transcranial magnetic stimulation (rTMS), as a non-invasive neuromodulation technique, has emerged promising alternative or complementary therapy. This literature review examines therapeutic potential mechanisms rTMS disease. Through electromagnetic induction, can selectively modulate cortical excitability, high-frequency (≥ 5 Hz) enhancing neural excitability low-frequency (≤ 1 producing inhibitory Recent clinical evidence demonstrates significantly improve function, memory, language abilities, motor performance patients, particularly when administered optimized parameters targeting key brain regions, such dorsolateral prefrontal cortex. The neurobiological underlying these effects include enhanced synaptic plasticity, increased expression neurotrophic factors, modulation neurotransmitter systems, reduction pathological protein aggregation. Meta-analyses indicate protocols (particularly 20 delivered at least 3 weeks minimum sessions improvements, potentially persisting for months post-treatment. Combined approaches integrating training show particular promise through synergistic enhancement neuroplasticity. Despite encouraging results, standardization treatment larger trials are needed establish definitive guidelines determine long-term efficacy. synthesizes current supporting an effective alleviating symptoms while highlighting opportunities advancing its application.

Language: Английский

Citations

0
Advances in magnetic field approaches for non-invasive targeting neuromodulation DOI Creative Commons
Mozhgan Alipour,

Maryam Abdolmaleki,

Yaser Shabanpour

et al.

Frontiers in Human Neuroscience, Journal Year: 2025, Volume and Issue: 19

Published: April 28, 2025

Neuromodulation, the targeted regulation of nerve activity, has emerged as a promising approach for treating various neurological and psychiatric disorders. While deep brain stimulation shown efficacy, its invasive nature poses substantial risks, including surgical complications high costs. In contrast, non-invasive neuromodulation techniques, particularly those utilizing magnetic fields (MFs), have gained increasing attention safer, more accessible alternatives. Magnetothermal an innovative method that enables precise modulation neuronal ion channels through localized heating induced by interaction MF with biological tissues. This review discusses principles MF-based highlights critical role in synaptic transmission, therapeutic potential these advanced techniques. Additionally, it key challenges such spatial targeting precision, safety considerations, long-term effects exposure on function. The findings presente promise non-invasive, highly strategy conditions epilepsy, movement disorders, neurodegenerative diseases, applications chronic pain management future clinical interventions.

Language: Английский

Citations

0