Brain Markers of Resilience to Psychosis in High-Risk Individuals: A Systematic Review and Label-Based Meta-Analysis of Multimodal MRI Studies
Brain Sciences,
Journal Year:
2025,
Volume and Issue:
15(3), P. 314 - 314
Published: March 17, 2025
Background/Objectives:
Most
individuals
who
have
a
familial
or
clinical
risk
of
developing
psychosis
remain
free
from
psychopathology.
Identifying
neural
markers
resilience
in
these
at-risk
may
help
clarify
underlying
mechanisms
and
yield
novel
targets
for
early
intervention.
However,
contrast
to
studies
on
biomarkers,
are
scarce.
The
current
study
aimed
identify
potential
brain
psychosis.
Methods:
A
systematic
review
the
literature
yielded
total
43
MRI
that
reported
resilience-associated
changes
with
an
elevated
Label-based
meta-analysis
was
used
synthesize
findings
across
modalities.
Results:
Resilience-associated
were
significantly
overreported
default
mode
language
network,
among
highly
connected
central
regions.
Conclusions:
These
suggest
DMN
language-associated
areas
hubs
be
hotspots
changes.
systems
thus
key
interest
as
inquiry
and,
possibly,
intervention
populations.
Language: Английский
Precision Psychiatry for Obsessive-Compulsive Disorder: Clinical Applications of Deep Learning Architectures
Journal of Clinical Medicine,
Journal Year:
2025,
Volume and Issue:
14(7), P. 2442 - 2442
Published: April 3, 2025
Obsessive-compulsive
disorder
(OCD)
is
a
complex
psychiatric
condition
characterized
by
significant
heterogeneity
in
symptomatology
and
treatment
response.
Advances
neuroimaging,
EEG,
other
multimodal
datasets
have
created
opportunities
to
identify
biomarkers
predict
outcomes,
yet
traditional
statistical
methods
often
fall
short
analyzing
such
high-dimensional
data.
Deep
learning
(DL)
offers
powerful
tools
for
addressing
these
challenges
leveraging
architectures
capable
of
classification,
prediction,
data
generation.
This
brief
review
provides
an
overview
five
key
DL
architectures-feedforward
neural
networks,
convolutional
recurrent
generative
adversarial
transformers-and
their
applications
OCD
research
clinical
practice.
We
highlight
how
models
been
used
the
predictors
response,
diagnose
classify
OCD,
advance
precision
psychiatry.
conclude
discussing
implementation
DL,
summarizing
its
advances
promises
underscoring
field.
Language: Английский
The Role of Artificial Intelligence in Managing Bipolar Disorder: A New Frontier in Patient Care
Jelena Milić,
No information about this author
Iva Zrnic,
No information about this author
Edita Grego
No information about this author
et al.
Journal of Clinical Medicine,
Journal Year:
2025,
Volume and Issue:
14(7), P. 2515 - 2515
Published: April 7, 2025
Background/Objectives:
Bipolar
disorder
(BD)
is
a
complex
and
chronic
mental
health
condition
that
poses
significant
challenges
for
both
patients
healthcare
providers.
Traditional
treatment
methods,
including
medication
therapy,
remain
vital,
but
there
increasing
interest
in
the
application
of
artificial
intelligence
(AI)
to
enhance
BD
management.
AI
has
potential
improve
mood
episode
prediction,
personalize
plans,
provide
real-time
support,
offering
new
opportunities
managing
more
effectively.
Our
primary
objective
was
explore
role
transforming
management
BD,
specifically
tracking,
personalized
regimens.
Methods:
To
management,
we
conducted
review
recent
literature
using
key
search
terms.
We
included
studies
discussed
applications
personalization.
The
were
selected
based
on
their
relevance
AI's
with
attention
PICO
criteria:
Population-individuals
diagnosed
BD;
Intervention-AI
tools
personalization,
support;
Comparison-traditional
methods
(when
available);
Outcome-measures
effectiveness,
improvements
patient
care.
Results:
findings
from
research
reveal
promising
developments
use
Studies
suggest
AI-powered
can
enable
proactive
care,
improving
outcomes
reducing
burden
professionals.
ability
analyze
data
wearable
devices,
smartphones,
even
social
media
platforms
provides
valuable
insights
early
detection
dynamic
adjustments.
Conclusions:
While
still
its
stages,
it
presents
transformative
However,
further
development
are
crucial
fully
realize
supporting
optimizing
efficacy.
Language: Английский
Application of the Random Forest Algorithm for Accurate Bipolar Disorder Classification
Miguel Suárez,
No information about this author
Ana M. Torres,
No information about this author
P Blasco-Segura
No information about this author
et al.
Life,
Journal Year:
2025,
Volume and Issue:
15(3), P. 394 - 394
Published: March 3, 2025
Bipolar
disorder
(BD)
is
a
complex
psychiatric
condition
characterized
by
alternating
episodes
of
mania
and
depression,
posing
significant
challenges
for
accurate
timely
diagnosis.
This
study
explores
the
use
Random
Forest
(RF)
algorithm
as
machine
learning
approach
to
classify
patients
with
BD
healthy
controls
based
on
electroencephalogram
(EEG)
data.
A
total
330
participants,
including
euthymic
controls,
were
analyzed.
EEG
recordings
processed
extract
key
features,
power
in
frequency
bands
complexity
metrics
such
Hurst
Exponent,
which
measures
persistence
or
randomness
time
series,
Higuchi’s
Fractal
Dimension,
used
quantify
irregularity
brain
signals.
The
RF
model
demonstrated
robust
performance,
achieving
an
average
accuracy
93.41%,
recall
specificity
exceeding
93%.
These
results
highlight
algorithm’s
capacity
handle
complex,
noisy
datasets
while
identifying
features
relevant
classification.
Importantly,
provided
interpretable
insights
into
physiological
markers
associated
BD,
reinforcing
clinical
value
diagnostic
tool.
findings
suggest
that
reliable
accessible
method
supporting
diagnosis
complementing
traditional
practices.
Its
ability
reduce
delays,
improve
classification
accuracy,
optimize
resource
allocation
make
it
promising
tool
integrating
artificial
intelligence
care.
represents
step
toward
precision
psychiatry,
leveraging
technology
understanding
management
mental
health
disorders.
Language: Английский