Journal of Drug Research in Ayurvedic Sciences,
Journal Year:
2024,
Volume and Issue:
9(4), P. 264 - 272
Published: July 1, 2024
Abstract
BACKGROUND:
The
ancient
medicinal
herb
known
as
croton
joufra,
which
originated
in
northeastern
India,
is
still
used
today
folk
medicine
to
treat
a
wide
range
of
illnesses.
Phytochemicals
are
naturally
occurring
active
compounds
found
plants
that
provide
various
biological
activities
humans
and
animals.
METHODS:
Soxhlet
extraction
was
prepare
extracts
three
different
solvents
(chloroform,
methanol,
50%
ethanol).
Total
alkaloid
total
tannin
were
calculated
using
the
simple
titrimetric
method.
Folin
Ciocalteu’s
colorimetric
method
estimate
phenol
content.
In
vitro
antioxidant
activity
evaluated
methods:
DPPH
free
radical
scavenging
assay,
hydrogen
peroxide
ABTS
assay.
Heat-induced
bovine
serum
albumin
(BSA)
denaturation
assay
for
evaluating
anti-inflammatory
activity.
antidiabetic
determined
by
alpha-amylase
inhibition
RESULTS:
Among
these
solvent
extracts,
high
amount
yield
hydroalcoholic
extract.
Based
on
qualitative
quantitative
tests
plant
it
shown
contained
higher
alkaloids
(162.33
±
0.96
mg/g
dry
extract),
phenols
(205.30
0.95
extract
gallic
acid
equivalent),
tannins
(214.50
0.95mg/g
extract)
compared
chloroform
methanolic
have
better
antioxidant,
anti-inflammatory,
than
standard
drugs
such
ascorbic
acid,
aspirin,
metformin.
CONCLUSION:
From
results
experiment,
concluded
among
(50%
ethanol)
contains
substantial
amounts
secondary
metabolites
alkaloids,
phenols,
tannins.
also
has
promising
pharmacological
properties.
So
Croton
joufra
leaves
may
be
raw
material
drug
development.
Zeitschrift für Physikalische Chemie,
Journal Year:
2024,
Volume and Issue:
unknown
Published: March 20, 2024
Abstract
Teff
(
Eragrostis
tef
)
is
known
as
a
staple
grain
crop
which
grown
edible
seeds,
remarkably
in
Ethiopia.
However,
after
removal
of
its
the
hay
obtained
from
this
crop,
are
considered
agro-waste.
Such
lignocellulosic
agro-waste
can
be
potentially
exploited
to
prepare
activated
carbon
treat
harmful
industrial
effluents
for
detoxification.
In
study,
(TH)
was
used
precursor
preparing
carbon.
The
using
H
2
SO
4
,
chemical
activation
carried
out
followed
by
carbonaceous
process
undertaken
prepared
(AC)
pyrolysis.
AC
modified
magnetized
and
characterized
various
characterization
methods.
Further,
bio-absorbent,
potency
adsorptive
Cu(II)
ions
ascertained.
Notably,
most
studied
important
factors
adsorption,
such
as,
initial
concentration
metal
ion,
adsorbent
dosage,
pH,
contact
time
were
subjected
optimization
response
surface
method
(RSM).
ensure
statistical
aforementioned
factors,
non-statistical
techniques,
genetic
algorithm
(GA)
artificial
neural
network
(ANN)
tools
have
been
executed.
addition,
use
Teff-hay
based
adsorption
evaluated
through
different
isotherms
kinetic
approaches.
Nanomaterials,
Journal Year:
2024,
Volume and Issue:
15(1), P. 26 - 26
Published: Dec. 27, 2024
This
review
explores
biochar’s
potential
as
a
sustainable
and
cost-effective
solution
for
remediating
organic
pollutants,
particularly
polycyclic
aromatic
hydrocarbons
(PAHs)
pesticides,
in
water.
Biochar,
carbon-rich
material
produced
from
biomass
pyrolysis,
has
demonstrated
adsorption
efficiencies
exceeding
90%
under
optimal
conditions,
depending
on
the
feedstock
type,
pyrolysis
temperature,
functionalization.
High
surface
area
(up
to
1500
m2/g),
porosity,
modifiable
functional
groups
make
biochar
effective
adsorbing
wide
range
of
contaminants,
including
toxic
metals,
nutrients.
Recent
advancements
production,
such
chemical
activation
post-treatment
modifications,
have
enhanced
capacities,
with
engineered
achieving
superior
performance
treating
industrial,
municipal,
agricultural
effluents.
However,
scaling
up
applications
laboratory
research
field-scale
wastewater
treatment
poses
significant
challenges.
These
include
inconsistencies
variable
environmental
high
cost
large-scale
logistical
challenges
handling
deploying
at
scale,
need
integration
existing
systems.
Such
impact
practical
implementation
biochar-based
remediation
technologies,
requiring
further
investigation
into
production
methods,
long-term
assessments,
field-level
optimization
strategies.
underscores
importance
addressing
these
barriers
highlights
offer
sustainable,
environmentally
friendly,
economically
viable
treatment.
Journal of Drug Research in Ayurvedic Sciences,
Journal Year:
2024,
Volume and Issue:
9(3), P. 173 - 181
Published: May 1, 2024
Abstract
BACKGROUND:
7,12-Dimethylbenz[a]anthracene
(DMBA)
is
a
known
mutagen,
teratogen,
and
toxicant
besides
being
significant
factor
responsible
for
skin
carcinogenesis.
During
carcinogenesis,
DMBA
its
metabolites
produce
excessive
free
radicals
oxidative
stress.
This
stress
further
targets
various
cell
organelles.
Consequences
of
the
damage
by
also
influence
vital
organs,
such
as
brain,
liver,
testis,
with
complex
reactions,
an
increase
in
mutation,
modification
membranes,
structural
proteins,
metabolic
enzymes,
signaling
proteins.
Therefore,
this
study
evaluated
possible
role
hydroethanolic
Murraya
koenigii
(L.)
Spreng.
leaves
extract
(HEMKLE)
upon
damages
incurred
testis
tissues
against
DMBA/12-
O
-tetradecanoyl
phorbol-13-acetate
(TPA)
tumor-bearing
mice.
METHODS:
Forty
male
LACA
mice
were
segregated
into
four
groups:
control,
DMBA/TPA,
HEMKLE,
HEMKLE
+
DMBA/TPA.
Skin
tumors
induced
(500
nmol/100
μL
acetone)
TPA
(1.7
acetone;
applied
topically).
RESULTS:
The
protective
response
(200
mg/kg
body
weight)
to
testicular
during
tumorigenesis
was
apparent
recovery
endogenous
antioxidant
along
histoarchitecture
DMBA/TPA
group
contrasted
group.
Furthermore,
group,
reduced
messenger
ribonucleic
acid
protein
expressions
proapoptotic
genes
(caspase-9
caspase-3)
enhancement
Bcl-2
observed,
proposing
anti-apoptotic
potential
tissues.
CONCLUSION:
could
be
used
nutraceutical
or
drug
protect
from
insults.
