Expression of periferal core molecular clock genes in oral mucosa depends on the chronotype in patients with maxillofacial cellulitis DOI Creative Commons
K. P. Lokes,

V. O. Lychman,

O. V. Izmailova

et al.

Journal of Oral Biology and Craniofacial Research, Journal Year: 2023, Volume and Issue: 13(5), P. 517 - 521

Published: June 16, 2023

Accurate determination of the patient's chronotype is one problems personalized medicine. Recent studies have shown that determining expression timing genes a valuable method can help gain molecular insight into intrinsic circadian timing. Odontogenic cellulitis very common pathology. Since acute inflammatory diseases are an urgent pathology, time surgical intervention correspond depend on hospitalization.

Language: Английский

Coupling between the cell cycle and the circadian clock: Lessons from computational modelling and consequences for cancer chronotherapy DOI
Didier Gonze

Current Opinion in Systems Biology, Journal Year: 2024, Volume and Issue: 37, P. 100507 - 100507

Published: Feb. 2, 2024

Language: Английский

Citations

2

Circadian clock disruption impairs immune oscillation in chronic endogenous hypercortisolism: a multi-level analysis from a multicentre clinical trial DOI Creative Commons
Valeria Hasenmajer, Emilia Sbardella, Francesca Sciarra

et al.

EBioMedicine, Journal Year: 2024, Volume and Issue: 110, P. 105462 - 105462

Published: Nov. 28, 2024

Language: Английский

Citations

2

An Overview of the Circadian Clock in the Frame of Chronotherapy: From Bench to Bedside DOI Creative Commons
Alan Vandenberghe, Marc Lefranc, Alessandro Furlan

et al.

Pharmaceutics, Journal Year: 2022, Volume and Issue: 14(7), P. 1424 - 1424

Published: July 6, 2022

Most living organisms in both the plant and animal kingdoms have evolved processes to stay tune with alternation of day night, optimize their physiology as a function light supply. In mammals, circadian clock relying on feedback loops between key transcription factors will thus control temporally regulated pattern expression most genes. Modern ways life highly altered synchronization human activities clocks. This review discusses links an rise pathologies. We then sum up proofs concept advocating for integration considerations chronotherapy health care, medicine, pharmacotherapy. Finally, we discuss current challenges that biology must face tools address them.

Language: Английский

Citations

11

Stabilization and Reconstruction of Sampled-Data Boolean Control Networks Under Noisy Sampling Interval DOI
Liangjie Sun, Wai‐Ki Ching

IEEE Transactions on Automatic Control, Journal Year: 2022, Volume and Issue: 68(4), P. 2444 - 2451

Published: May 10, 2022

In this article, we consider stabilization and reconstruction of sampled-data Boolean control networks (BCNs) under noisy sampling interval. A BCN interval is first converted into a probabilistic network (PBN). We then obtain some necessary sufficient conditions for global stochastic stability the considered two types intervals. However, in analyzing large-scale BCNs interval, using abovementioned conditions, leads to huge computational cost. Therefore, BCN, have transform it size-reduced logical network. Then, by studying network, are obtained. Moreover, based on given steady-state probabilities transformed PBN, problem can be well-solved as linear programming problem. Notably, method presented here also applicable BCNs.

Language: Английский

Citations

11

Expression of periferal core molecular clock genes in oral mucosa depends on the chronotype in patients with maxillofacial cellulitis DOI Creative Commons
K. P. Lokes,

V. O. Lychman,

O. V. Izmailova

et al.

Journal of Oral Biology and Craniofacial Research, Journal Year: 2023, Volume and Issue: 13(5), P. 517 - 521

Published: June 16, 2023

Accurate determination of the patient's chronotype is one problems personalized medicine. Recent studies have shown that determining expression timing genes a valuable method can help gain molecular insight into intrinsic circadian timing. Odontogenic cellulitis very common pathology. Since acute inflammatory diseases are an urgent pathology, time surgical intervention correspond depend on hospitalization.

Language: Английский

Citations

5