Published: Jan. 1, 2024
Language: Английский
International Journal of Cancer, Journal Year: 2023, Volume and Issue: 153(10), P. 1734 - 1745
Published: Aug. 2, 2023
Vulvar cancer is an uncommon malignancy. alarmed the public health problem in terms of cost diagnostic and medical treatments psychical females. Our study aims to provide a thorough analysis global disease burden, related risk factors temporal incidence trends vulvar population subgroups. Data from Global Cancer Observatory Incidence Five Continents Plus were used for incidence. Age-standardized rates (ASR) depict cancer. The 10-year trend was assessed using joinpoint regression with average annual percentage change 95% confidence intervals various age groups, while its correlations investigated linear regression. Higher ASR found Western Europe (2.4), Northern America (1.9), Australia New Zealand (1.8) Eastern Africa (1.4). associated higher gross domestic product per capita, Human Development Index, prevalence smoking, alcohol drinking, unsafe sex human immunodeficiency virus infection. overall increasing. An increasing older females mixed observed younger burden follows bimodal pattern according two histologic pathways, affecting women both developed developing regions. Smoking cessation, education papillomavirus vaccination programs should be promoted among general population. Subsequent studies can done explore reasons behind
Language: Английский
Citations
8
Revista Brasileira Ginecologia e Obstetrícia, Journal Year: 2022, Volume and Issue: 44(10), P. 962 - 971
Published: Sept. 29, 2022
To explore the main sexuality complaints of gynecologic cancer survivors after treatment and to identify care strategies provided. Searches were conducted in six electronic databases: Scopus, Web Science, LILACS, MEDLINE, PsychINFO, EMBASE. Articles published between 2010 2020 selected following descriptors used English language: female genital neoplasms gynaecological cancer. The methodological quality studies Mixed Methods Appraisal Tool (MMAT). primary data extracted were: names authors, year publication, country origin, objective type study, collection instrument, sample size age range, types cancer, symptoms affected with adopted. A total 34 out 2,536 screened articles included. found for patient patient-clinician communication, practices care, individualized plan, multiprofessional team support, development rehabilitation programs. For most common are pelvic physiotherapy sessions use vaginal gels moisturizers. identified scientific literature low libido lack interest sexual activity, dryness, pain during intercourse, stenosis. Different may be adopted, such as follow-up a multidisciplinary health programs, which could minimize these ensure life patients. Explorar principais queixas da sexualidade com sobreviventes de câncer ginecológico após o tratamento e identificar estratégias cuidados prestados. As buscas foram realizadas em seis bases eletrônicas: PsychINFO SELEçãO DOS ESTUDOS: Foram selecionados artigos publicados entre os descritores utilizados (em inglês) qualidade metodológica dos estudos utilizou ferramenta Os dados extraídos foram: nomes autores, ano publicação, país origem, objetivo tipo estudo, instrumento para coleta dados, tamanho amostra faixa etária, tipos câncer, sintomas acometidos adotadas. SíNTESE DADOS: Dos identificados, incluídos. encontradas aos pacientes comunicação paciente-médico, práticas sexuais, plano individualizado, apoio equipes multiprofissionais desenvolvimento programas reabilitação. Para sexualidade, mais comuns são sessões fisioterapia pélvica uso géis vaginais hidratantes. CONCLUSãO: identificadas na literatura científica baixa falta interesse atividade sexual, secura vaginal, dor durante relação estenose. Diferentes podem ser adotadas, como acompanhamento uma equipe saúde multidisciplinar reabilitação quais poderiam minimizar estes garantir vida pacientes.
Language: Английский
Citations
11
Cancers, Journal Year: 2023, Volume and Issue: 15(12), P. 3079 - 3079
Published: June 7, 2023
Electrochemotherapy is a local ablative therapy used for the treatment of various superficial and deep-seated tumors. involves application electric pulses locally to tumors destabilize cell membranes facilitate entry cytotoxic drugs, thereby enhancing their cytotoxicity locally. The aim our study investigate safety feasibility electrochemotherapy in patients with vulvar cancer recurrence nonpalliative purposes. Ten single were treated intravenous bleomycin, followed by (electrochemotherapy) tumor. Adverse events determined using National Cancer Institute’s Common Terminology Criteria Events (CTCAE) version 5.0. treating was an appropriate selection electrodes based on size location tumor margins included. feasible all patients. No electrochemotherapy-related or other serious adverse occurred. Our data suggest that safe technique Based results, might be viable therapeutic tool who would otherwise undergo surgery involving mutilation external genitalia.
Language: Английский
Citations
6
Journal of Lower Genital Tract Disease, Journal Year: 2023, Volume and Issue: unknown
Published: Oct. 31, 2023
Abstract Objectives The objective of this study is to investigate vulvovaginal disease (VVD) awareness in Italian obstetrics and gynecology (Ob/Gyn) residents. Materials Methods A 25-question survey on VVD basic knowledge (17 questions) willingness improve it (8 was distributed through Ob/Gyn resident online group chats, from different Universities January 2023. total number 250 residents were invited participate; 124 responses obtained (response rate: 50%). Data collected analyzed using descriptive statistics REDCap. Results Overall, 87 the respondents (70%) fully completed questionnaire represented group. Residents among years residency: 15% first year, 31% second 23% third 11% fourth 20% fifth year. Most (60%) never attended a clinic during residency, with an increasing percentage attendance later residency (15% at year vs 65% fifth). Participants reported low vulvar precancerous lesions vulvoscopy but better vaginitis, self-examination, lichen sclerosus. Of respondents, 50% not satisfied education provided more than 60% lacked confidence managing VVD. All participants expressed strong desire their skills, 100% agreeing that every gynecologist should know “basics” 98% wanting webinars (45%), lessons (34%), newsletters, videos (19%). Conclusion Our findings indicate significant need Further efforts are necessary provide information about comprehensive training programs Universities.
Language: Английский
Citations
6
Sexual Medicine Reviews, Journal Year: 2024, Volume and Issue: 12(2), P. 142 - 153
Published: Jan. 5, 2024
Language: Английский
Citations
1
Springer eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 26
Published: Jan. 1, 2024
Language: Английский
Citations
1
Asian Pacific Journal of Cancer Care, Journal Year: 2024, Volume and Issue: 9(1), P. 125 - 132
Published: Feb. 10, 2024
Vulvar cancer remains a significant health concern for women worldwide, it provides comprehensive overview of biomarkers in vulvar cancer, focusing on the significance EGFR, GLUT1, MUC1, and MRP1. It explores their prognostic value, pathophysiology delves into intricate landscape P16, PD-L1, P53 biomarkers. The article aims to elucidate roles these predicting outcomes, offering insights potential as indicators cancer. This analysis contributes evolving understanding molecular markers context prognosis informs future research directions field.
Language: Английский
Citations
1
Acta Oncologica, Journal Year: 2024, Volume and Issue: 63, P. 351 - 357
Published: May 21, 2024
Electrochemotherapy (ECT) is a combined treatment method based on electroporation and simultaneous chemotherapy. In cases where radiotherapy has previously been used, surgery often the only option for vulvar cancer recurrence with potential resection of clitoris, vagina, urethra or anal sphincter. The unique advantage ECT its selectivity cells while sparing surrounding healthy tissue. aim study was to compare non-palliative purposes surgical treatment.
Language: Английский
Citations
1
Bulletin of Rehabilitation Medicine, Journal Year: 2024, Volume and Issue: 23(5), P. 52 - 60
Published: Nov. 26, 2024
Introduction. Surgical treatment of vulvar cancer (VC) entails mental and somatic disturbances due to pain, body image changes, sexual dysfunction, which are closely associated with impaired social functioning reduced overall quality life. However, the results evaluating impact rehabilitation programmes on various components life in these patients remain limited. Aim. evaluate effectiveness programs relation psycho-emotional sphere during 36 months following surgical early-stage VC. Materials methods. The randomized controlled study included female VC, divided into two parallel groups those who received a personalized program comprehensive (VC-1) according general principles regulated national clinical guidelines (VC-2). each were randomly assigned VC-1 VC-2 groups. control group 80 women without cancer. was recommended physical activity, psychological support, anti-edema therapy for lymphostasis. additionally lifestyle modification, cognitive-behavioral therapy, intimate hygiene training, magnesium, vitamin B6 folic acid supplementation, correction disorders, phytotherapy physiotherapy from 3rd month, climatotherapy landscape 6th month. “Well-being, Activity, Mood” (WAM) questionnaire administered at preoperative visit, 1 week, 1, 3, 6, 12, 24 after surgery. Scores presented as Me [Q25; Q75], differences considered significant p 0.05. Results. In group, scores all WAM domains within normal values throughout study. 1st week surgery, well-being activity decreased unfavorable both Mood, however, showed positive dynamics compared baseline. Subsequently, improvement significantly faster more pronounced than reaching range favorable by 12th but not group. Conclusion. efficacy well-being, mood basic rehabilitation. measures should be continued one year
Language: Английский
Citations
1
Cancers, Journal Year: 2022, Volume and Issue: 14(7), P. 1695 - 1695
Published: March 26, 2022
(1) Background: plastic reconstruction in vulvar surgery can lead to a better treatment outcome than primary closure. This study aims compare the preoperative parameters (co-morbidities and tumor size) postoperative results (tumor free margins wound healing) between closure reconstructive after cancer surgery; (2) Methods: this is retrospective analysis of prospectively collected data from 2009 2021 at tertiary institution; (3) Results: 177 patients were included final (51 had PC 126 RS). About half (49%) no co-morbidities (p = 0.043). The RS group 45 mm median maximal diameter compared group's 23 0.013). More 90% 80% tumor-free 0.1). Both groups anterior excision as most common (52.4% vs. 23.5% PC; p 0.001). identical rates healing disorders. In follow-up 39 months; recurrent disease was found 10.3% 0.012). terms overall survival there significant difference both groups; (4) Conclusions: enables enhanced complete resection larger tumors with anatomical restoration comparable recovery comparison lower recurrence rate despite increased volume.
Language: Английский
Citations
6