La radiologia medica, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 24, 2024
Language: Английский
La radiologia medica, Journal Year: 2023, Volume and Issue: 128(6), P. 775 - 783
Published: May 15, 2023
Language: Английский
Citations
3
American Journal of Roentgenology, Journal Year: 2023, Volume and Issue: 221(6), P. 806 - 816
Published: June 28, 2023
BACKGROUND. Brain tumors induce language reorganization, which may influence the extent of resection in surgical planning. Direct cortical stimulation (DCS) allows definitive mapping during awake surgery by locating areas speech arrest (SA) surrounding tumor. Although functional MRI (fMRI) combined with graph theory analysis can illustrate whole-brain network few studies have corroborated these findings DCS intraoperative and clinical performance.
Language: Английский
Citations
2
Clinical Nuclear Medicine, Journal Year: 2024, Volume and Issue: 49(9), P. 822 - 829
Published: May 1, 2024
Purpose 18 F-FDG PET captures the relationship between glucose metabolism and synaptic activity, allowing for modeling brain function through metabolic connectivity. We investigated tumor-induced modifications of Patients Methods Forty-three patients with left hemispheric tumors PET/MRI were retrospectively recruited. included 37 healthy controls (HCs) from database CERMEP-IDB-MRXFDG. analyzed whole right versus hemispheres connectivity in HC, frontal temporal tumors, active radiation necrosis, high Karnofsky performance score (KPS = 100) low KPS < 70). Results compared 2-sided t test ( P 0.05). Twenty high-grade glioma, 4 low-grade 19 metastases included. The patients’ whole-brain network displayed lower metrics HC 0.001), except assortativity betweenness centrality 0.001). showed decreased similarity, 0.01), exception 0.002). did not show significant differences. Frontal higher 0.001) than but 4.5 −7 ). distance local efficiency rich club coefficient 0.0048), clustering 0.00032), 0.008), similarity 0.0027) KPS. tumor(s) (14/43) demonstrated significantly necroses. Conclusions Tumors cause reorganization networks, characterized by formation new connections centrality. retained a more efficient, centralized, segregated tumors. Stronger was associated
Language: Английский
Citations
0
NeuroImage Clinical, Journal Year: 2024, Volume and Issue: 44, P. 103689 - 103689
Published: Jan. 1, 2024
We explored the functional outcome following awake surgery and Real-Time Neuropsychological Testing (RTNT) in left insula. carried out a longitudinal investigation by comparing patients' language profile, and, particular, object-naming skills associated fMRI network, of pre-surgery follow-up (i.e., few months after surgery) group 23 patients harboring left-sided low grade glioma centered to insulo-temporal area. Tumor resection, performed while continuously monitoring performance RNTN, was high (median = 92 %). From neuropsychological viewpoint, almost all displayed preserved naming general, both before at follow-up, when they recovered from transient impairment recorded immediately surgery. imaging networks two assessment times were equivalent, with non-parametric analyses showing brain remodeling involving perilesional areas preoperatively contralesional, healthy, insula follow-up. discussed anatomo-functional mechanisms that contributed preservation cognitive pattern as observed this study, particular focus on promising plasticity potential insular In we commented that, least our patient series applying an optimized surgical procedure, safe generally functions.
Language: Английский
Citations
0
La radiologia medica, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 24, 2024
Language: Английский
Citations
0