Hide-and-Seek With Spindle-Cell-Component-Poor Metaplastic Thymoma DOI Open Access

Gintarė Ražanskienė,

Vilhelmas Landsbergis,

Vytenis Bertašius

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: May 12, 2024

Metaplastic thymoma is a rare biphasic thymic tumor with indolent behavior and recurrent YAP1::MAML2 gene rearrangement. Although the diagnosis of this usually straightforward based on hematoxylin eosin (H&E) findings alone, cases scant spindle-cell ("pseudosarcomatous stroma") components can be easily confused more commonly occurring type A thymoma. We present case metaplastic sparse stroma-like component, discussing its histological immunohistochemical hints drawing attention to visual similarity This also first published associated psoriasis.

Language: Английский

Immunohistochemistry for YAP1 N-terminus and C-terminus highlights metaplastic thymoma and high-grade thymic epithelial tumors by different staining patterns DOI
Yosuke Yamada, Stefan Küffer,

Christian Sauer

et al.

Virchows Archiv, Journal Year: 2024, Volume and Issue: 485(3), P. 461 - 469

Published: Aug. 3, 2024

Language: Английский

Citations

1
Hide-and-Seek With Spindle-Cell-Component-Poor Metaplastic Thymoma DOI Open Access

Gintarė Ražanskienė,

Vilhelmas Landsbergis,

Vytenis Bertašius

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: May 12, 2024

Metaplastic thymoma is a rare biphasic thymic tumor with indolent behavior and recurrent YAP1::MAML2 gene rearrangement. Although the diagnosis of this usually straightforward based on hematoxylin eosin (H&E) findings alone, cases scant spindle-cell ("pseudosarcomatous stroma") components can be easily confused more commonly occurring type A thymoma. We present case metaplastic sparse stroma-like component, discussing its histological immunohistochemical hints drawing attention to visual similarity This also first published associated psoriasis.

Language: Английский

Citations

0