
Diagnostics, Journal Year: 2024, Volume and Issue: 14(16), P. 1799 - 1799
Published: Aug. 16, 2024
Cutaneous squamous cell carcinoma (cSCC) is the second-most-prevalent malignancy in humans. A delayed diagnosis of cSCC leads to heightened invasiveness and positive surgical margins. Bowen’s disease (BD) represents an early form presents as a small erythematous, photo-distributed, psoriasiform plaque. Although certain dermoscopy features BD are quite characteristic, histopathology remains gold standard for provides severity-scoring system that assists guiding appropriate treatment strategies. The classification precancerous lesions vulva penis has undergone multifarious transformations due variations clinical histopathological characteristics. Presently, erythroplasia Queyrat categorized variant penile intraepithelial neoplasia (PeIN). diagnoses vulvar (VIN) PeIN present significant challenges typically necessitate one or more biopsies, potentially guided by dermoscopy. Aceto-white testing demonstrates notably high negative predictive value genital lesions. Histopathological examination gold-standard VIN PeIN, while p16 p53 immunostainings alongside HPV provide crucial diagnostic clues. histopathologic features, degree differentiation, associations with lichen planus, sclerosus, guide selection conservative treatments excision.
Language: Английский