The Relationship Between Cervicovaginal Infection, Human Papillomavirus Infection and Cervical Intraepithelial Neoplasia in Romanian Women DOI Creative Commons

Anca Daniela Brăila,

Cristian-Viorel Poalelungi,

Cristina-Crenguța Albu

et al.

Diseases, Journal Year: 2025, Volume and Issue: 13(1), P. 18 - 18

Published: Jan. 16, 2025

Cervical intraepithelial neoplasia (CIN) is a premalignant cervical condition closely linked to persistent high-risk HPV infection, major risk factor for cancer. This study aims investigate the relationship between cervicovaginal infections, and CIN development in 94 Romanian women with lesions. Comprehensive assessments included genotyping, cytology, colposcopy, histopathology. In 53.20% of cases, vaginal infections were identified, Candida albicans most frequently associated HPV. Histopathology revealed 48.94% low-grade CIN, 42.55% high-grade 8.51% invasive carcinoma. There was strong correlation types (especially 16 18), colposcopic findings, histopathology, age. emphasizes mutual effect infection increasing developing cancer among women. Persistent types, particularly 18, has been confirmed as primary driver progression.

Language: Английский

The Relationship Between Cervicovaginal Infection, Human Papillomavirus Infection and Cervical Intraepithelial Neoplasia in Romanian Women DOI Creative Commons

Anca Daniela Brăila,

Cristian-Viorel Poalelungi,

Cristina-Crenguța Albu

et al.

Diseases, Journal Year: 2025, Volume and Issue: 13(1), P. 18 - 18

Published: Jan. 16, 2025

Cervical intraepithelial neoplasia (CIN) is a premalignant cervical condition closely linked to persistent high-risk HPV infection, major risk factor for cancer. This study aims investigate the relationship between cervicovaginal infections, and CIN development in 94 Romanian women with lesions. Comprehensive assessments included genotyping, cytology, colposcopy, histopathology. In 53.20% of cases, vaginal infections were identified, Candida albicans most frequently associated HPV. Histopathology revealed 48.94% low-grade CIN, 42.55% high-grade 8.51% invasive carcinoma. There was strong correlation types (especially 16 18), colposcopic findings, histopathology, age. emphasizes mutual effect infection increasing developing cancer among women. Persistent types, particularly 18, has been confirmed as primary driver progression.

Language: Английский

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