Cells, Journal Year: 2025, Volume and Issue: 14(2), P. 118 - 118
Published: Jan. 14, 2025
Recent advances in molecular genetics, particularly identifying and characterizing genetic abnormalities within mesenchymal neoplasms, have led to a more comprehensive evolving classification system. Modern technological developments cytogenetics next-generation sequencing enabled the analysis of small clinical samples, expanded our understanding tumor biology, improved diagnostic, prognostic, predictive precision by targeted alterations, confirming presence fusion transcripts, and/or revealing overexpression specific genes their targets. In this review, we focus specifically on GLI1-rearranged enteric tumor, recent clinicopathological entity that has emerged expanding tumors. Herein, aim explore histopathological features, characteristics, outcomes these Due rarity extensive overlapping features with other continued research systematic documentation tumors is necessary better understand biological behavior, develop accurate prognostic indicators, establish optimal treatment strategies.
Language: Английский