Modern Treatment of Skeletal Metastases: Multidisciplinarity and the Concept of Oligometastasis in the Recent Literature DOI Creative Commons
Giulia Trovarelli, Arianna Rizzo,

Felicia Deborah Zinnarello

et al.

Current Oncology, Journal Year: 2025, Volume and Issue: 32(4), P. 226 - 226

Published: April 11, 2025

Bone metastases are a major concern in cancer management since they significantly contribute to morbidity and mortality. Metastatic lesions, commonly arising from breast, prostate, lung, kidney cancers, affect approximately 25% of patients, leading severe complications such as pain, fractures, neurological deficits. This narrative review explores contemporary approaches bone metastases, emphasizing multidisciplinary strategy the evolving concept oligometastatic disease. Oligometastases, defined by limited metastatic spread (1–5 lesions), offer potential window for curative treatment through aggressive interventions, including stereotactic ablative radiotherapy resection surgery. Tumor boards, integrating systemic therapies with local crucial optimize treatment. Despite promising results, gaps remain defining optimal sequences refining patient selection criteria. Future research should focus on personalized approaches, leveraging biomarkers advanced imaging enhance outcomes quality life patients metastases.

Language: Английский

European Association of Urology Guidelines on Muscle-invasive and Metastatic Bladder Cancer: Summary of the 2025 Guidelines DOI
Antoine G. van der Heijden,

Harman Max Bruins,

Albert Carrión

et al.

European Urology, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

1
Modern Treatment of Skeletal Metastases: Multidisciplinarity and the Concept of Oligometastasis in the Recent Literature DOI Creative Commons
Giulia Trovarelli, Arianna Rizzo,

Felicia Deborah Zinnarello

et al.

Current Oncology, Journal Year: 2025, Volume and Issue: 32(4), P. 226 - 226

Published: April 11, 2025

Bone metastases are a major concern in cancer management since they significantly contribute to morbidity and mortality. Metastatic lesions, commonly arising from breast, prostate, lung, kidney cancers, affect approximately 25% of patients, leading severe complications such as pain, fractures, neurological deficits. This narrative review explores contemporary approaches bone metastases, emphasizing multidisciplinary strategy the evolving concept oligometastatic disease. Oligometastases, defined by limited metastatic spread (1–5 lesions), offer potential window for curative treatment through aggressive interventions, including stereotactic ablative radiotherapy resection surgery. Tumor boards, integrating systemic therapies with local crucial optimize treatment. Despite promising results, gaps remain defining optimal sequences refining patient selection criteria. Future research should focus on personalized approaches, leveraging biomarkers advanced imaging enhance outcomes quality life patients metastases.

Language: Английский

Citations

0