Smart Bioelectronics for Real-Time Diagnosis and Therapy of Body Organ Functions DOI
Lili Guo,

Hin Kiu Lee,

Suyoun Oh

et al.

ACS Sensors, Journal Year: 2025, Volume and Issue: unknown

Published: May 1, 2025

Noncommunicable diseases (NCDs) associated with cardiovascular, neurological, and gastrointestinal disorders remain a leading cause of global mortality, sounding the alarm for urgent need better diagnostic therapeutic solutions. Wearable implantable biointegrated electronics offer groundbreaking solution, combining real-time, high-resolution monitoring innovative treatment capabilities tailored to specific organ functions. In this comprehensive review, we focus on affecting brain, heart, organs, bladder, adrenal gland, along their physiological parameters. Additionally, provide an overview characteristics these parameters explore potential bioelectronic devices in situ sensing applications highlight recent advancements deployment across organs. Finally, analyze current challenges prospects implementing closed-loop feedback control systems integrated sensor-therapy applications. By emphasizing organ-specific advocating systems, review highlights future bioelectronics address needs serves as guide researchers navigating interdisciplinary fields diagnostics, therapeutics, personalized medicine.

Language: Английский

Quercetin-functionalized nanomaterials: Innovative therapeutic avenues for Alzheimer's disease management DOI
Jinjin Pei,

Ranil Vikraman Kumarasamy,

Selvaraj Jayaraman

et al.

Ageing Research Reviews, Journal Year: 2025, Volume and Issue: unknown, P. 102665 - 102665

Published: Jan. 1, 2025

Language: Английский

Citations

8
Emerging nanoplatforms towards microenvironment-responsive glioma therapy DOI

Nigam Sekhar Tripathy,

Liza Sahoo,

Safal Kumar Paikray

et al.

Medical Oncology, Journal Year: 2025, Volume and Issue: 42(2)

Published: Jan. 15, 2025

Language: Английский

Citations

1
Nanoparticle Strategies for Treating CNS Disorders: A Comprehensive Review of Drug Delivery and Theranostic Applications DOI Open Access
Corneliu Toader, Adrian Dumitru,

Lucian Eva

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(24), P. 13302 - 13302

Published: Dec. 11, 2024

This review aims to address the significant challenges of treating central nervous system (CNS) disorders such as neurodegenerative diseases, strokes, spinal cord injuries, and brain tumors. These are difficult manage due complexity disease mechanisms protective blood–brain barrier (BBB), which restricts drug delivery. Recent advancements in nanoparticle (NP) technologies offer promising solutions, with potential applications delivery, neuroprotection, neuroregeneration. By examining current research, we explore how NPs can cross BBB, deliver medications directly targeted CNS regions, enhance both diagnostics treatment. Key NP strategies, passive targeting, receptor-mediated transport, stimuli-responsive systems, demonstrate encouraging results. Studies show that may improve minimize side effects, increase therapeutic effectiveness models Alzheimer’s, Parkinson’s, stroke, glioblastoma. thus represent a approach for disorder management, combining delivery diagnostic capabilities enable more precise effective treatments could significantly benefit patient outcomes.

Language: Английский

Citations

4
Intranasal Delivery of Temozolomide and Desloratadine for Brain Tumour Therapy: A Cellular Study on Nasal Epithelial Toxicity, Transport, and Permeability DOI
Chun Y. Wong,

Elaine Leite,

Hui Xin Ong

et al.

Journal of Pharmaceutical Sciences, Journal Year: 2025, Volume and Issue: unknown, P. 103795 - 103795

Published: April 1, 2025

Language: Английский

Citations

0
Functionalized Nanoparticles: A Promising Approach for Effective Management of Alzheimer’s Disease DOI

Subhasri Bogadi,

Mahendran Bhaskaran, Ravichandran Veerasamy

et al.

Molecular Neurobiology, Journal Year: 2025, Volume and Issue: unknown

Published: April 16, 2025

Language: Английский

Citations

0
Innovative approaches to blood-brain barrier modelling: The chip revolution DOI Creative Commons

Avijit Bej,

Nawajes Mandal, Anwesha Das

et al.

Next Nanotechnology, Journal Year: 2025, Volume and Issue: 7, P. 100171 - 100171

Published: Jan. 1, 2025

Language: Английский

Citations

0
Smart Bioelectronics for Real-Time Diagnosis and Therapy of Body Organ Functions DOI
Lili Guo,

Hin Kiu Lee,

Suyoun Oh

et al.

ACS Sensors, Journal Year: 2025, Volume and Issue: unknown

Published: May 1, 2025

Noncommunicable diseases (NCDs) associated with cardiovascular, neurological, and gastrointestinal disorders remain a leading cause of global mortality, sounding the alarm for urgent need better diagnostic therapeutic solutions. Wearable implantable biointegrated electronics offer groundbreaking solution, combining real-time, high-resolution monitoring innovative treatment capabilities tailored to specific organ functions. In this comprehensive review, we focus on affecting brain, heart, organs, bladder, adrenal gland, along their physiological parameters. Additionally, provide an overview characteristics these parameters explore potential bioelectronic devices in situ sensing applications highlight recent advancements deployment across organs. Finally, analyze current challenges prospects implementing closed-loop feedback control systems integrated sensor-therapy applications. By emphasizing organ-specific advocating systems, review highlights future bioelectronics address needs serves as guide researchers navigating interdisciplinary fields diagnostics, therapeutics, personalized medicine.

Language: Английский

Citations

0