Exploring 4th Generation EGFR Inhibitors: A Review of Clinical Outcomes and Structural Binding Insights.

European Journal of Pharmacology, Journal Year: 2025, Volume and Issue: unknown, P. 177608 - 177608

Published: April 1, 2025

Language: Английский

Artificial Intelligence-Based Methods for Drug Repurposing and Development in Cancer

Applied Sciences, Journal Year: 2025, Volume and Issue: 15(5), P. 2798 - 2798

Published: March 5, 2025

Drug discovery and development remains a complex time-consuming process, often hindered by high costs low success rates. In the big data era, artificial intelligence (AI) has emerged as promising tool to accelerate optimize these processes, particularly in field of oncology. This review explores application AI-based methods for drug repurposing natural product-inspired design cancer, focusing on their potential address challenges limitations traditional approaches. We delve into various approaches (machine learning, deep others) that are currently being employed purposes, role experimental techniques By systematically reviewing literature, we aim provide comprehensive overview current state AI-assisted cancer workflows, highlighting AI’s contributions accelerating development, reducing costs, improving therapeutic outcomes. also discusses opportunities associated with integration AI pipeline, such quality, interpretability, ethical considerations.

Language: Английский

Combination Therapies in Drug Repurposing: Personalized Approaches to Combatting Leukaemia and Multiple Myeloma

Advances in experimental medicine and biology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский