Palladium Supported on Silk Fibroin as Efficient Catalyst for Sonogashira Coupling and Sonogashira‐Cacchi Type Annulation

European Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 27(40)

Published: Aug. 9, 2024

Abstract A palladium catalyst supported on silk fibroin (Pd/SF) has been tested in the Sonogashira coupling reactions of a wide range aryl iodides and terminal alkynes. The best catalytic performance was obtained at 90 °C using only 0.25 mol % metal loading under copper‐free conditions, presence H 2 O/EtOH (3 : v/v) solvent mixture triethylamine as base, affording products good yields. Pd/SF‐based protocol then successfully extended to synthesis benzofurans through Sonogashira‐Cacchi type annulation 2‐iodophenol with Preliminary investigations recyclability heterogeneous behaviour were performed: hot filtration test leaching evidenced small amount soluble active species into reaction mixture. Nevertheless, Pd/SF could be reused recharging it can recycled four consecutive runs no significant deactivation.

Language: Английский

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Metal‐Supported Heterogeneous Catalysts for the Synthesis of Nitrogen‐Containing Heterocycles: A Comprehensive Review

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(34)

Published: Sept. 9, 2024

Abstract The use of metals in the preparation heterocycles has become increasingly popular due to several key advantages as catalysts. These include recycling capability, eco‐friendliness, simplicity catalyst and separation, longer lifespan, abundance, higher yields. As a result their novel applications organic, inorganic, medicinal, industrial, polymer chemistry, material sciences, nanotechnology, biological processes, utilization nitrogen‐containing rapidly increased recent years. Various organic moieties are used therapeutic processes enhance effectiveness against bacterial viral diseases. This review covers imidazoles, triazoles, tetrazoles, pyridine derivatives, azo compounds, pyrimidines, quinoxalines, quinolines using heterogeneous It provides an overview current methodologies for metal‐assisted catalytic reactions, including product yield, operating temperature, solvents, among other factors. Heterogeneous catalyst‐mediated synthetic reactions offer advantages, particularly medicinal pharmaceuticals, industrial applications, by reducing time energy consumption. emphasizes advancements fabrication nitrogen utilizing catalysts, taking into account various economic, eco‐friendly, user‐friendly considerations. Additionally, it discusses benefits, reaction conditions, yields reported literature over past six

Language: Английский

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Preparation of Ca- and Na-Modified Activated Clay as a Promising Heterogeneous Catalyst for Biodiesel Production via Transesterification

Applied Sciences, Journal Year: 2022, Volume and Issue: 12(9), P. 4667 - 4667

Published: May 6, 2022

For efficient biodiesel production, an acid-activated clay (AC) modified by calcium hydroxide and sodium (CaNa/AC) was prepared as a catalyst. CaNa/AC Na/AC were characterized Hammett indicators, CO2-TPD, FT-IR, XRD, N2 adsorption techniques. The influence of catalyst dose, reaction temperature, methanol/oil molar ratio, time on the transesterification Jatropha oil studied. Due to introduction calcium, displayed higher activity stability, thereby achieving conversion 97% under optimal conditions maintaining over 80% after five successive reuses. accelerated temperature rose, apparent activation energy 75.6 kJ·mol−1. enhanced production ascribed increase in active sites basic strength. This study presents facile practical method for producing large-scale operation.

Language: Английский

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Magnetically Reusable Fe3O4‐CuO Nanoparticles as Catalysts for the Synthesis of Aryl‐Substituted Fluorescent Pyrazines for Fe Sensing and Ink Applications

European Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 27(31)

Published: June 18, 2024

Abstract The synthesis of substituted pyrazines from readily available methyl aryl/heteroaryl ketones and 1,2‐diamines was achieved using highly stable reusable ferrite‐stabilized copper nanoparticles (Fe 3 O 4 ‐CuO) as a catalyst. reaction proceeds through cascade imine formation–oxidative cyclization method under an oxygen atmosphere. nanocatalysts were recovered reused up to three consecutive cycles without any significant decrease in particle size, catalytic activity yield, evidenced by analytical techniques such transmission electron microscopy (TEM) powder X‐ray diffraction (PXRD). synthesized exhibited photophysical behaviour, displayed large Stokes shifts, explored fluorescent probes for the sensitive well selective “turn‐off” detection iron with limit 0.63 μM. sensing is also useful quantification spiked water samples. Furthermore, application luminescent ink successfully demonstrated.

Language: Английский

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Chiral Diketopyrrolo[3,4‐c]pyrrole‐1,2,3‐1H‐triazole Dyes with Highly Tuneable Properties in Solution and Thin Films

Chemistry - A European Journal, Journal Year: 2023, Volume and Issue: 29(34)

Published: March 23, 2023

We have studied the impact of achiral substituents on chiral supramolecular architectures diketopyrrolo[3,4-c]pyrrole-1,2,3-1H-triazole (DPP) dyes. decorated same DPP motif with substituent groups nitrogen atoms lactam moiety: hydrophobic n-octyl alkyl chain, hydrophilic tri(ethylene glycol) (TEG) chain and thermo-cleavable tert-butoxycarbonyl (t-Boc) carbamate group. In spite having identical conjugated chromophore appendages, in aggregated form three dyes displayed profoundly different optical, chiroptical, electrochemical thermal features. ECD measurements revealed differences aggregation modes, which would be inaccessible by most other techniques. found strong chiroptical features, major implications context organic opto-electronics development highly innovative technological applications.

Language: Английский

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“One-Pot” Construction of Networked AlCl3·6H2O@β-CD Composites by Mechanical Milling: A Green and Efficient Catalyst for the Synthesis of Bisindolylmethane Compounds

Catalysis Letters, Journal Year: 2023, Volume and Issue: 154(1), P. 270 - 279

Published: Feb. 18, 2023

Language: Английский

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One–Pot Three–Component Synthesis of 2,4,5–Triaryl Imidazoles using Fe3O4@BisImid−CuBr Nanocomposite as an Ecofriendly and Efficient Magnetically Reusable Catalyst

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(15)

Published: April 17, 2024

Abstract Imidazoles are one of the keys N‐heterocycle molecules that exist in structure many biomolecules. In this research project, we reported Fe 3 O 4 @BisImid−CuBr nanocomposite is an attractive and efficient nanomagnetic catalyst to afford 2,4,5–triaryl imidazoles through reactions 1,2–diketones aldehydes presence NH OAc under ecofriendly conditions. The was readily fabricated by a simple method from available reagents its analyzed spectroscopic techniques. SEM TEM images affirmed formation particles spherical shape nanometer–size. Under methodology, diverse library triaryl were afforded with high yields water. This synthetic methodology has significant features such as (a) purity products (b) suitable reaction time (c) use magnetic reusable nanocatalyst (d) reusability performance aqueous medium.

Language: Английский

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Efficient Synthesis of Bis(indolyl)methane Derivatives on Heterogeneous Ga‐MCM‐41‐SO₃H Catalyst under Mild Conditions

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(41)

Published: Oct. 28, 2024

Abstract We are reporting a convenient method for the synthesis of bis(indolyl)methane derivatives from relatively cheap and commercially available chemicals such as indoles aldehydes in one‐pot procedure using Ga‐MCM‐41‐SO 3 H heterogeneous catalyst. Notably, use this catalyst has resulted high yield products (up to 98 %) under mild conditions, was found be stable reusable, retaining its highly catalytic activity even after five runs. Interestingly, two alkaloids Arsindoline A Turbomycine B were successfully synthesized employment These findings suggest that could promising alternative traditional acid homogeneous catalysts derivatives, offering several advantages including ease separation reuse, stability, low toxicity.

Language: Английский

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Metal Promoted Cyclocarbonylation Reactions in the Synthesis of Heterocycles

Catalysts, Journal Year: 2022, Volume and Issue: 12(4), P. 353 - 353

Published: March 22, 2022

Oxygen and nitrogen heterocycle systems are found in a vast number of natural substrates biologically active molecules such as antimycotics, antibiotics, antitumors antioxidants, addition to pigments fluorophores [...]

Language: Английский

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Metal Promoted Cyclocarbonylation Reactions in the Synthesis of Heterocycles

MDPI eBooks, Journal Year: 2022, Volume and Issue: unknown

Published: April 4, 2022

This book is focused on metal-catalyzed cyclocarbonylation reactions applied to the synthesis of heterocyclic rings different sizes, including diastereoselective and enantioselective approaches, homogeneous heterogeneous metal catalysis, application these total natural products.

Language: Английский

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