Reaction Chemistry & Engineering, Journal Year: 2024, Volume and Issue: 10(3), P. 605 - 613
Published: Dec. 5, 2024
In an umbrella-shaped microchannel reactor, the continuous selective aerobic oxidation of toluene derivatives to aromatic aldehydes over a Co/Mn/Br catalytic system using acetic acid/water as solvent was studied.
Language: Английский
Soft Matter, Journal Year: 2023, Volume and Issue: 19(39), P. 7541 - 7549
Published: Jan. 1, 2023
The formation of macromolecularly enriched condensates through associative or segregative liquid-liquid phase separation phenomena is known to play a central role in controlling various cellular functions nature. potential spatially and temporally modulate multistep chemical reactions pathways has inspired the use phase-separated systems for development synthetic colloidal micro- nanoreactor systems. Here, we report rational synthetically minimal design strategy emulate intended spatiotemporal morphologically intricate structurally defined calcium alginate hydrogel microreactors possessing multicompartmentalized internal architectures. Specifically, implement thermal protocol achieve fine-control over inside complex aqueous emulsion droplet templates that are loaded with hydrophilic polymer mixtures. Subsequent gelation alginate-containing using novel freeze-thaw approach can be applied both scalable batch production more precise microfluidic methods yields particle replicas, which subcompartmentalized architectures retained. Larger active components compartments due their preferential solubility, show selective sequestration enzymes serves create desired microenvironments control tune reaction kinetics enzyme cascade by reducing mutual interference. This demonstration mitigating substrate inhibition based primarily on optimizing morphology offers new opportunities simple synthetically-minimal generation hydrogel-based synthesis microreactors.
Language: Английский
Citations
4
Bioprocess and Biosystems Engineering, Journal Year: 2023, Volume and Issue: 46(11), P. 1665 - 1676
Published: Oct. 10, 2023
Language: Английский
Citations
4
Chemical and Biochemical Engineering Quarterly, Journal Year: 2024, Volume and Issue: 37(4), P. 255 - 260
Published: Jan. 1, 2024
Although the range of applications for enzymatic reactions in organic solvents is <br /> rapidly expanding, this study focused on activity esterification lauric acid with benzyl alcohol, and thermostability lipase using poly(ethylene glycol) (PEG)-lipase complex molecular imprinting techniques. The catalytic was enhanced through PEG-lipase complex. operation particularly effective after forming kinetic analysis lipase-catalyzed revealed that increase rate imprinted lipases mainly due to higher maximum achieved by system. significantly improved at all temperatures (50~70 °C). After a complex, exhibited much reactivity compared native
Language: Английский
Citations
1
Micromachines, Journal Year: 2024, Volume and Issue: 15(2), P. 288 - 288
Published: Feb. 18, 2024
Microfluidic devices have attracted much attention in the current day owing to unique advantages they provide. However, their application for industrial use is limited due manufacturing limitations and high cost. Moreover, scaling-up process of microreactor has proven be difficult. Three-dimensional (3D) printing technology a promising solution above obstacles its ability fabricate complex structures quickly at relatively low Hence, combining microscale with 3D could enhance applicability microfluidic sector. In present work, 3D-printed single-channel immobilized enzyme volume capacity 30 μL was designed created one step via fused deposition modeling (FDM) technique, using polylactic acid (PLA) as material. The underwent surface modification chitosan, β-glucosidase from Thermotoga maritima covalently immobilized. biocatalyst retained almost 100% initial activity after incubation different temperatures, while it effectively reused up 10 successful reaction cycles. multi-channel parallel incorporating 36 channels developed, resulting significant increase enzymatic productivity.
Language: Английский
Citations
1
Industrial & Engineering Chemistry Research, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 21, 2024
Microreactors provide an enhanced mixing performance but suffer from low throughput. This work proposed a macro-microreactor with designed internals to achieve both process intensification and scale-up for the liquid–liquid homogeneous chemical processes. Numerical simulations utilizing computational fluid dynamics were conducted investigate mechanics properties of (feature size >2000 μm). Experimental validation using Villermaux–Dushman reaction demonstrated that this easily fabricated optimized helical-shaped internal achieved comparable performance, lower pressure drop, higher throughput compared typical microreactor smaller feature (1000 The would find more applications in industrial
Language: Английский
Citations
1
E3S Web of Conferences, Journal Year: 2023, Volume and Issue: 436, P. 10003 - 10003
Published: Jan. 1, 2023
Wastewater from textile industry contains considerable amount of dissolved dye that can trigger environmental issues if is not treated properly. Numerous methods have been developed to degrade recalcitrant pollutants safely and utterly. Among them, enzymatic treatment wastewater gaining attention due the enzyme’s specificity, easier manipulation, generation less toxic by-products. Still, cost systems main limitation keeping biocatalysts at lab-scale. Alternative solution for reducing reaction use microfluidic systems, which contribute better mixing, process intensification cleaner production. In this study, implementation horseradish peroxidase removal Acid Violet 109 performed in a reactor. The microreactor consists three plunger pump units, two mixers PTFE tube. parameters: residence time, dye, hydrogen peroxide, enzyme activity, reactors’ diameter length were optimized. Under optimal conditions: 30 mg/L concentration, 0.8 U/mL 0.1 mM 0.25 mm reactor’s diameter, 97,3 % was achieved time 6 min. results study show reactors are convenient technology removal.
Language: Английский
Citations
1
Rhizosphere, Journal Year: 2024, Volume and Issue: unknown, P. 100970 - 100970
Published: Oct. 1, 2024
Language: Английский
Citations
0
Physics of Fluids, Journal Year: 2024, Volume and Issue: 36(10)
Published: Oct. 1, 2024
The dynamics of liquid droplets surfing over the surfactant-infested free surface another have been explored experimentally. We analyze motion oil that has initiated through creation a tension gradient resulting from deposition drop surfactant at water contained in petri dish. experiments reveal location with respect to droplet position influences its motion. Due presence gradient, footprint area reduces and shape changes. studied temporal variation velocity (|vx|) relation their proximity wall. Based on evolution change velocity, can be experimentally divided into four distinct zones. Results indicate zone-1, |vx| grows t as |vx|≈tn, where n is between 0.8 1.0. scaling argument shows this zone, force dominates drag force, thereby, increases linearly expressed |vx|∝t. experimental investigation law exhibit reasonable agreement. In zone-2, remains more or less constant, it postulated balances force. zone-3, decrease results deceleration droplets. zone-4, becomes prominent approaches dish
Language: Английский
Citations
0
Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: unknown, P. 158331 - 158331
Published: Dec. 1, 2024
Language: Английский
Citations
0
Reaction Chemistry & Engineering, Journal Year: 2024, Volume and Issue: 10(3), P. 605 - 613
Published: Dec. 5, 2024
In an umbrella-shaped microchannel reactor, the continuous selective aerobic oxidation of toluene derivatives to aromatic aldehydes over a Co/Mn/Br catalytic system using acetic acid/water as solvent was studied.
Language: Английский
Citations
0