Morphology engineering of inorganic nanocrystals with deep eutectic solvents (DESs): Current developments and future prospects DOI
Bhagirath Mahto, Adnan Ali, Ashok Barhoi

et al.

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 527, P. 216406 - 216406

Published: Dec. 25, 2024

Language: Английский

One-pot synthesis of pyrimidinone and polyhydroquinoline derivatives with natural deep eutectic solvents (NADESs): Alternative to toxic organic solvents and environmental eco-friendly DOI Creative Commons

Sedigheh Ayazi Jannatabadi,

Rahman Hosseinzadeh, Behrooz Maleki

et al.

Results in Chemistry, Journal Year: 2024, Volume and Issue: 12, P. 101848 - 101848

Published: Oct. 10, 2024

Language: Английский

Citations

6
Advances in deep eutectic Solvent-Based synthesis of nanomaterials for environmental remediation DOI
Priyanka A. Shah, Vishwajit Chavda, Darshna Hirpara

et al.

Journal of Molecular Liquids, Journal Year: 2024, Volume and Issue: 416, P. 126482 - 126482

Published: Nov. 12, 2024

Language: Английский

Citations

5
Drug design, Green Synthesis, In-vitro Antibacterial and Antifungal Activities, Computational Investigation, and Molecular Docking Studies of Novel Spiro-Indoline-Pyrano-Pyrimidine and Pyrazolo Derivatives. DOI

Faiza Boukezzoula,

Oussama Khaoua,

Nora Chouha

et al.

Journal of Molecular Structure, Journal Year: 2025, Volume and Issue: unknown, P. 141684 - 141684

Published: Feb. 1, 2025

Language: Английский

Citations

0
Enzymatic Oxidation of Hydroxytyrosol in Deep Eutectic Solvents for Chitosan Functionalization and Preparation of Bioactive Nanogels DOI Open Access
Myrto G. Bellou, Anastasia Skonta, Alexandra V. Chatzikonstantinou

et al.

Catalysts, Journal Year: 2025, Volume and Issue: 15(2), P. 180 - 180

Published: Feb. 14, 2025

Biocatalytic processes for the formation of bioactive compounds and biopolymer preparations that can be applied in pharmaceuticals cosmetics are gaining increasing interest due to their safety sustainability, relying on environmentally friendly approaches biocompatible compounds. In this work, we investigate implementation various Deep Eutectic Solvents (DES) laccase-catalyzed oxidation hydroxytyrosol (HT), aiming produce its oligomer derivatives such as HT dimer trimer. The composition reaction mixture which oligomers’ yield was highest 70% v/v Bet:PG (1:4 molar ratio). oligomers formed were subsequently used non-enzymatic grafting chitosan (CS) development chitosan-based nanogels (NG). Grafted prepared by ionic gelation using sodium tripolyphosphate (TPP) a cross-linking agent. functionalized characterized Fourier-Transform Infrared (FTIR) Nuclear Magnetic Resonance (NMR) spectroscopy, while Scanning Electron Microscopy (SEM) employed nanogel characterization. Compared unmodified nanogels, grafted exhibited almost ten-fold higher antioxidant activity approximately 20% greater antibacterial activity.

Language: Английский

Citations

0
Regioselectivity for Nucleophilic Substitutions of Aryl Halides with DMF in Deep Eutectic Solvent DOI

Chen Shuang-ping,

Pan Tong, Qi Jiang

et al.

Tetrahedron, Journal Year: 2025, Volume and Issue: unknown, P. 134543 - 134543

Published: Feb. 1, 2025

Language: Английский

Citations

0
Strategies to Prepare Chitin and Chitosan-Based Bioactive Structures Aided by Deep Eutectic Solvents: A Review DOI Open Access

D. Alonzo Durante-Salmerón,

Isabel Fraile-Gutiérrez, Rubén Gil-Gonzalo

et al.

Catalysts, Journal Year: 2024, Volume and Issue: 14(6), P. 371 - 371

Published: June 10, 2024

Chitin and chitosan, abundant biopolymers derived from the shells of crustaceans cell walls fungi, have garnered considerable attention in pharmaceutical circles due to their biocompatibility, biodegradability, versatile properties. Deep eutectic solvents (DESs), emerging green composed mixtures hydrogen bond acceptors donors, offer promising avenues for enhancing solubility functionality chitin chitosan formulations. This review delves into potential utilizing DESs as highlighting efficiency dissolving these polymers, which facilitates production novel drug delivery systems, wound dressings, tissue engineering scaffolds, antimicrobial agents. The distinctive physicochemical properties DESs, including low toxicity, volatility, adaptable solvation power, enable customization chitosan-based materials meet specific requirements. Moreover, environmentally friendly nature aligns with growing demand sustainable eco-friendly processes manufacturing. revision underscores recent advances illustrating role evolving applications laying groundwork development innovative systems biomedical enhanced efficacy safety profiles.

Language: Английский

Citations

2
A Ligand-Free Approach towards Coumarin Analogs via Natural Deep Eutectic Solvent-Mediated Suzuki–Miyaura Coupling DOI Creative Commons

Annita Katopodi,

N.G. Nikolaou,

Vasiliki Kakokefalou

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(18), P. 4398 - 4398

Published: Sept. 16, 2024

A ligand-free approach for the Suzuki-Miyaura cross coupling reaction using Natural Deep Eutectic Solvents (NaDES) towards coumarin analogs is described. model between synthetically prepared 3-(4-acetyloxy-phenyl)-6-bromo-4-methyl-coumarin (3b) and phenylboronic acid was performed in five different NaDES as well pure glycerol, two inorganic bases palladium catalysts. The proceeded smoothly Choline Chloride/Glycerol (ChCl/Gly) Betaine/Glycerol (Bet/Gly) at 90 °C 24 h, affording desired product high yields up to 95%. combination of K2CO3, Pd(OAc)2 ChCl/Gly provided optimum purity compounds, while solvent successfully recycled reused times. developed methodology applicable boronic acids bearing various substituents. formation nanoparticles mixture observed, size associated with yield. In addition, all glycerol-based NaDES, an effective removal acetyl group acetyloxy–coumarin observed; thus, it noteworthy that Suzuki–Miyaura deacetylation were achieved one pot. ten novel derivatives synthesized structurally characterized 1D 2D NMR spectroscopy tested their cytotoxicity against A431 squamous cancer cell line, presenting significant activity.

Language: Английский

Citations

1
Utilizing NCP@PO(OH)2 as a Core-Shell Magnetic Nano-Catalyst for the Conversion of β-Hydroxy Nitrile to α,β-Unsaturated Carboxylic Acid DOI
Farzaneh Ebrahimzadeh

Letters in Organic Chemistry, Journal Year: 2024, Volume and Issue: 22(1), P. 70 - 77

Published: May 30, 2024

The synthesis of &#945;,&#946;-unsaturated compounds is crucial in organic chemistry, especially drug discovery and pharmaceutical development. In this study, NCP@POCl<sub>2</sub>-x (Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>@ chitosan@POCl<sub>2</sub>-x) has been introduced as a new, environmentally friendly, highly efficient heterogeneous magnetic nanocatalyst for the carboxylic acids. This catalyst facilitates <i>in situ</i> transformation POCl<sub>2</sub>-x to PO(OH)<sub>2</sub> presence water, effectively converting &#946;-hydroxy nitriles into acids through specific mechanism involving water heat. reactions display notable regioselectivity, leading high-purity products quantitative yields. NCP@PO(OH)<sub>2</sub> exhibits heterogeneity, properties, straightforward recovery, outstanding performance, making it valuable selective transformations nitriles. Additionally, can be easily separated from mixture using external forces.

Language: Английский

Citations

0
Morphology engineering of inorganic nanocrystals with deep eutectic solvents (DESs): Current developments and future prospects DOI
Bhagirath Mahto, Adnan Ali, Ashok Barhoi

et al.

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 527, P. 216406 - 216406

Published: Dec. 25, 2024

Language: Английский

Citations

0