Improvement of Asymmetric Reactions via Remote Electronic Tuning of N‐Heterocyclic Carbene Catalysts DOI
Tsubasa Inokuma, Ken‐ichi Yamada

ChemCatChem, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 1, 2024

Abstract Aminoindanol‐derived N‐heterocyclic carbene catalysts have been widely used to achieve highly enantioselective reactions. Recently, substitution at the indane moiety of has found a great impact on outcome some reactions, even though substituted position is distant from catalytic center. Especially, introduction an electron‐withdrawing group improves yield and enantioselectivity. This review provides overview recent reports improvement N‐heterocyclic‐carbene‐catalyzed asymmetric reactions by introducing remote substituents.

Language: Английский

Improvement of Asymmetric Reactions via Remote Electronic Tuning of N‐Heterocyclic Carbene Catalysts DOI
Tsubasa Inokuma, Ken‐ichi Yamada

ChemCatChem, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 1, 2024

Abstract Aminoindanol‐derived N‐heterocyclic carbene catalysts have been widely used to achieve highly enantioselective reactions. Recently, substitution at the indane moiety of has found a great impact on outcome some reactions, even though substituted position is distant from catalytic center. Especially, introduction an electron‐withdrawing group improves yield and enantioselectivity. This review provides overview recent reports improvement N‐heterocyclic‐carbene‐catalyzed asymmetric reactions by introducing remote substituents.

Language: Английский

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