Hazardous Materials from Threats to Safety: Molecularly Imprinted Polymers as Versatile Safeguarding Platforms DOI Open Access
Ana-Mihaela Gavrilă, Aurel Diacon, Tanţa-Verona Iordache

et al.

Polymers, Journal Year: 2024, Volume and Issue: 16(19), P. 2699 - 2699

Published: Sept. 24, 2024

Hazards associated with highly dangerous pollutants/contaminants in water, air, and land resources, as well food, are serious threats to public health the environment. Thus, it is imperative detect or decontaminate, risk-control strategies, possible harmful substances sensitively efficiently. In this context, due their capacity be specifically designed for various types of hazardous compounds, synthesis use molecularly imprinted polymers (MIPs) have become widespread. By molecular imprinting, affinity sites complementary shape, size, functionality can created any template molecule. MIPs' unique functions response external factors attracted researchers develop a broad range MIP-based sensors increased sensitivity, specificity, selectivity recognition element toward target compounds. Therefore, paper comprehensively reviews very recent progress MIPs smart polymer applications sensing decontamination compounds (e.g., drugs, explosives, biological chemical agents) fields from 2020 2024, providing rapid tool investigating latest research status.

Language: Английский

Functionalized Gold Nanoparticles and Halogen Bonding Interactions Involving Fentanyl and Fentanyl Derivatives DOI Creative Commons
Molly M. Sherard,

Jamie S. Kaplan,

Jeffrey H. Simpson

et al.

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(11), P. 917 - 917

Published: May 23, 2024

Fentanyl (FTN) and synthetic analogs of FTN continue to ravage populations across the globe, including in United States where opioids are increasingly being used abused causing a staggering growing number overdose deaths each year. This pandemic is worsened by ease with which can be derivatized into numerous derivatives. Understanding chemical properties/behaviors class compounds critical for developing effective detection schemes using nanoparticles (NPs) optimize important interactions. Halogen bonding (XB) an intermolecular interaction between polarized halogen atom on molecule e−-rich sites another molecule, latter present at two or more most fentanyl-type structures. Density functional theory (DFT) identify these XB acceptor different The high toxicity necessitated “fragmentation” strategy smaller, non-toxic molecules resembling parts acted as mimics intact its DFT fragments’ interactions informed solution measurements 19F NMR titrations well electrochemical self-assembled monolayer (SAM)-modified electrodes featuring donor ligands. Gold NPs, known monolayer-protected clusters (MPCs), were also functionalized strong ligands assembled films, their “fragments” studied voltammetry. Ultimately, spectroscopy TEM analysis combined study whole-molecule MPCs solution. results suggested that strongest site FTN, while common drug’s derivatives, not enough induce NP-aggregation but may better exploited sensing involving films.

Language: Английский

Citations

4
Additively manufactured ready-to-use platform using conductive recycled PLA for ketamine sensing DOI

Maria M. C. Souza,

Raquel G. Rocha,

Gilvana P. Siqueira

et al.

Microchimica Acta, Journal Year: 2025, Volume and Issue: 192(2)

Published: Jan. 9, 2025

Language: Английский

Citations

0
A novel label-free immunosensor for detection of VEGF using FFT admittance voltammetry DOI

Negar Heidari,

Reza Hassan Sajedi,

Ali Nemati Kharat

et al.

Bioelectrochemistry, Journal Year: 2025, Volume and Issue: 165, P. 108948 - 108948

Published: Feb. 21, 2025

Language: Английский

Citations

0
Electrochemical Sensors for Enhanced and Rapid Detection of Illicit Drugs DOI
Sumera Khizar,

Nadia Zine,

Monique Sigaud

et al.

Electroanalysis, Journal Year: 2025, Volume and Issue: 37(3)

Published: March 1, 2025

The consumption of illicit drugs is spread worldwide and remains a challenge for concerned authorities. Hence, it vital to develop effective precise methods detecting these types compounds in biological fluids, seized street samples, wastewaters. Electrochemical sensors are extensively used analysis many fields represent an exclusive prospect permit inexpensive, fast, accurate monitoring detection simultaneously. approaches mainly open forensic investigation because their high performance turbid complex matrices. In this minireview, recent electrochemical strategies applied the different samples have been presented.

Language: Английский

Citations

0
Fouling-Resistant Voltammetric Xylazine Sensors for Detection of the Street Drug “Tranq” DOI Creative Commons

Jerry O. Stern,

Ann H. Wemple,

C. W. Sheppard

et al.

Toxics, Journal Year: 2024, Volume and Issue: 12(11), P. 791 - 791

Published: Oct. 30, 2024

As the opioid crisis continues to wreak havoc on a global scale, it is increasingly critical develop methodologies detect most dangerous drugs such as fentanyl and its derivatives, which have orders of magnitude higher potency than morphine. The scientific challenge for chemical detection derivatives complicated by both constantly increasing synthetic variations drug well expanded use adulterants. One tragically consequential example nocuous street known "Tranq", combines or derivative with veterinary sedative Rompun

Language: Английский

Citations

2
Hazardous Materials from Threats to Safety: Molecularly Imprinted Polymers as Versatile Safeguarding Platforms DOI Open Access
Ana-Mihaela Gavrilă, Aurel Diacon, Tanţa-Verona Iordache

et al.

Polymers, Journal Year: 2024, Volume and Issue: 16(19), P. 2699 - 2699

Published: Sept. 24, 2024

Hazards associated with highly dangerous pollutants/contaminants in water, air, and land resources, as well food, are serious threats to public health the environment. Thus, it is imperative detect or decontaminate, risk-control strategies, possible harmful substances sensitively efficiently. In this context, due their capacity be specifically designed for various types of hazardous compounds, synthesis use molecularly imprinted polymers (MIPs) have become widespread. By molecular imprinting, affinity sites complementary shape, size, functionality can created any template molecule. MIPs' unique functions response external factors attracted researchers develop a broad range MIP-based sensors increased sensitivity, specificity, selectivity recognition element toward target compounds. Therefore, paper comprehensively reviews very recent progress MIPs smart polymer applications sensing decontamination compounds (e.g., drugs, explosives, biological chemical agents) fields from 2020 2024, providing rapid tool investigating latest research status.

Language: Английский

Citations

2