Effect of radioactive iodine therapy on hematological parameters in patients with thyroid cancer: systematic review and meta-analysis DOI Creative Commons
Dereje Mengesha Berta, Bisrat Birke Teketelew, Negesse Cherie

et al.

Frontiers in Endocrinology, Journal Year: 2025, Volume and Issue: 16

Published: March 14, 2025

Patients with thyroid cancer (TC) are commonly treated radioactive iodine therapy (RIA) to prevent neoplastic transformation and the re-emergence of cells. However, it has major side effects on blood degree change in hematological parameters reported varies across studies. Therefore, aim this review was assesses mean differences after RAI therapy. The relevant articles for were identified through extensive searches databases Google search engine. subsequently selected using predetermined eligibility criteria. All information from screened extracted. pooled standardized (SMDs) assessed via a random model. heterogeneity determined by I2 statistics test. Funnel plots Egger's test utilized assess publication bias. A total 17 studies including 4,112 3,766 study participants before therapy, respectively, included. SMDs leucocyte count (TLC) (*109/L) at one, three, six 12 months last follow-up period 2.39, 2.46, 5.84, 3.19, 0.53, respectively. Changes TLC three statistically significant. In terms absolute neutrophil (ANC; *109/L) lymphocyte (ALC; *109/L), 6.32 7.37, addition, significant changes platelet (PLT; observed follow-up, 7.01, 0.22, 2.63, 6.61, 8.76, Furthermore, red cells (RBCs; *1012/L) hemoglobin (Hgb; g/dl) detected -1.088 2.4, According current systematic meta-analysis, radioiodine had effect parameters. Thus, early screening correction toxicity may be helpful improving quality life patients receiving https://www.crd.york.ac.uk/prospero/, identifier CRD42024586449.

Language: Английский

Diagnostic accuracy of ultrasound in hyperthyroidism: A comprehensive review of recent studies DOI

Dawei Wang,

Chao Xie,

Xuena Zheng

et al.

Journal of Radiation Research and Applied Sciences, Journal Year: 2025, Volume and Issue: 18(2), P. 101370 - 101370

Published: Feb. 26, 2025

Language: Английский

Citations

0
Effect of radioactive iodine therapy on hematological parameters in patients with thyroid cancer: systematic review and meta-analysis DOI Creative Commons
Dereje Mengesha Berta, Bisrat Birke Teketelew, Negesse Cherie

et al.

Frontiers in Endocrinology, Journal Year: 2025, Volume and Issue: 16

Published: March 14, 2025

Patients with thyroid cancer (TC) are commonly treated radioactive iodine therapy (RIA) to prevent neoplastic transformation and the re-emergence of cells. However, it has major side effects on blood degree change in hematological parameters reported varies across studies. Therefore, aim this review was assesses mean differences after RAI therapy. The relevant articles for were identified through extensive searches databases Google search engine. subsequently selected using predetermined eligibility criteria. All information from screened extracted. pooled standardized (SMDs) assessed via a random model. heterogeneity determined by I2 statistics test. Funnel plots Egger's test utilized assess publication bias. A total 17 studies including 4,112 3,766 study participants before therapy, respectively, included. SMDs leucocyte count (TLC) (*109/L) at one, three, six 12 months last follow-up period 2.39, 2.46, 5.84, 3.19, 0.53, respectively. Changes TLC three statistically significant. In terms absolute neutrophil (ANC; *109/L) lymphocyte (ALC; *109/L), 6.32 7.37, addition, significant changes platelet (PLT; observed follow-up, 7.01, 0.22, 2.63, 6.61, 8.76, Furthermore, red cells (RBCs; *1012/L) hemoglobin (Hgb; g/dl) detected -1.088 2.4, According current systematic meta-analysis, radioiodine had effect parameters. Thus, early screening correction toxicity may be helpful improving quality life patients receiving https://www.crd.york.ac.uk/prospero/, identifier CRD42024586449.

Language: Английский

Citations

0